57 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	usp45	Ubiquitin carboxyl-terminal hydrolase. (823 aa)
	LOC100695822	Centrin 4. (171 aa)
	xpc	Xeroderma pigmentosum, complementation group C. (930 aa)
	ercc5	Excision repair cross-complementation group 5. (1111 aa)
	ercc3	Excision repair cross-complementation group 3. (802 aa)
	ercc1	Excision repair cross-complementation group 1. (352 aa)
	gtf2h4	General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (479 aa)
	rnf111	Ring finger protein 111. (1006 aa)
	rad23a	RAD23 homolog A, nucleotide excision repair protein a. (365 aa)
	ercc2	Excision repair cross-complementation group 2. (760 aa)
	rbx1	Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
	vwa5b2	Von Willebrand factor A domain containing 5B2. (1401 aa)
	LOC100696048	General transcription factor IIH subunit. (392 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	gtf2h3	General transcription factor IIH, polypeptide 3. (303 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	RAD23B	RAD23 homolog B, nucleotide excision repair protein. (369 aa)
	Parp2	Poly [ADP-ribose] polymerase. (619 aa)
	pias1	Protein inhibitor of activated STAT, 1b. (657 aa)
	Ddb2	Damage-specific DNA binding protein 2. (443 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	rpa2	Replication protein A2. (278 aa)
	xpa	Xeroderma pigmentosum, complementation group A. (271 aa)
	kctd2	Potassium channel tetramerization domain containing 2. (273 aa)
	parp3	Poly [ADP-ribose] polymerase. (539 aa)
	Bivm	Basic, immunoglobulin-like variable motif containing. (518 aa)
	meiob	Methionine sulfoxide reductase B1b. (464 aa)
	mnat1	CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (311 aa)
	RPA1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (665 aa)
	LOC100712348	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (254 aa)
	Cul4b	Cullin-4B. (869 aa)
	ube2v2	Ubiquitin-conjugating enzyme E2 variant 2. (148 aa)
	I3JLC5_ORENI	Uncharacterized protein. (506 aa)
	LOC109202395	Small ubiquitin-related modifier 2. (145 aa)
	LOC100690637	Small ubiquitin-related modifier. (94 aa)
	wdr76	WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (551 aa)
	ccnh	Cyclin H; Belongs to the cyclin family. (325 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	cetn3	Centrin 3. (181 aa)
	ercc4	Excision repair cross-complementation group 4. (909 aa)
	cdk7	Cyclin-dependent kinase 7; Belongs to the protein kinase superfamily. (347 aa)
	LOC100699741	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
	gtf2h1	General transcription factor IIH, polypeptide 1. (556 aa)
	ENSONIP00000061996	annotation not available (157 aa)
	sumo2	Small ubiquitin-related modifier. (95 aa)
	ENSONIP00000064374	Small ubiquitin-related modifier 2. (90 aa)
	gtf2h5	General transcription factor IIH, polypeptide 5. (71 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	LOC100692112	Protein inhibitor of activated STAT, 1a. (722 aa)
	LOC100709166	Small ubiquitin-related modifier. (94 aa)
	rpa1	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
	ddb1	Damage-specific DNA binding protein 1. (1140 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)
	parp1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1023 aa)
	cul4a	Cullin 4A; Belongs to the cullin family. (819 aa)
	rpa3	Replication protein A3. (122 aa)
	Chd1l	Chromodomain helicase DNA binding protein 1-like. (1013 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Bivm	Chd1l	ENSONIP00000024339	ENSONIP00000081597	Basic, immunoglobulin-like variable motif containing.	Chromodomain helicase DNA binding protein 1-like.	0.702
Bivm	Cul4b	ENSONIP00000024339	ENSONIP00000030664	Basic, immunoglobulin-like variable motif containing.	Cullin-4B.	0.607
Bivm	Ddb2	ENSONIP00000024339	ENSONIP00000019498	Basic, immunoglobulin-like variable motif containing.	Damage-specific DNA binding protein 2.	0.706
Bivm	ENSONIP00000047919	ENSONIP00000024339	ENSONIP00000047919	Basic, immunoglobulin-like variable motif containing.	Ubiquitin B.	0.589
Bivm	ENSONIP00000064374	ENSONIP00000024339	ENSONIP00000064374	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier 2.	0.496
Bivm	I3JLC5_ORENI	ENSONIP00000024339	ENSONIP00000032184	Basic, immunoglobulin-like variable motif containing.	Uncharacterized protein.	0.595
Bivm	LOC100690637	ENSONIP00000024339	ENSONIP00000037316	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier.	0.496
Bivm	LOC100695822	ENSONIP00000024339	ENSONIP00000001776	Basic, immunoglobulin-like variable motif containing.	Centrin 4.	0.544
Bivm	LOC100696048	ENSONIP00000024339	ENSONIP00000013134	Basic, immunoglobulin-like variable motif containing.	General transcription factor IIH subunit.	0.883
Bivm	LOC100699741	ENSONIP00000024339	ENSONIP00000060489	Basic, immunoglobulin-like variable motif containing.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.512
Bivm	LOC100709166	ENSONIP00000024339	ENSONIP00000068525	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier.	0.496
Bivm	LOC100712348	ENSONIP00000024339	ENSONIP00000030218	Basic, immunoglobulin-like variable motif containing.	Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family.	0.512
Bivm	LOC109202395	ENSONIP00000024339	ENSONIP00000034808	Basic, immunoglobulin-like variable motif containing.	Small ubiquitin-related modifier 2.	0.496
Bivm	Parp2	ENSONIP00000024339	ENSONIP00000019125	Basic, immunoglobulin-like variable motif containing.	Poly [ADP-ribose] polymerase.	0.595
Bivm	RAD23B	ENSONIP00000024339	ENSONIP00000018833	Basic, immunoglobulin-like variable motif containing.	RAD23 homolog B, nucleotide excision repair protein.	0.595
Bivm	RPA1	ENSONIP00000024339	ENSONIP00000027967	Basic, immunoglobulin-like variable motif containing.	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	0.689
Bivm	ccnh	ENSONIP00000024339	ENSONIP00000039660	Basic, immunoglobulin-like variable motif containing.	Cyclin H; Belongs to the cyclin family.	0.563
Bivm	cetn3	ENSONIP00000024339	ENSONIP00000052247	Basic, immunoglobulin-like variable motif containing.	Centrin 3.	0.476
Bivm	cul4a	ENSONIP00000024339	ENSONIP00000076782	Basic, immunoglobulin-like variable motif containing.	Cullin 4A; Belongs to the cullin family.	0.607
Bivm	ddb1	ENSONIP00000024339	ENSONIP00000071715	Basic, immunoglobulin-like variable motif containing.	Damage-specific DNA binding protein 1.	0.765