55 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rcor1	REST corepressor 1. (451 aa)
	LOC100704673	WD repeat domain 26b. (699 aa)
	LOC100691440	BRMS1 like transcriptional repressor b. (324 aa)
	wdr73	WD repeat domain 73. (384 aa)
	rest	RE1-silencing transcription factor. (973 aa)
	LOC100694214	GATA zinc finger domain containing 2Ab. (649 aa)
	hmg20b	High mobility group 20B. (294 aa)
	LOC100704896	Histone H2A; Belongs to the histone H2A family. (220 aa)
	LOC100705962	Chromodomain helicase DNA binding protein 4a. (1970 aa)
	LOC100691799	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	LOC100711924	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	hdac10	Histone deacetylase 10. (673 aa)
	LOC100698867	Chromodomain helicase DNA binding protein 3. (1822 aa)
	LOC100696317	Histone H2B; Belongs to the histone H2B family. (116 aa)
	ENSONIP00000012427	Autoimmune regulator. (369 aa)
	I3JV04_ORENI	Translocase of outer mitochondrial membrane 20. (1232 aa)
	LOC100705552	GATA zinc finger domain containing 2A. (735 aa)
	gatad2b	GATA zinc finger domain containing 2B. (653 aa)
	ncor2	Nuclear receptor corepressor 2. (2362 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (490 aa)
	sap18	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (153 aa)
	chd4	Uncharacterized protein. (1977 aa)
	sap30l	Sap30-like. (178 aa)
	LOC100695351	Retinoblastoma binding protein 4, like. (479 aa)
	I3JKL2_ORENI	Histone H2B; Belongs to the histone H2B family. (249 aa)
	I3KGS0_ORENI	REST corepressor 3. (527 aa)
	I3KPA0_ORENI	PHD finger protein 21Ab. (726 aa)
	ENSONIP00000024544	annotation not available (265 aa)
	LOC109203640	Histone H2A; Belongs to the histone H2A family. (166 aa)
	hdac3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (431 aa)
	mta2	Metastasis associated 1 family, member 2. (667 aa)
	PHF21B	PHD finger protein 21B. (384 aa)
	arid4a	AT rich interactive domain 4A (RBP1-like). (1391 aa)
	LOC100706337	WD_REPEATS_REGION domain-containing protein. (441 aa)
	LOC100701651	Histone H2A; Belongs to the histone H2A family. (150 aa)
	hmg20a	High mobility group 20A. (303 aa)
	ENSONIP00000040408	annotation not available (127 aa)
	Brms1l	Uncharacterized protein. (262 aa)
	hdac8	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (395 aa)
	LOC100696254	Metastasis associated 1 family, member 3. (700 aa)
	rcor2	REST corepressor 2. (575 aa)
	chd5	Chromodomain helicase DNA binding protein 5. (2000 aa)
	Kdm1a	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (864 aa)
	Mta1	Metastasis associated 1. (764 aa)
	LOC100693699	Histone H2A; Belongs to the histone H2A family. (136 aa)
	tbl1x	Transducin beta like 1 X-linked. (554 aa)
	LOC100689862	Histone H2B 1/2. (124 aa)
	ENSONIP00000067435	annotation not available (108 aa)
	LOC100711479	Retinoblastoma binding protein 4. (449 aa)
	ENSONIP00000070717	annotation not available (111 aa)
	ENSONIP00000073881	annotation not available (231 aa)
	suds3	SDS3 homolog, SIN3A corepressor complex component. (318 aa)
	I3KI64_ORENI	WD repeat domain 26a. (670 aa)
	LOC100689862-2	Histone H2B 1/2. (124 aa)
	I3K790_ORENI	BRMS1 transcriptional repressor and anoikis regulator. (320 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Brms1l	HDAC2	ENSONIP00000043323	ENSONIP00000014285	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.733
Brms1l	I3JV04_ORENI	ENSONIP00000043323	ENSONIP00000012699	Uncharacterized protein.	Translocase of outer mitochondrial membrane 20.	0.978
Brms1l	I3KGS0_ORENI	ENSONIP00000043323	ENSONIP00000020315	Uncharacterized protein.	REST corepressor 3.	0.426
Brms1l	I3KI64_ORENI	ENSONIP00000043323	ENSONIP00000075894	Uncharacterized protein.	WD repeat domain 26a.	0.471
Brms1l	LOC100691799	ENSONIP00000043323	ENSONIP00000009730	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.736
Brms1l	LOC100695351	ENSONIP00000043323	ENSONIP00000079377	Uncharacterized protein.	Retinoblastoma binding protein 4, like.	0.668
Brms1l	LOC100696254	ENSONIP00000043323	ENSONIP00000045614	Uncharacterized protein.	Metastasis associated 1 family, member 3.	0.447
Brms1l	LOC100704673	ENSONIP00000043323	ENSONIP00000000744	Uncharacterized protein.	WD repeat domain 26b.	0.471
Brms1l	LOC100706337	ENSONIP00000043323	ENSONIP00000038174	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.668
Brms1l	LOC100711479	ENSONIP00000043323	ENSONIP00000070642	Uncharacterized protein.	Retinoblastoma binding protein 4.	0.668
Brms1l	LOC100711924	ENSONIP00000043323	ENSONIP00000010308	Uncharacterized protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.736
Brms1l	Mta1	ENSONIP00000043323	ENSONIP00000051134	Uncharacterized protein.	Metastasis associated 1.	0.447
Brms1l	arid4a	ENSONIP00000043323	ENSONIP00000036931	Uncharacterized protein.	AT rich interactive domain 4A (RBP1-like).	0.978
Brms1l	hdac10	ENSONIP00000043323	ENSONIP00000011058	Uncharacterized protein.	Histone deacetylase 10.	0.543
Brms1l	hdac3	ENSONIP00000043323	ENSONIP00000029435	Uncharacterized protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.737
Brms1l	hdac8	ENSONIP00000043323	ENSONIP00000045162	Uncharacterized protein.	Histone deacetylase 8; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.733
Brms1l	mta2	ENSONIP00000043323	ENSONIP00000031611	Uncharacterized protein.	Metastasis associated 1 family, member 2.	0.447
Brms1l	rcor1	ENSONIP00000043323	ENSONIP00000078628	Uncharacterized protein.	REST corepressor 1.	0.426
Brms1l	rcor2	ENSONIP00000043323	ENSONIP00000047053	Uncharacterized protein.	REST corepressor 2.	0.426
Brms1l	sap18	ENSONIP00000043323	ENSONIP00000015028	Uncharacterized protein.	Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins.	0.685