STRINGSTRING
LOC100709663 LOC100709663 LOC100705232 LOC100705232 I3KB41_ORENI I3KB41_ORENI LOC100704899 LOC100704899 cops3 cops3 ets1 ets1 irf7 irf7 Ubr2 Ubr2 depdc5 depdc5 etv1 etv1 rgs7 rgs7 larp1 larp1 I3KF85_ORENI I3KF85_ORENI fli1 fli1 irf9 irf9 CUL7 CUL7 foxp3 foxp3 psmd3 psmd3 rgs11 rgs11 LOC100706939 LOC100706939 LOC100699655 LOC100699655 LOC100698576 LOC100698576 larp7 larp7 ell2 ell2 LOC109194151 LOC109194151 cul1 cul1 e2f4 e2f4 I3JS89_ORENI I3JS89_ORENI I3J1E8_ORENI I3J1E8_ORENI spi1 spi1 Foxi3 Foxi3 mnd1 mnd1 adar adar LOC100703753 LOC100703753 deptor deptor cops4 cops4 ssb ssb LOC100701059 LOC100701059 I3L036_ORENI I3L036_ORENI foxd3 foxd3 LOC100704249 LOC100704249 foxb2 foxb2 LOC100708053 LOC100708053 LOC100707784 LOC100707784 foxe1 foxe1 I3KXG9_ORENI I3KXG9_ORENI I3KWT2_ORENI I3KWT2_ORENI foxp1 foxp1 UBR1 UBR1 LOC100702954 LOC100702954 RPS19 RPS19 plek2 plek2 LOC100708764 LOC100708764 I3KT41_ORENI I3KT41_ORENI I3KSH5_ORENI I3KSH5_ORENI irf6 irf6 LOC100705944 LOC100705944 I3KQY8_ORENI I3KQY8_ORENI etv4 etv4 LOC100706559 LOC100706559 snf8 snf8 I3KNS1_ORENI I3KNS1_ORENI METAP2 METAP2 LARP4B LARP4B LOC100706474 LOC100706474 I3KKZ9_ORENI I3KKZ9_ORENI LOC100699532 LOC100699532 dvl1 dvl1 LOC100698455 LOC100698455 foxp2 foxp2 LOC100711715 LOC100711715 Ascc3 Ascc3 rpa2 rpa2 KAT6B KAT6B LOC100689943 LOC100689943 foxi2 foxi2 HSF1 HSF1 blm blm SPDEF SPDEF rfx4 rfx4 ehf ehf LOC100709151 LOC100709151 gabpa gabpa Prex2 Prex2 tfdp1 tfdp1 rfx3 rfx3 pikfyve pikfyve LOC100698623 LOC100698623 riok2 riok2 LOC100705420 LOC100705420 foxn4 foxn4 cops2 cops2 foxo3 foxo3 LOC100690925 LOC100690925 LOC100711208 LOC100711208 e2f7 e2f7 arid2 arid2 LOC100702561 LOC100702561 larp4 larp4 LOC100690330 LOC100690330 LOC100711448 LOC100711448 snrnp200 snrnp200 LOC100700965 LOC100700965 LOC100689894 LOC100689894 LOC100696396 LOC100696396 I3JVD4_ORENI I3JVD4_ORENI rfx2 rfx2 CUL3 CUL3 ETV6 ETV6 FOXN2 FOXN2 irf4 irf4 LOC100700789 LOC100700789 LOC100704864 LOC100704864 Anapc2 Anapc2 stn1 stn1 I3JQL3_ORENI I3JQL3_ORENI gtf2e2 gtf2e2 rapgef4 rapgef4 ELK3 ELK3 LOC100694937 LOC100694937 LOC100692791 LOC100692791 LOC100709336 LOC100709336 rgs9 rgs9 I3JLK9_ORENI I3JLK9_ORENI irf5 irf5 LOC100710134 LOC100710134 E2f8 E2f8 E2F3 E2F3 LOC100709014 LOC100709014 Polr3f Polr3f psmd12 psmd12 foxf2 foxf2 I3JGT5_ORENI I3JGT5_ORENI LOC100697996 LOC100697996 RFX7 RFX7 LOC100705578 LOC100705578 foxf1 foxf1 irf8 irf8 eif3m eif3m foxo4 foxo4 LOC100691340 LOC100691340 LOC100701117 LOC100701117 Ell Ell vps36 vps36 asmt asmt FOXJ3 FOXJ3 depdc1 depdc1 DDRGK1 DDRGK1 cul2 cul2 elf2 elf2 elk4 elk4 gtf2f2 gtf2f2 Foxk1 Foxk1 LOC100709513 LOC100709513 LOC100712278 LOC100712278 LOC100693896 LOC100693896 I3J1F9_ORENI I3J1F9_ORENI LOC100709782 LOC100709782 dvl2 dvl2 rfx6 rfx6 LOC100691937 LOC100691937 cul4a cul4a CUL5 CUL5 pa2g4 pa2g4 psmd6 psmd6 plek plek psmd13 psmd13 gtf2f1 gtf2f1 I3J0X1_ORENI I3J0X1_ORENI hsf2 hsf2 eif3k eif3k LOC100706200 LOC100706200 foxn3 foxn3 I3IW99_ORENI I3IW99_ORENI shprh shprh gtf3c1 gtf3c1 cdc6 cdc6 LOC100694149 LOC100694149 helq helq LOC100703712 LOC100703712 I3JM20_ORENI I3JM20_ORENI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100709663Interferon regulatory factor 10. (403 aa)
