34 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ccnk	Cyclin K; Belongs to the cyclin family. (550 aa)
	rbl1	Retinoblastoma-like 1 (p107). (1064 aa)
	LOC100705578	E2F_TDP domain-containing protein. (79 aa)
	rnf111	Ring finger protein 111. (1006 aa)
	smad7	Mothers against decapentaplegic homolog. (376 aa)
	cdk19	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (492 aa)
	LOC100709139	Cyclin T2b; Belongs to the cyclin family. (610 aa)
	cdk9	Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	cdk8	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (475 aa)
	tfdp1	Transcription factor. (413 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	smad3	Mothers against decapentaplegic homolog. (448 aa)
	LOC100710325	Mothers against decapentaplegic homolog. (467 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC100707881	JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
	men1	Multiple endocrine neoplasia I. (629 aa)
	ccnq	Cyclin Q; Belongs to the cyclin family. (211 aa)
	e2f4	E2F transcription factor 4. (407 aa)
	I3KZC4_ORENI	JunB proto-oncogene, AP-1 transcription factor subunit a. (300 aa)
	LOC100698210	Cyclin T2; Belongs to the cyclin family. (708 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	LOC100708381	Mothers against decapentaplegic homolog. (526 aa)
	LOC100690070	Cyclin T1; Belongs to the cyclin family. (702 aa)
	ccnc	Cyclin C; Belongs to the cyclin family. (353 aa)
	LOC100705046	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
	sp1	Sp1 transcription factor. (726 aa)
	LOC100705094	Mothers against decapentaplegic homolog. (765 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	LOC100700558	Mothers against decapentaplegic homolog. (550 aa)
	LOC100697722	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC100693777	Mothers against decapentaplegic homolog. (500 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	LOC100693777	ENSONIP00000047919	ENSONIP00000079463	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	LOC100700558	ENSONIP00000047919	ENSONIP00000072817	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100705094	ENSONIP00000047919	ENSONIP00000065453	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100708381	ENSONIP00000047919	ENSONIP00000050523	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.562
ENSONIP00000047919	LOC100710325	ENSONIP00000047919	ENSONIP00000020038	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	SMAD3	ENSONIP00000047919	ENSONIP00000071836	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	kxd1	ENSONIP00000047919	ENSONIP00000018629	Ubiquitin B.	KxDL motif containing 1.	0.717
ENSONIP00000047919	rbl1	ENSONIP00000047919	ENSONIP00000006602	Ubiquitin B.	Retinoblastoma-like 1 (p107).	0.697
ENSONIP00000047919	rnf111	ENSONIP00000047919	ENSONIP00000007363	Ubiquitin B.	Ring finger protein 111.	0.779
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	smad3	ENSONIP00000047919	ENSONIP00000019456	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.482
ENSONIP00000047919	smad7	ENSONIP00000047919	ENSONIP00000009762	Ubiquitin B.	Mothers against decapentaplegic homolog.	0.489
ENSONIP00000047919	uba52	ENSONIP00000047919	ENSONIP00000016035	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997
LOC100690070	LOC100700558	ENSONIP00000050688	ENSONIP00000072817	Cyclin T1; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.401
LOC100690070	LOC100705094	ENSONIP00000050688	ENSONIP00000065453	Cyclin T1; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.401
LOC100690070	LOC100708381	ENSONIP00000050688	ENSONIP00000050523	Cyclin T1; Belongs to the cyclin family.	Mothers against decapentaplegic homolog.	0.401
LOC100690070	ccnc	ENSONIP00000050688	ENSONIP00000050925	Cyclin T1; Belongs to the cyclin family.	Cyclin C; Belongs to the cyclin family.	0.674
LOC100690070	ccnk	ENSONIP00000050688	ENSONIP00000001356	Cyclin T1; Belongs to the cyclin family.	Cyclin K; Belongs to the cyclin family.	0.657
LOC100690070	cdk19	ENSONIP00000050688	ENSONIP00000014337	Cyclin T1; Belongs to the cyclin family.	Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily.	0.571
LOC100690070	cdk8	ENSONIP00000050688	ENSONIP00000017757	Cyclin T1; Belongs to the cyclin family.	Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily.	0.571