49 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100692950	Peptidylprolyl isomerase. (109 aa)
	ENSONIP00000001443	annotation not available (1468 aa)
	itgb6	Integrin beta; Belongs to the integrin beta chain family. (781 aa)
	bambi	BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1239 aa)
	LOC100690458	Transforming growth factor beta; Belongs to the TGF-beta family. (419 aa)
	LOC100694653	Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	STUB1	STIP1 homology and U-box containing protein 1. (290 aa)
	LOC100692645	Uncharacterized protein. (863 aa)
	Itgb8	Integrin beta; Belongs to the integrin beta chain family. (834 aa)
	ltbp1	Latent transforming growth factor beta binding protein 1. (1496 aa)
	LOC100699525	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
	I3K1Z3_ORENI	Uncharacterized protein. (1603 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	strap	Serine/threonine kinase receptor associated protein. (366 aa)
	LOC100712573	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	LOC100710008	Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
	smad3	Mothers against decapentaplegic homolog. (448 aa)
	LOC100710325	Mothers against decapentaplegic homolog. (467 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC106098551	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (614 aa)
	Zfyve9	Zinc finger, FYVE domain containing 9a. (1201 aa)
	TGFBR2	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (538 aa)
	tgfb3	Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
	ldlrad4	Low density lipoprotein receptor class A domain containing 4b. (297 aa)
	FBN1	Fibrillin 1. (2831 aa)
	tgfb2	Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
	LOC100690293	Ubiquitin-NEDD8-like protein RUB2. (183 aa)
	LOC100695177	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
	LOC100699888	STIP1 homology and U-Box containing protein 1. (284 aa)
	LOC100711516	Ubiquitin-like protein Nedd8. (95 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	LOC100708381	Mothers against decapentaplegic homolog. (526 aa)
	LOC100705046	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
	I3JG35_ORENI	Cbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
	itgb3	Integrin beta; Belongs to the integrin beta chain family. (844 aa)
	LOC100705094	Mothers against decapentaplegic homolog. (765 aa)
	LOC100699105	Integrin beta; Belongs to the integrin beta chain family. (810 aa)
	ENSONIP00000067993	Fibrillin-2 isoform X1. (551 aa)
	Itgb5	Integrin beta; Belongs to the integrin beta chain family. (817 aa)
	I3IXF2_ORENI	Peptidylprolyl isomerase. (119 aa)
	LOC100705189	Peptidylprolyl isomerase. (108 aa)
	LOC100691730	Prostate transmembrane protein, androgen induced 1. (325 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	LOC100700558	Mothers against decapentaplegic homolog. (550 aa)
	LOC100693777	Mothers against decapentaplegic homolog. (500 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000001443	Itgb8	ENSONIP00000001443	ENSONIP00000013660	annotation not available	Integrin beta; Belongs to the integrin beta chain family.	0.488
ENSONIP00000001443	LOC100690458	ENSONIP00000001443	ENSONIP00000006772	annotation not available	Transforming growth factor beta; Belongs to the TGF-beta family.	0.577
ENSONIP00000001443	LOC100694653	ENSONIP00000001443	ENSONIP00000007415	annotation not available	Transforming growth factor beta; Belongs to the TGF-beta family.	0.774
ENSONIP00000001443	LOC100710008	ENSONIP00000001443	ENSONIP00000019232	annotation not available	Transforming growth factor beta; Belongs to the TGF-beta family.	0.576
ENSONIP00000001443	itgb6	ENSONIP00000001443	ENSONIP00000004172	annotation not available	Integrin beta; Belongs to the integrin beta chain family.	0.556
ENSONIP00000001443	tgfb2	ENSONIP00000001443	ENSONIP00000035731	annotation not available	Transforming growth factor beta; Belongs to the TGF-beta family.	0.577
ENSONIP00000001443	tgfb3	ENSONIP00000001443	ENSONIP00000025436	annotation not available	Transforming growth factor beta; Belongs to the TGF-beta family.	0.576
ENSONIP00000047919	I3JG35_ORENI	ENSONIP00000047919	ENSONIP00000059356	Ubiquitin B.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100690293	ENSONIP00000047919	ENSONIP00000036290	Ubiquitin B.	Ubiquitin-NEDD8-like protein RUB2.	0.824
ENSONIP00000047919	LOC100692645	ENSONIP00000047919	ENSONIP00000011884	Ubiquitin B.	Uncharacterized protein.	0.768
ENSONIP00000047919	LOC100693777	ENSONIP00000047919	ENSONIP00000079463	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	LOC100694653	ENSONIP00000047919	ENSONIP00000007415	Ubiquitin B.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.659
ENSONIP00000047919	LOC100695177	ENSONIP00000047919	ENSONIP00000037654	Ubiquitin B.	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.479
ENSONIP00000047919	LOC100699525	ENSONIP00000047919	ENSONIP00000014371	Ubiquitin B.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100699888	ENSONIP00000047919	ENSONIP00000037753	Ubiquitin B.	STIP1 homology and U-Box containing protein 1.	0.720
ENSONIP00000047919	LOC100700558	ENSONIP00000047919	ENSONIP00000072817	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100705094	ENSONIP00000047919	ENSONIP00000065453	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100708381	ENSONIP00000047919	ENSONIP00000050523	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100710325	ENSONIP00000047919	ENSONIP00000020038	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	LOC100711516	ENSONIP00000047919	ENSONIP00000041372	Ubiquitin B.	Ubiquitin-like protein Nedd8.	0.818