STRINGSTRING
fzd5 fzd5 rspo2 rspo2 fzd6 fzd6 usp8 usp8 lgr4 lgr4 fzd4 fzd4 lrp4 lrp4 Rspo3 Rspo3 LGR6 LGR6 lrtm1 lrtm1 uba52 uba52 LOC100698585 LOC100698585 rps27a rps27a Rspo1 Rspo1 LGR5 LGR5 fzd8 fzd8 wnt3a wnt3a Znrf3 Znrf3 lrp5 lrp5 ENSONIP00000047919 ENSONIP00000047919 LOC100705426 LOC100705426 Rnf43 Rnf43 LOC100692626 LOC100692626
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fzd5Frizzled 5/8. (576 aa)
rspo2R-spondin 2. (245 aa)
fzd6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (698 aa)
usp8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (931 aa)
lgr4Leucine-rich repeat containing G protein-coupled receptor 4. (978 aa)
fzd4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
lrp4Low density lipoprotein receptor-related protein 4. (1902 aa)
Rspo3R-spondin 3. (332 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (937 aa)
lrtm1Leucine rich repeats and transmembrane domains 1. (381 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC100698585Frizzled 5/8. (581 aa)
rps27aRibosomal protein S27a. (156 aa)
Rspo1R-spondin 1. (280 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (939 aa)
fzd8Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
Znrf3Zinc and ring finger 3. (883 aa)
lrp5Low density lipoprotein receptor-related protein 5. (1603 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
LOC100705426Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1617 aa)
Rnf43E3 ubiquitin-protein ligase RNF43. (817 aa)
LOC100692626Uncharacterized protein. (256 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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