STRINGSTRING
pole2 pole2 rpa3 rpa3 cul4a cul4a pold2 pold2 oxtr oxtr ENSONIP00000047919 ENSONIP00000047919 LOC100697269 LOC100697269 pole3 pole3 ENSONIP00000002713 ENSONIP00000002713 LOC100708142 LOC100708142 pole4 pole4 dtl dtl rbx1 rbx1 usp1 usp1 rfc1 rfc1 rfc5 rfc5 LOC100701531 LOC100701531 rfc3 rfc3 uba52 uba52 pole pole rfc2 rfc2 kxd1 kxd1 pold3 pold3 wdr48 wdr48 rps27a rps27a rpa2 rpa2 LOC102079736 LOC102079736 rfc4 rfc4 Pold1 Pold1 meiob meiob RPA1 RPA1 Cul4b Cul4b pold4 pold4 RCBTB1 RCBTB1 ddb1 ddb1 pcna pcna rpa1 rpa1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (539 aa)
rpa3Replication protein A3. (122 aa)
cul4aCullin 4A; Belongs to the cullin family. (819 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (500 aa)
oxtrRAD18 E3 ubiquitin protein ligase. (497 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
LOC100697269Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2. (559 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
ENSONIP00000002713annotation not available (760 aa)
LOC100708142SCY domain-containing protein. (126 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (128 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (661 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
usp1Ubiquitin carboxyl-terminal hydrolase. (830 aa)
rfc1Replication factor C subunit 1. (1169 aa)
rfc5Replication factor C (activator 1) 5. (341 aa)
LOC100701531Regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1. (591 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
rfc2Replication factor C (activator 1) 2. (361 aa)
kxd1KxDL motif containing 1. (184 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (447 aa)
wdr48WD repeat domain 48b. (690 aa)
rps27aRibosomal protein S27a. (156 aa)
rpa2Replication protein A2. (278 aa)
LOC102079736Uncharacterized protein. (966 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
Pold1DNA polymerase. (1105 aa)
meiobMethionine sulfoxide reductase B1b. (464 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (665 aa)
Cul4bCullin-4B. (869 aa)
pold4DNA polymerase delta subunit 4. (107 aa)
RCBTB1RCC1 and BTB domain containing protein 1. (571 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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