24 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100704272	SH3-domain GRB2-like 1b. (351 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	hgf	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (711 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC100698524	Uncharacterized protein. (348 aa)
	LOC100699525	Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
	LOC100692645	Uncharacterized protein. (863 aa)
	LOC100702382	Tyrosine-protein phosphatase non-receptor type. (413 aa)
	sh3kbp1	SH3-domain kinase binding protein 1. (733 aa)
	cd2ap	CD2-associated protein. (646 aa)
	LOC100711916	Tyrosine-protein phosphatase non-receptor type. (403 aa)
	Sh3d21	SH3 domain containing 21. (504 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1423 aa)
	LOC100692909	SH3 domain containing GRB2 like 2a, endophilin A1. (363 aa)
	LOC100692766	SH3-domain GRB2-like 3a. (384 aa)
	LOC100708054	Epidermal growth factor receptor substrate 15 isoform X2. (1103 aa)
	grb2	Growth factor receptor-bound protein 2b. (222 aa)
	lrig1	Leucine-rich repeats and immunoglobulin-like domains 1. (1046 aa)
	I3JG35_ORENI	Cbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
	stam2	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2. (517 aa)
	hgs	Hepatocyte growth factor-regulated tyrosine kinase substrate. (786 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	stam	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1. (522 aa)
	LOC100694996	Tyrosine-protein phosphatase non-receptor type. (424 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000047919	I3JG35_ORENI	ENSONIP00000047919	ENSONIP00000059356	Ubiquitin B.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100692645	ENSONIP00000047919	ENSONIP00000011884	Ubiquitin B.	Uncharacterized protein.	0.768
ENSONIP00000047919	LOC100692766	ENSONIP00000047919	ENSONIP00000071242	Ubiquitin B.	SH3-domain GRB2-like 3a.	0.559
ENSONIP00000047919	LOC100692909	ENSONIP00000047919	ENSONIP00000074477	Ubiquitin B.	SH3 domain containing GRB2 like 2a, endophilin A1.	0.559
ENSONIP00000047919	LOC100698524	ENSONIP00000047919	ENSONIP00000014622	Ubiquitin B.	Uncharacterized protein.	0.559
ENSONIP00000047919	LOC100699525	ENSONIP00000047919	ENSONIP00000014371	Ubiquitin B.	Cbl proto-oncogene C, E3 ubiquitin protein ligase.	0.768
ENSONIP00000047919	LOC100704272	ENSONIP00000047919	ENSONIP00000027062	Ubiquitin B.	SH3-domain GRB2-like 1b.	0.559
ENSONIP00000047919	LOC100708054	ENSONIP00000047919	ENSONIP00000067563	Ubiquitin B.	Epidermal growth factor receptor substrate 15 isoform X2.	0.909
ENSONIP00000047919	Sh3d21	ENSONIP00000047919	ENSONIP00000080950	Ubiquitin B.	SH3 domain containing 21.	0.795
ENSONIP00000047919	cd2ap	ENSONIP00000047919	ENSONIP00000008119	Ubiquitin B.	CD2-associated protein.	0.795
ENSONIP00000047919	grb2	ENSONIP00000047919	ENSONIP00000064237	Ubiquitin B.	Growth factor receptor-bound protein 2b.	0.680
ENSONIP00000047919	hgf	ENSONIP00000047919	ENSONIP00000018794	Ubiquitin B.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.502
ENSONIP00000047919	hgs	ENSONIP00000047919	ENSONIP00000055956	Ubiquitin B.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.994
ENSONIP00000047919	lrig1	ENSONIP00000047919	ENSONIP00000061656	Ubiquitin B.	Leucine-rich repeats and immunoglobulin-like domains 1.	0.510
ENSONIP00000047919	met	ENSONIP00000047919	ENSONIP00000080477	Ubiquitin B.	MET proto-oncogene, receptor tyrosine kinase.	0.551
ENSONIP00000047919	rps27a	ENSONIP00000047919	ENSONIP00000020250	Ubiquitin B.	Ribosomal protein S27a.	0.994
ENSONIP00000047919	sh3kbp1	ENSONIP00000047919	ENSONIP00000008180	Ubiquitin B.	SH3-domain kinase binding protein 1.	0.795
ENSONIP00000047919	stam	ENSONIP00000047919	ENSONIP00000031308	Ubiquitin B.	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.	0.947
ENSONIP00000047919	stam2	ENSONIP00000047919	ENSONIP00000058605	Ubiquitin B.	Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.	0.948
ENSONIP00000047919	uba52	ENSONIP00000047919	ENSONIP00000016035	Ubiquitin B.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.997