STRINGSTRING
mkx mkx LOC100705918 LOC100705918 I3JI97_ORENI I3JI97_ORENI irx2 irx2 I3JG35_ORENI I3JG35_ORENI itgb3 itgb3 LOC100691078 LOC100691078 smurf1 smurf1 sp1 sp1 I3JD82_ORENI I3JD82_ORENI LOC100705094 LOC100705094 meis2 meis2 LOC100699105 LOC100699105 ENSONIP00000067993 ENSONIP00000067993 Itgb5 Itgb5 LOC102075629 LOC102075629 I3IXF2_ORENI I3IXF2_ORENI LOC100705189 LOC100705189 SMURF2 SMURF2 LOC100691730 LOC100691730 I3KPC3_ORENI I3KPC3_ORENI SMAD3 SMAD3 nedd4l nedd4l LOC100700558 LOC100700558 meis1 meis1 parp1 parp1 LOC100697722 LOC100697722 usp9x usp9x LOC100690952 LOC100690952 mapk1 mapk1 ENSONIP00000077937 ENSONIP00000077937 LOC100693777 LOC100693777 I3KQQ1_ORENI I3KQQ1_ORENI LOC100705673 LOC100705673 smad7 smad7 LOC100707272 LOC100707272 cgn cgn LOC100694653 LOC100694653 rnf111 rnf111 LOC100705578 LOC100705578 LOC100690458 LOC100690458 LTBP3 LTBP3 rbl1 rbl1 LOC100703449 LOC100703449 LOC100700916 LOC100700916 bambi bambi PARD3 PARD3 itgb6 itgb6 Irx3 Irx3 irx5 irx5 atp1b4 atp1b4 ENSONIP00000001443 ENSONIP00000001443 snw1 snw1 ccnk ccnk LOC100692950 LOC100692950 trim33 trim33 STUB1 STUB1 LOC100692645 LOC100692645 Itgb8 Itgb8 ncor2 ncor2 ltbp1 ltbp1 cdk19 cdk19 LOC100699525 LOC100699525 I3K1Z3_ORENI I3K1Z3_ORENI LOC100709139 LOC100709139 I3K2K5_ORENI I3K2K5_ORENI cdk9 cdk9 uba52 uba52 strap strap ncor1 ncor1 LOC100712573 LOC100712573 cdk8 cdk8 I3JLM4_ORENI I3JLM4_ORENI tfdp1 tfdp1 kxd1 kxd1 LOC100698856 LOC100698856 LOC100710008 LOC100710008 smad3 smad3 LOC100710325 LOC100710325 rps27a rps27a LOC106098551 LOC106098551 LOC100711982 LOC100711982 LOC100710680 LOC100710680 LOC100703104 LOC100703104 Zfyve9 Zfyve9 LOC100696648 LOC100696648 TGFBR2 TGFBR2 tgfb3 tgfb3 LOC100707881 LOC100707881 ldlrad4 ldlrad4 FBN1 FBN1 men1 men1 irx6 irx6 tgfb2 tgfb2 LOC100703326 LOC100703326 arhgef18 arhgef18 LOC100690293 LOC100690293 LOC100695177 LOC100695177 LOC100699888 LOC100699888 ccnq ccnq e2f4 e2f4 ski ski I3KZC4_ORENI I3KZC4_ORENI LOC100711516 LOC100711516 LOC100707005 LOC100707005 LOC100698210 LOC100698210 ENSONIP00000047919 ENSONIP00000047919 LOC100708381 LOC100708381 LOC100690070 LOC100690070 ccnc ccnc LOC100705046 LOC100705046 furin furin LOC100710602 LOC100710602
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mkxMohawk homeobox a. (375 aa)
LOC100705918TGFB-induced factor homeobox 1. (330 aa)
I3JI97_ORENIHomeobox domain-containing protein. (416 aa)
irx2Iroquois homeobox 2a. (511 aa)
I3JG35_ORENICbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (844 aa)
LOC100691078E3 ubiquitin-protein ligase. (844 aa)
smurf1E3 ubiquitin-protein ligase. (745 aa)
sp1Sp1 transcription factor. (726 aa)
I3JD82_ORENIF11 receptor, tandem duplicate 1. (320 aa)
LOC100705094Mothers against decapentaplegic homolog. (765 aa)
meis2Meis homeobox 2a. (480 aa)
LOC100699105Integrin beta; Belongs to the integrin beta chain family. (810 aa)
ENSONIP00000067993Fibrillin-2 isoform X1. (551 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (817 aa)
LOC102075629Par-3 family cell polarity regulator beta b. (1201 aa)
I3IXF2_ORENIPeptidylprolyl isomerase. (119 aa)
LOC100705189Peptidylprolyl isomerase. (108 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
LOC100691730Prostate transmembrane protein, androgen induced 1. (325 aa)
I3KPC3_ORENIHomeobox domain-containing protein. (355 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1289 aa)
LOC100700558Mothers against decapentaplegic homolog. (550 aa)
meis1Meis homeobox 1 b. (387 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1023 aa)
LOC100697722Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
usp9xUbiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2612 aa)
LOC100690952Meis homeobox 2b. (431 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSONIP00000077937Partitioning defective 3 homolog B isoform X1. (70 aa)
LOC100693777Mothers against decapentaplegic homolog. (500 aa)
I3KQQ1_ORENISKI-like proto-oncogene a. (655 aa)
LOC100705673Homeobox domain-containing protein. (413 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
LOC100707272Iroquois homeobox 1a. (495 aa)
cgnCingulin a. (1202 aa)
