(38 nodes) The canonical retinoid cycle in rods (twilight vision) network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100710942	Rhodopsin. (352 aa)
	LOC100704704	LRAT domain-containing protein. (213 aa)
	I3JB77_ORENI	ATP-binding cassette, sub-family A (ABC1), member 4a. (2308 aa)
	rbp4	Retinol binding protein 4, plasma; Belongs to the calycin superfamily. Lipocalin family. (266 aa)
	ENSONIP00000069473	Interphotoreceptor retinoid-binding protein like. (623 aa)
	I3IYS8_ORENI	Myosin VIIAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2109 aa)
	I3J8V1_ORENI	Rhodopsin. (374 aa)
	Rbp3	Retinol-binding protein 3. (620 aa)
	LOC100706558	Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
	LOC100694376	Retinoid isomerohydrolase RPE65 b. (550 aa)
	LOC100702412	Retinoid isomerohydrolase RPE65 a. (541 aa)
	LOC100698328	Apolipoprotein Da, duplicate 2; Belongs to the calycin superfamily. Lipocalin family. (195 aa)
	LOC100693385	Retinaldehyde binding protein 1a. (316 aa)
	LOC100711209	Rhodopsin. (352 aa)
	LOC100703355	Cytochrome P450, family 4, subfamily V, polypeptide 8; Belongs to the cytochrome P450 family. (533 aa)
	LOC100699208	Retinol dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (337 aa)
	I3KQB3_ORENI	ATP-binding cassette, sub-family A (ABC1), member 4b. (2288 aa)
	LOC100703897	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa)
	LOC100691236	Rhodopsin. (354 aa)
	Smpdl3a	Sphingomyelin phosphodiesterase, acid-like 3A. (452 aa)
	plekhd1	Pleckstrin homology domain containing, family D (with coiled-coil domains) member 1. (501 aa)
	Rdh12	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (322 aa)
	LOC100693144	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (335 aa)
	I3KQW1_ORENI	Patched domain containing 3. (453 aa)
	RHO	Rhodopsin. (351 aa)
	I3KEW7_ORENI	Retinaldehyde binding protein 1b. (332 aa)
	stra6	Stimulated by retinoic acid 6. (658 aa)
	rdh10	Retinol dehydrogenase 10a; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (340 aa)
	LOC100692598	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
	napepld	N-acyl phosphatidylethanolamine phospholipase D. (398 aa)
	I3JVB1_ORENI	Lecithin retinol acyltransferase a. (228 aa)
	I3JT13_ORENI	Myosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2181 aa)
	LOC100705499	Dehydrogenase/reductase (SDR family) member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa)
	LOC100703294	Uncharacterized protein. (677 aa)
	rdh5	Retinol dehydrogenase 5 (11-cis/9-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
	ptchd4	Patched domain containing 4. (925 aa)
	ptchd1	Patched domain containing 1. (986 aa)
	PTCHD3	Patched domain containing 3. (852 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000069473	I3J8V1_ORENI	ENSONIP00000069473	ENSONIP00000062452	Interphotoreceptor retinoid-binding protein like.	Rhodopsin.	0.465
ENSONIP00000069473	LOC100691236	ENSONIP00000069473	ENSONIP00000026444	Interphotoreceptor retinoid-binding protein like.	Rhodopsin.	0.465
ENSONIP00000069473	LOC100710942	ENSONIP00000069473	ENSONIP00000005293	Interphotoreceptor retinoid-binding protein like.	Rhodopsin.	0.465
ENSONIP00000069473	LOC100711209	ENSONIP00000069473	ENSONIP00000038479	Interphotoreceptor retinoid-binding protein like.	Rhodopsin.	0.465
ENSONIP00000069473	RHO	ENSONIP00000069473	ENSONIP00000021720	Interphotoreceptor retinoid-binding protein like.	Rhodopsin.	0.465
I3J8V1_ORENI	ENSONIP00000069473	ENSONIP00000062452	ENSONIP00000069473	Rhodopsin.	Interphotoreceptor retinoid-binding protein like.	0.465
I3J8V1_ORENI	Rbp3	ENSONIP00000062452	ENSONIP00000060084	Rhodopsin.	Retinol-binding protein 3.	0.465
I3J8V1_ORENI	rdh5	ENSONIP00000062452	ENSONIP00000008634	Rhodopsin.	Retinol dehydrogenase 5 (11-cis/9-cis); Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.614
I3JB77_ORENI	I3KQB3_ORENI	ENSONIP00000079988	ENSONIP00000033668	ATP-binding cassette, sub-family A (ABC1), member 4a.	ATP-binding cassette, sub-family A (ABC1), member 4b.	0.901
I3JT13_ORENI	LOC100694376	ENSONIP00000012008	ENSONIP00000053807	Myosin VIIAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Retinoid isomerohydrolase RPE65 b.	0.466
I3JVB1_ORENI	LOC100693144	ENSONIP00000012806	ENSONIP00000023885	Lecithin retinol acyltransferase a.	Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.923
I3JVB1_ORENI	LOC100694376	ENSONIP00000012806	ENSONIP00000053807	Lecithin retinol acyltransferase a.	Retinoid isomerohydrolase RPE65 b.	0.922
I3JVB1_ORENI	LOC100699208	ENSONIP00000012806	ENSONIP00000034642	Lecithin retinol acyltransferase a.	Retinol dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.917
I3JVB1_ORENI	LOC100702412	ENSONIP00000012806	ENSONIP00000051302	Lecithin retinol acyltransferase a.	Retinoid isomerohydrolase RPE65 a.	0.922
I3JVB1_ORENI	LOC100703294	ENSONIP00000012806	ENSONIP00000008974	Lecithin retinol acyltransferase a.	Uncharacterized protein.	0.420
I3JVB1_ORENI	LOC100703897	ENSONIP00000012806	ENSONIP00000028480	Lecithin retinol acyltransferase a.	Retinol dehydrogenase 20; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.923
I3JVB1_ORENI	LOC100704704	ENSONIP00000012806	ENSONIP00000080147	Lecithin retinol acyltransferase a.	LRAT domain-containing protein.	0.902
I3JVB1_ORENI	LOC100705499	ENSONIP00000012806	ENSONIP00000011092	Lecithin retinol acyltransferase a.	Dehydrogenase/reductase (SDR family) member 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.712
I3JVB1_ORENI	Rdh12	ENSONIP00000012806	ENSONIP00000024708	Lecithin retinol acyltransferase a.	Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.679
I3JVB1_ORENI	rdh10	ENSONIP00000012806	ENSONIP00000017975	Lecithin retinol acyltransferase a.	Retinol dehydrogenase 10a; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.923