STRINGSTRING
LOC100707972 LOC100707972 mtx2 mtx2 atp5pd atp5pd atp5f1d atp5f1d atp5pb atp5pb LOC100695831 LOC100695831 LOC100692587 LOC100692587 gabpb2 gabpb2 sirt5 sirt5 I3JIX5_ORENI I3JIX5_ORENI glud1 glud1 Srfbp1 Srfbp1 twnk twnk tfb1m tfb1m atp5mf atp5mf atp5mc3 atp5mc3 pprc1 pprc1 LOC100701603 LOC100701603 nrf1 nrf1 atp5po atp5po Sod2 Sod2 gabpa gabpa sirt4 sirt4 dnajc11 dnajc11 immt immt micos10 micos10 ATP6 ATP6 LOC100694756 LOC100694756 I3KTI7_ORENI I3KTI7_ORENI I3KYU4_ORENI I3KYU4_ORENI ppargc1a ppargc1a ENSONIP00000030681 ENSONIP00000030681 I3K0I7_ORENI I3K0I7_ORENI LOC100692411 LOC100692411 atp5f1e atp5f1e tmem11 tmem11 ENSONIP00000044449 ENSONIP00000044449 atp5f1a atp5f1a dmac2l dmac2l ENSONIP00000047002 ENSONIP00000047002 LOC100707874 LOC100707874 micos13 micos13 LOC100709974 LOC100709974 LOC100693141 LOC100693141 I3J6Z6_ORENI I3J6Z6_ORENI atp5f1c atp5f1c ppargc1b ppargc1b polg2 polg2 LOC100695844 LOC100695844 CRTC2 CRTC2 LOC100706680 LOC100706680 LOC100709019 LOC100709019 LOC100702682 LOC100702682 sirt3 sirt3 atp5pf atp5pf LOC100696915 LOC100696915 ENSONIP00000074870 ENSONIP00000074870 ssbp1 ssbp1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100707972Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (542 aa)
mtx2Metaxin 2. (259 aa)
atp5pdATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (161 aa)
atp5f1dATP synthase F1 subunit delta. (192 aa)
atp5pbATP synthase peripheral stalk-membrane subunit b. (292 aa)
LOC100695831ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (141 aa)
LOC100692587ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (137 aa)
gabpb2GA binding protein transcription factor subunit beta 2a. (431 aa)
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (301 aa)
I3JIX5_ORENICREB regulated transcription coactivator 3. (783 aa)
glud1Glutamate dehydrogenase 1a; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (548 aa)
Srfbp1Uncharacterized protein. (522 aa)
twnkTwinkle mtDNA helicase. (720 aa)
tfb1mrRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (358 aa)
atp5mfATP synthase membrane subunit f. (113 aa)
atp5mc3ATP synthase membrane subunit c locus 2; Belongs to the ATPase C chain family. (139 aa)
pprc1PPARG related coactivator 1. (1336 aa)
LOC100701603NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)
nrf1Nuclear respiratory factor 1. (503 aa)
atp5poATP synthase peripheral stalk subunit OSCP. (209 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (294 aa)
gabpaGA binding protein transcription factor subunit alpha. (447 aa)
sirt4NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily. (310 aa)
dnajc11DnaJ (Hsp40) homolog, subfamily C, member 11a. (559 aa)
immtMICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (759 aa)
micos10MICOS complex subunit MIC10; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (93 aa)
ATP6ATP synthase subunit a. (227 aa)
LOC100694756DnaJ (Hsp40) homolog, subfamily C, member 11b. (560 aa)
I3KTI7_ORENIMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (200 aa)
I3KYU4_ORENIMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (192 aa)
ppargc1aPPARG coactivator 1 alpha. (1284 aa)
ENSONIP00000030681annotation not available (75 aa)
I3K0I7_ORENIMICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (482 aa)
LOC100692411NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (443 aa)
atp5f1eATP synthase F1 subunit epsilon. (72 aa)
tmem11Transmembrane protein 11. (181 aa)
ENSONIP00000044449F-type H+-transporting ATPase subunit g. (160 aa)
atp5f1aATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (578 aa)
dmac2lDistal membrane arm assembly complex 2 like. (225 aa)
ENSONIP00000047002annotation not available (79 aa)
LOC100707874Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (456 aa)
micos13MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (113 aa)
LOC100709974ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (570 aa)
LOC100693141ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (550 aa)
I3J6Z6_ORENIATP synthase membrane subunit ea. (107 aa)
atp5f1cATP synthase subunit gamma. (294 aa)
ppargc1bUncharacterized protein. (927 aa)
polg2DNA polymerase subunit gamma-2, mitochondrial isoform X1. (452 aa)
LOC100695844Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial. (261 aa)
CRTC2CREB regulated transcription coactivator 2. (61 aa)
LOC100706680Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1. (1167 aa)
LOC100709019ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (103 aa)
LOC100702682Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (593 aa)
sirt3NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (403 aa)
atp5pfATP synthase-coupling factor 6, mitochondrial. (140 aa)
LOC100696915Uncharacterized protein. (521 aa)
ENSONIP00000074870annotation not available (107 aa)
ssbp1Single-stranded DNA binding protein 1. (147 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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