LOC100694653Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
rnf111Ring finger protein 111. (1006 aa)
LOC100705578E2F_TDP domain-containing protein. (79 aa)
LOC100690458Transforming growth factor beta; Belongs to the TGF-beta family. (419 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1239 aa)
rbl1Retinoblastoma-like 1 (p107). (1064 aa)
LOC100703449Par-6 family cell polarity regulator alpha. (530 aa)
LOC100700916V-ski avian sarcoma viral oncogene homolog b. (687 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
PARD3Par-3 family cell polarity regulator. (1376 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (781 aa)
Irx3Iroquois homeobox 3a. (433 aa)
irx5Iroquois homeobox 5a. (456 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (343 aa)
ENSONIP00000001443annotation not available (1468 aa)
snw1SNW domain containing 1. (536 aa)
ccnkCyclin K; Belongs to the cyclin family. (550 aa)
LOC100692950Peptidylprolyl isomerase. (109 aa)
trim33Tripartite motif containing 33. (1216 aa)
STUB1STIP1 homology and U-box containing protein 1. (290 aa)
LOC100692645Uncharacterized protein. (863 aa)
Itgb8Integrin beta; Belongs to the integrin beta chain family. (834 aa)
ncor2Nuclear receptor corepressor 2. (2362 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1496 aa)
cdk19Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (492 aa)
LOC100699525Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
I3K1Z3_ORENIUncharacterized protein. (1603 aa)
LOC100709139Cyclin T2b; Belongs to the cyclin family. (610 aa)
I3K2K5_ORENIUncharacterized protein. (911 aa)
cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
strapSerine/threonine kinase receptor associated protein. (366 aa)
ncor1Nuclear receptor corepressor 1. (2351 aa)
LOC100712573Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
cdk8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (475 aa)
I3JLM4_ORENIIroquois homeobox 1b. (184 aa)
tfdp1Transcription factor. (413 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC100698856Par-3 family cell polarity regulator alpha, b. (1412 aa)
LOC100710008Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
smad3Mothers against decapentaplegic homolog. (448 aa)
LOC100710325Mothers against decapentaplegic homolog. (467 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC106098551Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (614 aa)
LOC100711982Iroquois homeobox 7. (386 aa)
LOC100710680Myeloid ecotropic viral integration site 3. (418 aa)
LOC100703104Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
Zfyve9Zinc finger, FYVE domain containing 9a. (1201 aa)
LOC100696648Mohawk homeobox b. (416 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (538 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
LOC100707881JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (297 aa)
FBN1Fibrillin 1. (2831 aa)
men1Multiple endocrine neoplasia I. (629 aa)
irx6Iroquois homeobox 6a. (498 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
LOC100703326Homeobox protein TGIF2. (578 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1644 aa)
LOC100690293Ubiquitin-NEDD8-like protein RUB2. (183 aa)
LOC100695177Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
LOC100699888STIP1 homology and U-Box containing protein 1. (284 aa)
ccnqCyclin Q; Belongs to the cyclin family. (211 aa)
e2f4E2F transcription factor 4. (407 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (740 aa)
I3KZC4_ORENIJunB proto-oncogene, AP-1 transcription factor subunit a. (300 aa)
LOC100711516Ubiquitin-like protein Nedd8. (95 aa)
LOC100707005Iroquois homeobox 4a. (473 aa)
LOC100698210Cyclin T2; Belongs to the cyclin family. (708 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
LOC100708381Mothers against decapentaplegic homolog. (526 aa)
LOC100690070Cyclin T1; Belongs to the cyclin family. (702 aa)
ccncCyclin C; Belongs to the cyclin family. (353 aa)
LOC100705046Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
LOC100710602Cingulin b. (1200 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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