STRINGSTRING
fgf6 fgf6 fndc3a fndc3a mapk1 mapk1 LOC100697722 LOC100697722 ENSONIP00000073729 ENSONIP00000073729 fgf1 fgf1 LOC100708453 LOC100708453 LOC100704516 LOC100704516 grb2 grb2 LOC100692677 LOC100692677 LOC100711270 LOC100711270 I3JG35_ORENI I3JG35_ORENI LOC100694765 LOC100694765 LOC100699012 LOC100699012 fgf17 fgf17 ENSONIP00000047919 ENSONIP00000047919 fgf19 fgf19 fgf4 fgf4 LOC100693787 LOC100693787 fgf16 fgf16 fgf20b fgf20b LOC100707945 LOC100707945 ppp2ca ppp2ca fgf20a fgf20a rps27a rps27a LOC100691488 LOC100691488 LOC100705713 LOC100705713 uba52 uba52 LOC100699525 LOC100699525 mknk2 mknk2 LOC100692645 LOC100692645 SRC SRC ppp2r1b ppp2r1b LOC100710281 LOC100710281 fgf2 fgf2 fgf23 fgf23
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
fndc3aFibronectin type III domain containing 3A. (1239 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC100697722Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
ENSONIP00000073729Fibroblast growth factor receptor substrate 2b. (500 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
LOC100708453Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC100704516Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
grb2Growth factor receptor-bound protein 2b. (222 aa)
LOC100692677Tyrosine-protein kinase. (593 aa)
LOC100711270MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (466 aa)
I3JG35_ORENICbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
LOC100694765Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC100699012Fibronectin type III domain containing 3Ba. (1174 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
fgf19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
LOC100693787Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
fgf16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf20bFibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC100707945Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC100691488Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC100705713Serine/threonine-protein phosphatase. (311 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
LOC100699525Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
LOC100692645Uncharacterized protein. (863 aa)
SRCTyrosine-protein kinase. (550 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (676 aa)
LOC100710281Serine/threonine-protein phosphatase. (309 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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