LOC100705232Uncharacterized protein. (516 aa)
I3KB41_ORENIREC8 meiotic recombination protein b. (361 aa)
LOC100704899Interferon regulatory factor. (319 aa)
cops3COP9 signalosome subunit 3. (423 aa)
ets1V-ets avian erythroblastosis virus E26 oncogene homolog 1. (546 aa)
irf7Interferon regulatory factor 7. (461 aa)
Ubr2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1693 aa)
depdc5DEP domain containing 5. (1578 aa)
etv1Ets variant 1. (494 aa)
rgs7Regulator of G protein signaling 7a. (496 aa)
larp1La ribonucleoprotein domain family, member 1. (1107 aa)
I3KF85_ORENIUncharacterized protein. (443 aa)
fli1Fli-1 proto-oncogene, ETS transcription factor a. (457 aa)
irf9Interferon regulatory factor 9. (461 aa)
CUL7Cullin 7; Belongs to the cullin family. (2649 aa)
foxp3Fork-head domain-containing protein. (390 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (575 aa)
rgs11Regulator of G protein signaling 11. (470 aa)
LOC100706939Forkhead box O1 a. (671 aa)
LOC100699655General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (322 aa)
LOC100698576Zgc:152951. (501 aa)
larp7La ribonucleoprotein domain family, member 7. (568 aa)
ell2Elongation factor, RNA polymerase II, 2. (668 aa)
LOC109194151CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
cul1Cullin 1b; Belongs to the cullin family. (1038 aa)
e2f4E2F transcription factor 4. (407 aa)
I3JS89_ORENIPhosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1604 aa)
I3J1E8_ORENIRegulatory factor X, 1a (influences HLA class II expression). (879 aa)
spi1Spi-1 proto-oncogene b. (276 aa)
Foxi3Forkhead box I2. (366 aa)
mnd1Meiotic nuclear division protein 1 homolog; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (205 aa)
adarAdenosine deaminase RNA specific. (1363 aa)
LOC100703753CULLIN_2 domain-containing protein; Belongs to the cullin family. (836 aa)
deptorDEP domain containing MTOR-interacting protein. (421 aa)
cops4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis). (421 aa)
ssbSmall RNA binding exonuclease protection factor La. (380 aa)
LOC100701059Forkhead box Q1a. (273 aa)
I3L036_ORENIForkhead box C1. (432 aa)
foxd3Forkhead box D3. (397 aa)
LOC100704249Forkhead box D5. (348 aa)
foxb2Forkhead box B2. (318 aa)
LOC100708053Forkhead box E3. (416 aa)
LOC100707784Fork-head domain-containing protein. (361 aa)
foxe1Forkhead box E1. (368 aa)
I3KXG9_ORENIForkhead box D1. (319 aa)
I3KWT2_ORENISi:dkeyp-97e7.9. (404 aa)
foxp1Forkhead box P1. (679 aa)
UBR1E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1740 aa)
LOC100702954Interferon regulatory factor 3. (466 aa)
RPS19Ribosomal protein S19. (175 aa)
plek2Pleckstrin 2. (359 aa)
LOC100708764Uncharacterized protein. (616 aa)
I3KT41_ORENIForkhead box P4. (674 aa)
I3KSH5_ORENILa ribonucleoprotein domain family, member 4Ab. (329 aa)
irf6Interferon regulatory factor 6. (490 aa)
LOC100705944Fork-head domain-containing protein. (381 aa)
I3KQY8_ORENISi:ch211-195d17.2. (401 aa)
etv4Ets variant 4. (535 aa)
LOC100706559Proteasome 26S subunit, non-ATPase 11b. (424 aa)
