(13 nodes) p75NTR recruits signalling complexes network (Oreochromis niloticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	irak1	Interleukin-1 receptor-associated kinase 1. (752 aa)
	sqstm1	Sequestosome 1. (436 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	prkci	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
	LOC100692989	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (296 aa)
	LOC100696124	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (232 aa)
	LOC100691074	Nerve growth factor receptor b. (430 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
	ripk2	Receptor-interacting serine-threonine kinase 2. (570 aa)
	I3IWI9_ORENI	Nerve growth factor receptor a (TNFR superfamily, member 16). (427 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	ikbkb	ENSONIP00000047919	ENSONIP00000051922	Ubiquitin B.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.637
ENSONIP00000047919	irak1	ENSONIP00000047919	ENSONIP00000070688	Ubiquitin B.	Interleukin-1 receptor-associated kinase 1.	0.659
ENSONIP00000047919	myd88	ENSONIP00000047919	ENSONIP00000007350	Ubiquitin B.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.473
ENSONIP00000047919	prkci	ENSONIP00000047919	ENSONIP00000023438	Ubiquitin B.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.623
ENSONIP00000047919	ripk2	ENSONIP00000047919	ENSONIP00000057830	Ubiquitin B.	Receptor-interacting serine-threonine kinase 2.	0.525
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	sqstm1	ENSONIP00000047919	ENSONIP00000000126	Ubiquitin B.	Sequestosome 1.	0.954
ENSONIP00000047919	traf6	ENSONIP00000047919	ENSONIP00000057481	Ubiquitin B.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.959
I3IWI9_ORENI	LOC100691074	ENSONIP00000074675	ENSONIP00000041976	Nerve growth factor receptor a (TNFR superfamily, member 16).	Nerve growth factor receptor b.	0.907
I3IWI9_ORENI	LOC100692989	ENSONIP00000074675	ENSONIP00000025849	Nerve growth factor receptor a (TNFR superfamily, member 16).	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.998
I3IWI9_ORENI	LOC100696124	ENSONIP00000074675	ENSONIP00000026281	Nerve growth factor receptor a (TNFR superfamily, member 16).	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.	0.936
I3IWI9_ORENI	ikbkb	ENSONIP00000074675	ENSONIP00000051922	Nerve growth factor receptor a (TNFR superfamily, member 16).	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.563
I3IWI9_ORENI	irak1	ENSONIP00000074675	ENSONIP00000070688	Nerve growth factor receptor a (TNFR superfamily, member 16).	Interleukin-1 receptor-associated kinase 1.	0.753
I3IWI9_ORENI	myd88	ENSONIP00000074675	ENSONIP00000007350	Nerve growth factor receptor a (TNFR superfamily, member 16).	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.652
I3IWI9_ORENI	prkci	ENSONIP00000074675	ENSONIP00000023438	Nerve growth factor receptor a (TNFR superfamily, member 16).	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.528
I3IWI9_ORENI	ripk2	ENSONIP00000074675	ENSONIP00000057830	Nerve growth factor receptor a (TNFR superfamily, member 16).	Receptor-interacting serine-threonine kinase 2.	0.929
I3IWI9_ORENI	sqstm1	ENSONIP00000074675	ENSONIP00000000126	Nerve growth factor receptor a (TNFR superfamily, member 16).	Sequestosome 1.	0.664
I3IWI9_ORENI	traf6	ENSONIP00000074675	ENSONIP00000057481	Nerve growth factor receptor a (TNFR superfamily, member 16).	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.866
LOC100691074	I3IWI9_ORENI	ENSONIP00000041976	ENSONIP00000074675	Nerve growth factor receptor b.	Nerve growth factor receptor a (TNFR superfamily, member 16).	0.907
LOC100691074	LOC100692989	ENSONIP00000041976	ENSONIP00000025849	Nerve growth factor receptor b.	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family.	0.983