(42 nodes) A tetrasaccharide linker sequence is required for GAG synthesis network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100703873	Uncharacterized protein. (939 aa)
	SDC3	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (373 aa)
	dcn	Decorin; May affect the rate of fibrils formation. (359 aa)
	LOC102079339	Glypican 6b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (564 aa)
	ENSONIP00000079679	annotation not available (536 aa)
	I3J121_ORENI	Chondroitin sulfate proteoglycan 5b. (684 aa)
	LOC100712050	Brevican. (1235 aa)
	gpc2	Glypican 2; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (586 aa)
	b3gat2	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (321 aa)
	LOC100710496	Glypican 6a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (568 aa)
	LOC100710764	Glypican 5a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (569 aa)
	LOC100695963	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (306 aa)
	I3J8E6_ORENI	Uncharacterized protein. (2222 aa)
	b4galt7	Xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I). (320 aa)
	LOC100709321	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (359 aa)
	LOC102083201	Glypican 1a; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (543 aa)
	LOC100695765	Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (626 aa)
	LOC102077503	Glypican 5c; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (607 aa)
	LOC100695886	Glypican 1b; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (553 aa)
	LOC100704480	Uncharacterized protein. (1302 aa)
	ENSONIP00000015202	annotation not available (311 aa)
	bgn	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (371 aa)
	LOC100706927	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (216 aa)
	I3K9Y9_ORENI	Si:dkey-193c22.2. (2193 aa)
	LOC102075906	Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (583 aa)
	LOC100707936	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (211 aa)
	xylt1	Xylosyltransferase I. (942 aa)
	xylt2	Xylosyltransferase II. (867 aa)
	LOC100691206	Uncharacterized protein. (1568 aa)
	b3galt6	Hexosyltransferase. (339 aa)
	cspg4	Chondroitin sulfate proteoglycan 4. (2304 aa)
	agrn	Agrin. (2006 aa)
	I3JV43_ORENI	Uncharacterized protein. (2648 aa)
	b3gat3	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (368 aa)
	Cspg5	Chondroitin sulfate proteoglycan 5a. (625 aa)
	B3GAT1	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (344 aa)
	LOC112846392	Uncharacterized protein LOC112846392. (497 aa)
	LOC100695628	Neurocan core protein. (1358 aa)
	I3K257_ORENI	Uncharacterized protein. (364 aa)
	LOC100696204	Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (572 aa)
	ENSONIP00000063638	Uncharacterized protein LOC112847092. (162 aa)
	I3KII9_ORENI	Heparan sulfate proteoglycan 2. (3574 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B3GAT1	SDC3	ENSONIP00000043659	ENSONIP00000065898	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.405
B3GAT1	b3gat3	ENSONIP00000043659	ENSONIP00000033372	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.	0.505
I3J8E6_ORENI	I3KII9_ORENI	ENSONIP00000005136	ENSONIP00000064538	Uncharacterized protein.	Heparan sulfate proteoglycan 2.	0.450
I3J8E6_ORENI	LOC100691206	ENSONIP00000005136	ENSONIP00000024888	Uncharacterized protein.	Uncharacterized protein.	0.441
I3J8E6_ORENI	LOC100707936	ENSONIP00000005136	ENSONIP00000023363	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.401
I3J8E6_ORENI	LOC100712050	ENSONIP00000005136	ENSONIP00000001930	Uncharacterized protein.	Brevican.	0.441
I3J8E6_ORENI	agrn	ENSONIP00000005136	ENSONIP00000028345	Uncharacterized protein.	Agrin.	0.420
I3J8E6_ORENI	dcn	ENSONIP00000005136	ENSONIP00000066686	Uncharacterized protein.	Decorin; May affect the rate of fibrils formation.	0.516
I3JV43_ORENI	I3KII9_ORENI	ENSONIP00000028521	ENSONIP00000064538	Uncharacterized protein.	Heparan sulfate proteoglycan 2.	0.446
I3JV43_ORENI	LOC100691206	ENSONIP00000028521	ENSONIP00000024888	Uncharacterized protein.	Uncharacterized protein.	0.511
I3JV43_ORENI	LOC100712050	ENSONIP00000028521	ENSONIP00000001930	Uncharacterized protein.	Brevican.	0.511
I3JV43_ORENI	SDC3	ENSONIP00000028521	ENSONIP00000065898	Uncharacterized protein.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.479
I3JV43_ORENI	agrn	ENSONIP00000028521	ENSONIP00000028345	Uncharacterized protein.	Agrin.	0.447
I3K9Y9_ORENI	I3KII9_ORENI	ENSONIP00000017934	ENSONIP00000064538	Si:dkey-193c22.2.	Heparan sulfate proteoglycan 2.	0.450
I3K9Y9_ORENI	LOC100691206	ENSONIP00000017934	ENSONIP00000024888	Si:dkey-193c22.2.	Uncharacterized protein.	0.441
I3K9Y9_ORENI	LOC100707936	ENSONIP00000017934	ENSONIP00000023363	Si:dkey-193c22.2.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.401
I3K9Y9_ORENI	LOC100712050	ENSONIP00000017934	ENSONIP00000001930	Si:dkey-193c22.2.	Brevican.	0.441
I3K9Y9_ORENI	agrn	ENSONIP00000017934	ENSONIP00000028345	Si:dkey-193c22.2.	Agrin.	0.420
I3K9Y9_ORENI	dcn	ENSONIP00000017934	ENSONIP00000066686	Si:dkey-193c22.2.	Decorin; May affect the rate of fibrils formation.	0.516
I3KII9_ORENI	I3J8E6_ORENI	ENSONIP00000064538	ENSONIP00000005136	Heparan sulfate proteoglycan 2.	Uncharacterized protein.	0.450