23 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fzd5	Frizzled 5/8. (576 aa)
	rspo2	R-spondin 2. (245 aa)
	fzd6	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (698 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (931 aa)
	lgr4	Leucine-rich repeat containing G protein-coupled receptor 4. (978 aa)
	fzd4	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (533 aa)
	lrp4	Low density lipoprotein receptor-related protein 4. (1902 aa)
	Rspo3	R-spondin 3. (332 aa)
	LGR6	Leucine rich repeat containing G protein-coupled receptor 6. (937 aa)
	lrtm1	Leucine rich repeats and transmembrane domains 1. (381 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC100698585	Frizzled 5/8. (581 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	Rspo1	R-spondin 1. (280 aa)
	LGR5	Leucine rich repeat containing G protein-coupled receptor 5. (939 aa)
	fzd8	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
	wnt3a	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	Znrf3	Zinc and ring finger 3. (883 aa)
	lrp5	Low density lipoprotein receptor-related protein 5. (1603 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	LOC100705426	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1617 aa)
	Rnf43	E3 ubiquitin-protein ligase RNF43. (817 aa)
	LOC100692626	Uncharacterized protein. (256 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	LGR5	ENSONIP00000047919	ENSONIP00000022753	Ubiquitin B.	Leucine rich repeat containing G protein-coupled receptor 5.	0.509
ENSONIP00000047919	LOC100698585	ENSONIP00000047919	ENSONIP00000069979	Ubiquitin B.	Frizzled 5/8.	0.481
ENSONIP00000047919	Rnf43	ENSONIP00000047919	ENSONIP00000051519	Ubiquitin B.	E3 ubiquitin-protein ligase RNF43.	0.679
ENSONIP00000047919	Rspo3	ENSONIP00000047919	ENSONIP00000009097	Ubiquitin B.	R-spondin 3.	0.601
ENSONIP00000047919	Znrf3	ENSONIP00000047919	ENSONIP00000041572	Ubiquitin B.	Zinc and ring finger 3.	0.606
ENSONIP00000047919	fzd4	ENSONIP00000047919	ENSONIP00000006434	Ubiquitin B.	Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.	0.649
ENSONIP00000047919	fzd5	ENSONIP00000047919	ENSONIP00000066851	Ubiquitin B.	Frizzled 5/8.	0.481
ENSONIP00000047919	fzd6	ENSONIP00000047919	ENSONIP00000000169	Ubiquitin B.	Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.	0.563
ENSONIP00000047919	fzd8	ENSONIP00000047919	ENSONIP00000025946	Ubiquitin B.	Frizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family.	0.481
ENSONIP00000047919	lgr4	ENSONIP00000047919	ENSONIP00000003722	Ubiquitin B.	Leucine-rich repeat containing G protein-coupled receptor 4.	0.509
ENSONIP00000047919	lrtm1	ENSONIP00000047919	ENSONIP00000015621	Ubiquitin B.	Leucine rich repeats and transmembrane domains 1.	0.514
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	uba52	ENSONIP00000047919	ENSONIP00000016035	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997
ENSONIP00000047919	usp8	ENSONIP00000047919	ENSONIP00000000240	Ubiquitin B.	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family.	0.949
LGR5	ENSONIP00000047919	ENSONIP00000022753	ENSONIP00000047919	Leucine rich repeat containing G protein-coupled receptor 5.	Ubiquitin B.	0.509
LGR5	LGR6	ENSONIP00000022753	ENSONIP00000015531	Leucine rich repeat containing G protein-coupled receptor 5.	Leucine rich repeat containing G protein-coupled receptor 6.	0.927
LGR5	LOC100692626	ENSONIP00000022753	ENSONIP00000058360	Leucine rich repeat containing G protein-coupled receptor 5.	Uncharacterized protein.	0.960
LGR5	Rnf43	ENSONIP00000022753	ENSONIP00000051519	Leucine rich repeat containing G protein-coupled receptor 5.	E3 ubiquitin-protein ligase RNF43.	0.852
LGR5	Rspo1	ENSONIP00000022753	ENSONIP00000020523	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 1.	0.983
LGR5	Rspo3	ENSONIP00000022753	ENSONIP00000009097	Leucine rich repeat containing G protein-coupled receptor 5.	R-spondin 3.	0.979