54 items (Oreochromis niloticus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100692645	Uncharacterized protein. (863 aa)
	ENSONIP00000078138	PiggyBac transposable element-derived protein 4. (371 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1239 aa)
	GALNT3	Polypeptide N-acetylgalactosaminyltransferase. (624 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC100697722	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
	ENSONIP00000074581	PiggyBac transposable element-derived protein 4. (431 aa)
	ENSONIP00000073729	Fibroblast growth factor receptor substrate 2b. (500 aa)
	fgf1	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (182 aa)
	LOC100704516	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family. (210 aa)
	LOC100698788	Fibroblast growth factor receptor substrate 3. (613 aa)
	LOC100703836	Zgc:55558. (250 aa)
	grb2	Growth factor receptor-bound protein 2b. (222 aa)
	LOC100692677	Tyrosine-protein kinase. (593 aa)
	LOC100711270	MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (466 aa)
	I3JG35_ORENI	Cbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
	SHC4	SHC adaptor protein 4. (349 aa)
	LOC100704479	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1072 aa)
	LOC100694765	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	ENSONIP00000053507	annotation not available (305 aa)
	LOC100699012	Fibronectin type III domain containing 3Ba. (1174 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (873 aa)
	fgf17	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	fgf5	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
	ENSONIP00000039289	annotation not available (471 aa)
	I3JJI6_ORENI	DDE_Tnp_1_7 domain-containing protein. (510 aa)
	LOC100705948	Polypeptide N-acetylgalactosaminyltransferase. (620 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
	LOC100707861	Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
	LOC100693787	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (154 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	fgf20b	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC100707945	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (201 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
	ppp2ca	Serine/threonine-protein phosphatase. (309 aa)
	fgf20a	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (224 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC100691488	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	LOC100705713	Serine/threonine-protein phosphatase. (311 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC100699525	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
	mknk2	MAPK interacting serine/threonine kinase 2b; Belongs to the protein kinase superfamily. (475 aa)
	I3JUL5_ORENI	GRB2-associated binding protein 1. (777 aa)
	SRC	Tyrosine-protein kinase. (550 aa)
	LOC100707394	PH domain-containing protein. (781 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
	ppp2r1b	Protein phosphatase 2, regulatory subunit A, beta b. (676 aa)
	LOC100710281	Serine/threonine-protein phosphatase. (309 aa)
	fgf2	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
	fgf23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSONIP00000047919	ENSONIP00000052211	ENSONIP00000047919	Cold shock domain containing E1, RNA-binding.	Ubiquitin B.	0.488
CSDE1	ENSONIP00000073729	ENSONIP00000052211	ENSONIP00000073729	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 2b.	0.430
CSDE1	LOC100691488	ENSONIP00000052211	ENSONIP00000016574	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.454
CSDE1	LOC100692677	ENSONIP00000052211	ENSONIP00000059722	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.404
CSDE1	LOC100693787	ENSONIP00000052211	ENSONIP00000022577	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.415
CSDE1	LOC100694765	ENSONIP00000052211	ENSONIP00000055316	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.469
CSDE1	LOC100697722	ENSONIP00000052211	ENSONIP00000075987	Cold shock domain containing E1, RNA-binding.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.437
CSDE1	LOC100698788	ENSONIP00000052211	ENSONIP00000066740	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor receptor substrate 3.	0.430
CSDE1	LOC100704479	ENSONIP00000052211	ENSONIP00000058182	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.508
CSDE1	LOC100704516	ENSONIP00000052211	ENSONIP00000067394	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 18a; Belongs to the heparin-binding growth factors family.	0.469
CSDE1	LOC100707861	ENSONIP00000052211	ENSONIP00000022585	Cold shock domain containing E1, RNA-binding.	Zgc:158659; Belongs to the PI3/PI4-kinase family.	0.508
CSDE1	LOC100707945	ENSONIP00000052211	ENSONIP00000022026	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.435
CSDE1	PIK3CA	ENSONIP00000052211	ENSONIP00000013444	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.508
CSDE1	SHC4	ENSONIP00000052211	ENSONIP00000058468	Cold shock domain containing E1, RNA-binding.	SHC adaptor protein 4.	0.416
CSDE1	SRC	ENSONIP00000052211	ENSONIP00000008685	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein kinase.	0.404
CSDE1	fgf1	ENSONIP00000052211	ENSONIP00000072944	Cold shock domain containing E1, RNA-binding.	Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...]	0.415
CSDE1	fgf17	ENSONIP00000052211	ENSONIP00000048092	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.451
CSDE1	fgf23	ENSONIP00000052211	ENSONIP00000000020	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.	0.439
CSDE1	fgf4	ENSONIP00000052211	ENSONIP00000022794	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.435
CSDE1	fgf5	ENSONIP00000052211	ENSONIP00000043638	Cold shock domain containing E1, RNA-binding.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.441