64 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
	LOC100709139	Cyclin T2b; Belongs to the cyclin family. (610 aa)
	cdk19	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (492 aa)
	ncor2	Nuclear receptor corepressor 2. (2362 aa)
	trim33	Tripartite motif containing 33. (1216 aa)
	I3JLM4_ORENI	Iroquois homeobox 1b. (184 aa)
	LOC100705673	Homeobox domain-containing protein. (413 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	LOC100707272	Iroquois homeobox 1a. (495 aa)
	rnf111	Ring finger protein 111. (1006 aa)
	LOC100705578	E2F_TDP domain-containing protein. (79 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1064 aa)
	LOC100700916	V-ski avian sarcoma viral oncogene homolog b. (687 aa)
	Irx3	Iroquois homeobox 3a. (433 aa)
	ccnk	Cyclin K; Belongs to the cyclin family. (550 aa)
	snw1	SNW domain containing 1. (536 aa)
	atp1b4	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (343 aa)
	mkx	Mohawk homeobox a. (375 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
	LOC100705046	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
	ccnc	Cyclin C; Belongs to the cyclin family. (353 aa)
	LOC100690070	Cyclin T1; Belongs to the cyclin family. (702 aa)
	LOC100708381	Mothers against decapentaplegic homolog. (526 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	LOC100698210	Cyclin T2; Belongs to the cyclin family. (708 aa)
	LOC100707005	Iroquois homeobox 4a. (473 aa)
	I3KZC4_ORENI	JunB proto-oncogene, AP-1 transcription factor subunit a. (300 aa)
	ski	V-ski avian sarcoma viral oncogene homolog a. (740 aa)
	e2f4	E2F transcription factor 4. (407 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (211 aa)
	LOC100703326	Homeobox protein TGIF2. (578 aa)
	irx6	Iroquois homeobox 6a. (498 aa)
	men1	Multiple endocrine neoplasia I. (629 aa)
	LOC100707881	JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
	LOC100696648	Mohawk homeobox b. (416 aa)
	LOC100710680	Myeloid ecotropic viral integration site 3. (418 aa)
	LOC100711982	Iroquois homeobox 7. (386 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC100710325	Mothers against decapentaplegic homolog. (467 aa)
	smad3	Mothers against decapentaplegic homolog. (448 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	tfdp1	Transcription factor. (413 aa)
	irx5	Iroquois homeobox 5a. (456 aa)
	cdk8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (475 aa)
	ncor1	Nuclear receptor corepressor 1. (2351 aa)
	I3KQQ1_ORENI	SKI-like proto-oncogene a. (655 aa)
	LOC100693777	Mothers against decapentaplegic homolog. (500 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC100690952	Meis homeobox 2b. (431 aa)
	usp9x	Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2612 aa)
	LOC100697722	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1023 aa)
	meis1	Meis homeobox 1 b. (387 aa)
	LOC100700558	Mothers against decapentaplegic homolog. (550 aa)
	nedd4l	NEDD4 like E3 ubiquitin protein ligase. (1289 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	I3KPC3_ORENI	Homeobox domain-containing protein. (355 aa)
	meis2	Meis homeobox 2a. (480 aa)
	LOC100705094	Mothers against decapentaplegic homolog. (765 aa)
	sp1	Sp1 transcription factor. (726 aa)
	irx2	Iroquois homeobox 2a. (511 aa)
	I3JI97_ORENI	Homeobox domain-containing protein. (416 aa)
	LOC100705918	TGFB-induced factor homeobox 1. (330 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	I3KQQ1_ORENI	ENSONIP00000047919	ENSONIP00000080879	Ubiquitin B.	SKI-like proto-oncogene a.	0.631
ENSONIP00000047919	LOC100693777	ENSONIP00000047919	ENSONIP00000079463	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	LOC100700558	ENSONIP00000047919	ENSONIP00000072817	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100700916	ENSONIP00000047919	ENSONIP00000004957	Ubiquitin B.	V-ski avian sarcoma viral oncogene homolog b.	0.532
ENSONIP00000047919	LOC100705094	ENSONIP00000047919	ENSONIP00000065453	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100708381	ENSONIP00000047919	ENSONIP00000050523	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100710325	ENSONIP00000047919	ENSONIP00000020038	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	SMAD3	ENSONIP00000047919	ENSONIP00000071836	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	kxd1	ENSONIP00000047919	ENSONIP00000018629	Ubiquitin B.	KxDL motif containing 1.	0.717
ENSONIP00000047919	ncor1	ENSONIP00000047919	ENSONIP00000016143	Ubiquitin B.	Nuclear receptor corepressor 1.	0.552
ENSONIP00000047919	ncor2	ENSONIP00000047919	ENSONIP00000013833	Ubiquitin B.	Nuclear receptor corepressor 2.	0.552
ENSONIP00000047919	nedd4l	ENSONIP00000047919	ENSONIP00000072135	Ubiquitin B.	NEDD4 like E3 ubiquitin protein ligase.	0.800
ENSONIP00000047919	parp1	ENSONIP00000047919	ENSONIP00000074983	Ubiquitin B.	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.	0.634
ENSONIP00000047919	rbl1	ENSONIP00000047919	ENSONIP00000006602	Ubiquitin B.	Retinoblastoma-like 1 (p107).	0.697
ENSONIP00000047919	rnf111	ENSONIP00000047919	ENSONIP00000007363	Ubiquitin B.	Ring finger protein 111.	0.779
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	ski	ENSONIP00000047919	ENSONIP00000039122	Ubiquitin B.	V-ski avian sarcoma viral oncogene homolog a.	0.626
ENSONIP00000047919	smad3	ENSONIP00000047919	ENSONIP00000019456	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	smad7	ENSONIP00000047919	ENSONIP00000009762	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.489
ENSONIP00000047919	trim33	ENSONIP00000047919	ENSONIP00000011616	Ubiquitin B.	Tripartite motif containing 33.	0.552