snf8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (257 aa)
I3KNS1_ORENIFork-head domain-containing protein. (302 aa)
METAP2Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (468 aa)
LARP4BLa ribonucleoprotein domain family member 4B. (770 aa)
LOC100706474Forkhead box I3b. (392 aa)
I3KKZ9_ORENIUncharacterized protein. (614 aa)
LOC100699532Fork-head domain-containing protein. (591 aa)
dvl1Dishevelled segment polarity protein 1a. (722 aa)
LOC100698455RAD21 cohesin complex component like 1. (547 aa)
foxp2Forkhead box P2. (763 aa)
LOC100711715Rap guanine nucleotide exchange factor (GEF) 3. (867 aa)
Ascc3Activating signal cointegrator 1 complex subunit 3. (2200 aa)
rpa2Replication protein A2. (278 aa)
KAT6BHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (872 aa)
LOC100689943Ribosomal protein S19. (163 aa)
foxi2Forkhead box i1. (376 aa)
HSF1Heat shock transcription factor 1. (546 aa)
blmBLM RecQ like helicase. (1407 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (334 aa)
rfx4Regulatory factor X, 4. (737 aa)
ehfEts homologous factor. (276 aa)
LOC100709151Forkhead box H1. (514 aa)
gabpaGA binding protein transcription factor subunit alpha. (447 aa)
Prex2Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2. (1599 aa)
tfdp1Transcription factor. (413 aa)
rfx3Regulatory factor X, 3 (influences HLA class II expression). (766 aa)
pikfyvePhosphoinositide kinase, FYVE finger containing. (2087 aa)
LOC100698623Ets variant 5a. (539 aa)
riok2RIO kinase 2 (yeast). (524 aa)
LOC100705420RAD21 cohesin complex component b. (649 aa)
foxn4Forkhead box N4. (515 aa)
cops2COP9 signalosome subunit 2. (438 aa)
foxo3Forkhead box O3b. (664 aa)
LOC100690925La ribonucleoprotein domain family, member 1B. (1088 aa)
LOC100711208Proliferation-associated 2G4, b. (392 aa)
e2f7E2F transcription factor 7. (752 aa)
arid2AT rich interactive domain 2 (ARID, RFX-like). (1688 aa)
LOC100702561Spi-C transcription factor (Spi-1/PU.1 related). (274 aa)
larp4La ribonucleoprotein domain family, member 4Aa. (806 aa)
LOC100690330ETS transcription factor ELK3. (385 aa)
LOC100711448DEP domain containing 7. (580 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2136 aa)
LOC100700965Dishevelled segment polarity protein 3a. (686 aa)
LOC100689894Zgc:171558. (996 aa)
LOC100696396Forkhead box O6 b. (731 aa)
I3JVD4_ORENIHeat shock transcription factor 4. (404 aa)
rfx2Regulatory factor X, 2 (influences HLA class II expression). (736 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
ETV6ETS variant 6. (492 aa)
FOXN2Forkhead box N2b. (409 aa)
irf4Interferon regulatory factor 4a. (460 aa)
LOC100700789Forkhead box F2a. (381 aa)
LOC100704864Forkhead box K2. (609 aa)
Anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (797 aa)
stn1CST complex subunit STN1; Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication. (365 aa)
I3JQL3_ORENIFork-head domain-containing protein. (533 aa)
gtf2e2Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (286 aa)
rapgef4Rap guanine nucleotide exchange factor (GEF) 4. (1015 aa)
ELK3ETS transcription factor ELK3. (499 aa)
LOC100694937Regulatory factor X7b. (1488 aa)
LOC100692791ETS domain-containing protein. (256 aa)
