STRINGSTRING
ppp2ca ppp2ca fgf20a fgf20a rps27a rps27a fgf23 fgf23 I3JJI6_ORENI I3JJI6_ORENI I3J6X6_ORENI I3J6X6_ORENI LOC100696746 LOC100696746 SPRED2 SPRED2 flrt3 flrt3 LOC100696108 LOC100696108 LOC100694765 LOC100694765 LOC100704479 LOC100704479 SHC4 SHC4 I3JG35_ORENI I3JG35_ORENI LOC100711270 LOC100711270 LOC100692677 LOC100692677 grb2 grb2 LOC100703836 LOC100703836 LOC100698788 LOC100698788 LOC100704516 LOC100704516 LOC100708453 LOC100708453 fgf1 fgf1 ENSONIP00000073729 ENSONIP00000073729 ENSONIP00000074581 ENSONIP00000074581 LOC100697722 LOC100697722 mapk1 mapk1 fndc3a fndc3a ENSONIP00000078138 ENSONIP00000078138 ANOS1 ANOS1 kras kras LOC100691488 LOC100691488 LOC100705713 LOC100705713 uba52 uba52 I3K441_ORENI I3K441_ORENI LOC100699525 LOC100699525 PIK3CA PIK3CA mknk2 mknk2 LOC100698047 LOC100698047 I3JUL5_ORENI I3JUL5_ORENI LOC100692645 LOC100692645 SRC SRC LOC100694452 LOC100694452 LOC100707394 LOC100707394 shc1 shc1 ppp2r1b ppp2r1b fgfrl1 fgfrl1 ENSONIP00000036502 ENSONIP00000036502 spred1 spred1 fgf2 fgf2 LOC100710281 LOC100710281 fgf22 fgf22 FGFR1 FGFR1 I3KYM4_ORENI I3KYM4_ORENI LOC100699012 LOC100699012 CSDE1 CSDE1 LOC100696824 LOC100696824 I3KNU7_ORENI I3KNU7_ORENI fgf17 fgf17 ENSONIP00000047919 ENSONIP00000047919 hras hras fgf6 fgf6 fgf5 fgf5 fgf10 fgf10 ENSONIP00000039289 ENSONIP00000039289 fgf4 fgf4 LOC100707861 LOC100707861 LOC100693787 LOC100693787 fgf20b fgf20b LOC100707945 LOC100707945 plcg1 plcg1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ppp2caSerine/threonine-protein phosphatase. (309 aa)
fgf20aFibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
rps27aRibosomal protein S27a. (156 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)
I3JJI6_ORENIDDE_Tnp_1_7 domain-containing protein. (510 aa)
I3J6X6_ORENIFibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
LOC100696746Anosmin 1a. (654 aa)
SPRED2Sprouty related EVH1 domain containing 2. (476 aa)
flrt3Fibronectin leucine rich transmembrane 3. (650 aa)
LOC100696108Fibronectin leucine rich transmembrane protein 1. (684 aa)
LOC100694765Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC100704479Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1072 aa)
SHC4SHC adaptor protein 4. (349 aa)
I3JG35_ORENICbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
LOC100711270MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (466 aa)
LOC100692677Tyrosine-protein kinase. (593 aa)
grb2Growth factor receptor-bound protein 2b. (222 aa)
LOC100703836Zgc:55558. (250 aa)
LOC100698788Fibroblast growth factor receptor substrate 3. (613 aa)
LOC100704516Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
LOC100708453Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
ENSONIP00000073729Fibroblast growth factor receptor substrate 2b. (500 aa)
ENSONIP00000074581PiggyBac transposable element-derived protein 4. (431 aa)
LOC100697722Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
fndc3aFibronectin type III domain containing 3A. (1239 aa)
ENSONIP00000078138PiggyBac transposable element-derived protein 4. (371 aa)
ANOS1Anosmin 1. (673 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
LOC100691488Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC100705713Serine/threonine-protein phosphatase. (311 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
I3K441_ORENIUncharacterized protein. (268 aa)
LOC100699525Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
mknk2MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
LOC100698047Anosmin 1b. (724 aa)
I3JUL5_ORENIGRB2-associated binding protein 1. (777 aa)
LOC100692645Uncharacterized protein. (863 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC100694452Sprouty related EVH1 domain containing 2a. (492 aa)
LOC100707394PH domain-containing protein. (781 aa)
shc1SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
ppp2r1bProtein phosphatase 2, regulatory subunit A, beta b. (676 aa)
fgfrl1Fibroblast growth factor receptor like 1a. (494 aa)
ENSONIP00000036502LOW QUALITY PROTEIN: leucine-rich repeat transmembrane protein FLRT1. (657 aa)
spred1Sprouty related EVH1 domain containing 1. (451 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC100710281Serine/threonine-protein phosphatase. (309 aa)
fgf22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
FGFR1Fibroblast growth factor receptor. (862 aa)
I3KYM4_ORENIFibronectin leucine rich transmembrane protein 2. (608 aa)
LOC100699012Fibronectin type III domain containing 3Ba. (1174 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (873 aa)
LOC100696824Uncharacterized protein. (504 aa)
I3KNU7_ORENIFibroblast growth factor; Belongs to the heparin-binding growth factors family. (262 aa)
fgf17Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
fgf6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
fgf5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
fgf10Fibroblast growth factor 10. (251 aa)
ENSONIP00000039289annotation not available (471 aa)
fgf4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
LOC100707861Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
LOC100693787Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
fgf20bFibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
LOC100707945Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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