16 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fdx2	Ferredoxin 2. (196 aa)
	SLC25A28	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (400 aa)
	nfs1	NFS1 cysteine desulfurase. (447 aa)
	glrx5	Glutaredoxin 5 homolog (S. cerevisiae). (156 aa)
	hscb	Si:ch211-207k7.4. (280 aa)
	I3K114_ORENI	Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family. (338 aa)
	FDX1	Ferredoxin 1. (147 aa)
	Iscu	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
	LOC100705178	Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa)
	Fxn	Frataxin, mitochondrial. (122 aa)
	Lyrm4	LYR motif-containing protein 4. (153 aa)
	slc25a28	Solute carrier family 25 member 28; Belongs to the mitochondrial carrier (TC 2.A.29) family. (401 aa)
	FADS6	Fatty acid desaturase 6. (372 aa)
	isca2	Iron-sulfur cluster assembly 2. (176 aa)
	isca1	Iron-sulfur cluster assembly 1 homolog, mitochondrial. (129 aa)
	fdxr	NADPH:adrenodoxin oxidoreductase, mitochondrial. (503 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FADS6	FDX1	ENSONIP00000050217	ENSONIP00000015113	Fatty acid desaturase 6.	Ferredoxin 1.	0.935
FADS6	Fxn	ENSONIP00000050217	ENSONIP00000029150	Fatty acid desaturase 6.	Frataxin, mitochondrial.	0.567
FADS6	Lyrm4	ENSONIP00000050217	ENSONIP00000031573	Fatty acid desaturase 6.	LYR motif-containing protein 4.	0.568
FADS6	fdx2	ENSONIP00000050217	ENSONIP00000022765	Fatty acid desaturase 6.	Ferredoxin 2.	0.935
FADS6	isca1	ENSONIP00000050217	ENSONIP00000065877	Fatty acid desaturase 6.	Iron-sulfur cluster assembly 1 homolog, mitochondrial.	0.566
FADS6	isca2	ENSONIP00000050217	ENSONIP00000063522	Fatty acid desaturase 6.	Iron-sulfur cluster assembly 2.	0.480
FADS6	nfs1	ENSONIP00000050217	ENSONIP00000000668	Fatty acid desaturase 6.	NFS1 cysteine desulfurase.	0.589
FDX1	FADS6	ENSONIP00000015113	ENSONIP00000050217	Ferredoxin 1.	Fatty acid desaturase 6.	0.935
FDX1	Fxn	ENSONIP00000015113	ENSONIP00000029150	Ferredoxin 1.	Frataxin, mitochondrial.	0.830
FDX1	Iscu	ENSONIP00000015113	ENSONIP00000016866	Ferredoxin 1.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.886
FDX1	LOC100705178	ENSONIP00000015113	ENSONIP00000017501	Ferredoxin 1.	Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.886
FDX1	Lyrm4	ENSONIP00000015113	ENSONIP00000031573	Ferredoxin 1.	LYR motif-containing protein 4.	0.841
FDX1	fdxr	ENSONIP00000015113	ENSONIP00000077240	Ferredoxin 1.	NADPH:adrenodoxin oxidoreductase, mitochondrial.	0.953
FDX1	isca1	ENSONIP00000015113	ENSONIP00000065877	Ferredoxin 1.	Iron-sulfur cluster assembly 1 homolog, mitochondrial.	0.716
FDX1	isca2	ENSONIP00000015113	ENSONIP00000063522	Ferredoxin 1.	Iron-sulfur cluster assembly 2.	0.673
FDX1	nfs1	ENSONIP00000015113	ENSONIP00000000668	Ferredoxin 1.	NFS1 cysteine desulfurase.	0.930
Fxn	FADS6	ENSONIP00000029150	ENSONIP00000050217	Frataxin, mitochondrial.	Fatty acid desaturase 6.	0.567
Fxn	FDX1	ENSONIP00000029150	ENSONIP00000015113	Frataxin, mitochondrial.	Ferredoxin 1.	0.830
Fxn	I3K114_ORENI	ENSONIP00000029150	ENSONIP00000014809	Frataxin, mitochondrial.	Solute carrier family 25 member 37; Belongs to the mitochondrial carrier (TC 2.A.29) family.	0.653
Fxn	Iscu	ENSONIP00000029150	ENSONIP00000016866	Frataxin, mitochondrial.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.970