STRINGSTRING
chd8 chd8 LOC100699288 LOC100699288 I3KNN9_ORENI I3KNN9_ORENI smarca4 smarca4 Chd7 Chd7 I3IV57_ORENI I3IV57_ORENI chd9 chd9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2621 aa)
LOC100699288SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1626 aa)
I3KNN9_ORENIUncharacterized protein. (1608 aa)
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a. (1628 aa)
Chd7Chromodomain helicase DNA binding protein 7. (2854 aa)
I3IV57_ORENIChromodomain helicase DNA binding protein 6. (2730 aa)
chd9Chromodomain helicase DNA binding protein 9. (3005 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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