LOC100709336Forkhead box A2. (413 aa)
rgs9Regulator of G protein signaling 9b. (659 aa)
I3JLK9_ORENIE2F_TDP domain-containing protein. (249 aa)
irf5Interferon regulatory factor 5. (474 aa)
LOC100710134RAD21 cohesin complex component a. (637 aa)
E2f8E2F transcription factor 8. (401 aa)
E2F3E2F transcription factor 3. (444 aa)
LOC100709014Forkhead box R1. (304 aa)
Polr3fDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
foxf2Forkhead box F2b. (382 aa)
I3JGT5_ORENIForkhead box Q1b. (247 aa)
LOC100697996Interferon regulatory factor 4b. (450 aa)
RFX7Regulatory factor X7. (1409 aa)
LOC100705578E2F_TDP domain-containing protein. (79 aa)
foxf1Forkhead box F1. (379 aa)
irf8Interferon regulatory factor 8. (420 aa)
eif3mEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (375 aa)
foxo4Forkhead box O4. (644 aa)
LOC100691340Fork-head domain-containing protein. (398 aa)
LOC100701117Forkhead box Q2. (294 aa)
EllElongation factor RNA polymerase II. (677 aa)
vps36Vacuolar protein sorting 36 homolog. (382 aa)
asmtAcetylserotonin O-methyltransferase. (358 aa)
FOXJ3Forkhead box J3. (636 aa)
depdc1DEP domain containing 1a. (869 aa)
DDRGK1DDRGK domain containing 1. (299 aa)
cul2Cullin 2; Belongs to the cullin family. (769 aa)
elf2E74-like factor 2b (ets domain transcription factor). (687 aa)
elk4ETS transcription factor ELK4. (483 aa)
gtf2f2General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (297 aa)
Foxk1Forkhead box K1. (711 aa)
LOC100709513E74-like factor 3 (ets domain transcription factor, epithelial-specific ). (388 aa)
LOC100712278E74-like ETS transcription factor 1. (666 aa)
LOC100693896Ets variant 2. (371 aa)
I3J1F9_ORENIFork-head domain-containing protein. (637 aa)
LOC100709782Regulator of G protein signaling 6. (538 aa)
dvl2Dishevelled segment polarity protein 2. (767 aa)
rfx6Regulatory factor X, 6. (959 aa)
LOC100691937Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (461 aa)
cul4aCullin 4A; Belongs to the cullin family. (819 aa)
CUL5Cullin 5; Belongs to the cullin family. (797 aa)
pa2g4Proliferation-associated 2G4, a. (391 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (407 aa)
plekPleckstrin. (391 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (379 aa)
gtf2f1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (547 aa)
I3J0X1_ORENIRap guanine nucleotide exchange factor (GEF) 5a. (869 aa)
hsf2Heat shock transcription factor 2. (529 aa)
eif3kEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (212 aa)
LOC100706200Uncharacterized protein. (618 aa)
foxn3Checkpoint suppressor 1. (486 aa)
I3IW99_ORENIHeterochromatin protein 1, binding protein 3. (514 aa)
shprhSNF2 histone linker PHD RING helicase. (1661 aa)
gtf3c1General transcription factor IIIC subunit 1. (2226 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (604 aa)
LOC100694149Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (462 aa)
helqHelicase, POLQ like. (999 aa)
LOC100703712PCI domain-containing protein. (445 aa)
I3JM20_ORENIRegulator of G protein signaling 9a. (455 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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