STRINGSTRING
hsd17b12-2 hsd17b12-2 Srd5a3 Srd5a3 FADS6 FADS6 ENSONIP00000064555 ENSONIP00000064555 LOC100708840 LOC100708840 FDX1 FDX1 LOC100706564 LOC100706564 hsd17b3 hsd17b3 hsd17b12 hsd17b12 LOC100534568 LOC100534568 LOC100702165 LOC100702165 LOC100701114 LOC100701114 stard3nl stard3nl fdx2 fdx2 srd5a2 srd5a2 hsdl1 hsdl1 pomc pomc LOC100693336 LOC100693336 dhrs7c dhrs7c LOC100534501 LOC100534501 ENSONIP00000029541 ENSONIP00000029541 CYP19A1 CYP19A1 LOC100710599 LOC100710599 I3KE17_ORENI I3KE17_ORENI LOC100700843 LOC100700843 cyp17 cyp17 stard3 stard3 LOC100706723 LOC100706723 hsd17b1 hsd17b1 LOC100707265 LOC100707265 I3IZP7_ORENI I3IZP7_ORENI hsd11b2 hsd11b2 ENSONIP00000004776 ENSONIP00000004776 LOC100707266 LOC100707266 hsd17b14 hsd17b14 LOC100712102 LOC100712102 LOC100711421 LOC100711421 srd5a1 srd5a1 sdr16c5 sdr16c5 fdxr fdxr LOC100703376 LOC100703376 LOC100708217 LOC100708217 rdh8 rdh8 Tspo Tspo LOC100703009 LOC100703009 LOC100703825 LOC100703825 cyp17a2 cyp17a2 star star Rimbp2 Rimbp2 cyp11b cyp11b
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hsd17b12-2Hydroxysteroid (20-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (340 aa)
Srd5a33-oxo-5-alpha-steroid 4-dehydrogenase 3 / polyprenol reductase. (324 aa)
FADS6Fatty acid desaturase 6. (372 aa)
ENSONIP00000064555annotation not available (1504 aa)
LOC100708840Proopiomelanocortin. (216 aa)
FDX1Ferredoxin 1. (147 aa)
LOC100706564Uncharacterized protein. (280 aa)
hsd17b3Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa)
hsd17b12Hydroxysteroid (17-beta) dehydrogenase 12a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa)
LOC100534568Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family. (374 aa)
LOC100702165START domain-containing protein. (278 aa)
LOC100701114Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 1. (318 aa)
stard3nlSTARD3 N-terminal like. (235 aa)
fdx2Ferredoxin 2. (196 aa)
srd5a23-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (271 aa)
hsdl1Hydroxysteroid dehydrogenase like 1. (325 aa)
pomcUncharacterized protein. (208 aa)
LOC100693336Zgc:109982; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (315 aa)
dhrs7cDehydrogenase/reductase (SDR family) member 7Cb. (313 aa)
LOC100534501Luteinizing hormone, beta polypeptide. (145 aa)
ENSONIP00000029541annotation not available (253 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
LOC100710599Hydroxysteroid (11-beta) dehydrogenase 1-like a. (289 aa)
I3KE17_ORENICholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (579 aa)
LOC100700843Aldo-keto reductase family 1, member B1 (aldose reductase), tandem duplicate 2. (324 aa)
cyp17Cytochrome P450, family 17, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (520 aa)
stard3StAR-related lipid transfer (START) domain containing 3. (458 aa)
LOC100706723SERPIN domain-containing protein; Belongs to the serpin family. (407 aa)
hsd17b1Hydroxysteroid (17-beta) dehydrogenase 1. (289 aa)
LOC100707265Retinol dehydrogenase 8a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
I3IZP7_ORENIZmp:0000001048; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
hsd11b211-beta hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (406 aa)
ENSONIP00000004776annotation not available (985 aa)
LOC100707266Uncharacterized protein. (330 aa)
hsd17b14Hydroxysteroid (17-beta) dehydrogenase 14. (267 aa)
LOC100712102Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; Belongs to the serpin family. (404 aa)
LOC1007114213-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (251 aa)
srd5a13-oxo-5-alpha-steroid 4-dehydrogenase; Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology. (265 aa)
sdr16c5Short chain dehydrogenase/reductase family 16C, member 5a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (350 aa)
fdxrNADPH:adrenodoxin oxidoreductase, mitochondrial. (503 aa)
LOC100703376Cytochrome P450, family 21, subfamily A, polypeptide 2. (521 aa)
LOC100708217Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens. (534 aa)
rdh8Retinol dehydrogenase 8b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (339 aa)
TspoTranslocator protein. (182 aa)
LOC100703009Hydroxysteroid (11-beta) dehydrogenase 1-like a. (289 aa)
LOC100703825Hydroxysteroid (17-beta) dehydrogenase 12b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (324 aa)
cyp17a2Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family. (534 aa)
starSteroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (293 aa)
Rimbp2RIMS binding protein 2. (1656 aa)
cyp11bCytochrome P450, family 11, subfamily C, polypeptide 1; Belongs to the cytochrome P450 family. (538 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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