43 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100706013	Inositol polyphosphate phosphatase-like 1b. (1219 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (310 aa)
	gab2	GRB2-associated binding protein 2. (654 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
	I3JPD5_ORENI	Fibronectin type-III domain-containing protein. (341 aa)
	LOC100700918	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
	LOC100692645	Uncharacterized protein. (863 aa)
	LOC100696389	Uncharacterized protein. (320 aa)
	LOC100693657	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (735 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	LOC100705099	CRK proto-oncogene, adaptor protein. (315 aa)
	syk	Tyrosine-protein kinase. (615 aa)
	LOC100699525	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
	LOC100704264	Tyrosine-protein kinase. (1161 aa)
	I3K4E0_ORENI	Uncharacterized protein. (469 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	blk	Tyrosine-protein kinase. (523 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC100707861	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	LOC100708129	Tyrosine-protein kinase. (556 aa)
	LOC100710044	Tyrosine-protein kinase. (1160 aa)
	jak1	Tyrosine-protein kinase. (1183 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	I3KQM2_ORENI	Phosphoinositide-3-kinase, regulatory subunit 3a (gamma). (521 aa)
	LOC100690473	Phosphatidylinositol 3-kinase regulatory subunit gamma b. (698 aa)
	LOC100704479	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1072 aa)
	SHC4	SHC adaptor protein 4. (349 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1200 aa)
	I3JG35_ORENI	Cbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
	YES1	Tyrosine-protein kinase. (555 aa)
	Pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1085 aa)
	LOC100710015	Uncharacterized protein. (718 aa)
	grb2	Growth factor receptor-bound protein 2b. (222 aa)
	hck	Tyrosine-protein kinase. (555 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (616 aa)
	ptpn6	Protein tyrosine phosphatase non-receptor type 6. (590 aa)
	fyn	Tyrosine-protein kinase. (538 aa)
	pik3r1	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
	LOC100692564	Tyrosine-protein kinase. (1136 aa)
	LOC102079789	Fibronectin type-III domain-containing protein. (547 aa)
	LOC100707437	Uncharacterized protein. (714 aa)
	LOC100712315	Uncharacterized protein. (933 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	I3JG35_ORENI	ENSONIP00000047919	ENSONIP00000059356	Ubiquitin B.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100692645	ENSONIP00000047919	ENSONIP00000011884	Ubiquitin B.	Uncharacterized protein.	0.768
ENSONIP00000047919	LOC100699525	ENSONIP00000047919	ENSONIP00000014371	Ubiquitin B.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100700918	ENSONIP00000047919	ENSONIP00000011686	Ubiquitin B.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.445
ENSONIP00000047919	LOC100708129	ENSONIP00000047919	ENSONIP00000027542	Ubiquitin B.	Tyrosine-protein kinase.	0.478
ENSONIP00000047919	YES1	ENSONIP00000047919	ENSONIP00000059411	Ubiquitin B.	Tyrosine-protein kinase.	0.478
ENSONIP00000047919	blk	ENSONIP00000047919	ENSONIP00000019292	Ubiquitin B.	Tyrosine-protein kinase.	0.478
ENSONIP00000047919	fyn	ENSONIP00000047919	ENSONIP00000072217	Ubiquitin B.	Tyrosine-protein kinase.	0.466
ENSONIP00000047919	grb2	ENSONIP00000047919	ENSONIP00000064237	Ubiquitin B.	Growth factor receptor-bound protein 2b.	0.680
ENSONIP00000047919	hck	ENSONIP00000047919	ENSONIP00000064640	Ubiquitin B.	Tyrosine-protein kinase.	0.478
ENSONIP00000047919	ptpn11	ENSONIP00000047919	ENSONIP00000071113	Ubiquitin B.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.445
ENSONIP00000047919	ptpn6	ENSONIP00000047919	ENSONIP00000071711	Ubiquitin B.	Protein tyrosine phosphatase non-receptor type 6.	0.445
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	syk	ENSONIP00000047919	ENSONIP00000014124	Ubiquitin B.	Tyrosine-protein kinase.	0.599
ENSONIP00000047919	uba52	ENSONIP00000047919	ENSONIP00000016035	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997
I3JG35_ORENI	ENSONIP00000047919	ENSONIP00000059356	ENSONIP00000047919	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Ubiquitin B.	0.768
I3JG35_ORENI	I3K4E0_ORENI	ENSONIP00000059356	ENSONIP00000015985	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Uncharacterized protein.	0.611
I3JG35_ORENI	I3KQM2_ORENI	ENSONIP00000059356	ENSONIP00000055517	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Phosphoinositide-3-kinase, regulatory subunit 3a (gamma).	0.611
I3JG35_ORENI	LOC100690473	ENSONIP00000059356	ENSONIP00000056948	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Phosphatidylinositol 3-kinase regulatory subunit gamma b.	0.625
I3JG35_ORENI	LOC100692564	ENSONIP00000059356	ENSONIP00000076598	Cbl proto-oncogene, E3 ubiquitin protein ligase.	Tyrosine-protein kinase.	0.424