STRINGSTRING
Ube2c Ube2c psme4 psme4 LOC100694127 LOC100694127 cdc16 cdc16 psma6 psma6 psmc1 psmc1 psmc2 psmc2 psmd6 psmd6 cdk2 cdk2 bicral bicral LOC100698550 LOC100698550 psmd13 psmd13 I3KG36_ORENI I3KG36_ORENI LOC100703712 LOC100703712 psmb7 psmb7 psmf1 psmf1 orc5 orc5 I3IXS1_ORENI I3IXS1_ORENI ccna2 ccna2 mcm8 mcm8 LOC100692568 LOC100692568 LOC100707077 LOC100707077 anapc4 anapc4 psmb3 psmb3 psmd14 psmd14 Ccne1 Ccne1 orc3 orc3 Psmb4 Psmb4 bicra bicra Psmd8 Psmd8 PSMA4 PSMA4 psmd12 psmd12 psme2 psme2 psma2 psma2 psmd5 psmd5 orc1 orc1 psme1 psme1 mcm5 mcm5 rbx1 rbx1 ENSONIP00000010727 ENSONIP00000010727 LOC100705137 LOC100705137 cdc27 cdc27 Anapc2 Anapc2 mcm4 mcm4 psma8 psma8 FZR1 FZR1 anapc5 anapc5 skp2 skp2 LOC100705995 LOC100705995 anapc10 anapc10 ccna1 ccna1 uba52 uba52 Ube2s Ube2s cdt1 cdt1 cdc6 cdc6 psmd9 psmd9 psmb2 psmb2 kxd1 kxd1 psmd7 psmd7 I3KF05_ORENI I3KF05_ORENI mcm6 mcm6 anapc7 anapc7 rps27a rps27a LOC100701743 LOC100701743 anapc15 anapc15 psmc3 psmc3 skp1 skp1 LOC100706559 LOC100706559 psme3 psme3 fam89a fam89a I3KQQ3_ORENI I3KQQ3_ORENI psma5 psma5 I3KUR8_ORENI I3KUR8_ORENI LOC100696839 LOC100696839 LOC100697106 LOC100697106 LOC100697564 LOC100697564 psmb8 psmb8 psmc4 psmc4 LOC100697459 LOC100697459 mcm9 mcm9 anapc16 anapc16 LOC100691978 LOC100691978 psmd1 psmd1 LOC102075526 LOC102075526 LOC100710977 LOC100710977 mcm2 mcm2 LOC100705406 LOC100705406 Psmd10 Psmd10 tm7sf3 tm7sf3 cul1 cul1 psmb1 psmb1 psmd3 psmd3 ENSONIP00000047919 ENSONIP00000047919 anapc11 anapc11 psmc6 psmc6 psma1 psma1 MCM7 MCM7 LOC102080582 LOC102080582 Orc4 Orc4 psmc5 psmc5 mcm3 mcm3 ENSONIP00000058178 ENSONIP00000058178 psma3 psma3 ENSONIP00000064494 ENSONIP00000064494 LOC100694980 LOC100694980 cdc23 cdc23 cdc26 cdc26
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
psme4Proteasome activator subunit 4a. (1847 aa)
LOC100694127WD_REPEATS_REGION domain-containing protein. (489 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (621 aa)
psma6Proteasome 20S subunit alpha 6. (254 aa)
psmc1Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family. (474 aa)
psmc2Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (487 aa)
psmd6Proteasome 26S subunit, non-ATPase 6. (407 aa)
cdk2Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (313 aa)
bicralBRD4 interacting chromatin remodeling complex associated protein like. (800 aa)
LOC100698550Proteasome subunit beta. (390 aa)
psmd13Proteasome 26S subunit, non-ATPase 13. (379 aa)
I3KG36_ORENIProteasome activator subunit 4b. (1840 aa)
LOC100703712PCI domain-containing protein. (445 aa)
psmb7Proteasome subunit beta. (326 aa)
psmf1Proteasome inhibitor subunit 1. (326 aa)
orc5Origin recognition complex, subunit 5. (445 aa)
I3IXS1_ORENIAnaphase promoting complex subunit 1. (1773 aa)
ccna2Cyclin A2; Belongs to the cyclin family. (434 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (876 aa)
LOC100692568Cyclin E2; Belongs to the cyclin family. (397 aa)
LOC100707077Geminin DNA replication inhibitor. (211 aa)
anapc4Anaphase promoting complex subunit 4. (808 aa)
psmb3Proteasome subunit beta. (205 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (333 aa)
Ccne1Cyclin E1; Belongs to the cyclin family. (296 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
Psmb4Proteasome subunit beta; Belongs to the peptidase T1B family. (259 aa)
bicraBRD4 interacting chromatin remodeling complex associated protein. (1859 aa)
Psmd8Proteasome 26S subunit, non-ATPase 8. (258 aa)
PSMA4Proteasome subunit alpha type. (248 aa)
psmd12Proteasome 26S subunit, non-ATPase 12. (456 aa)
psme2Proteasome activator subunit 2. (245 aa)
psma2Proteasome subunit alpha type. (234 aa)
psmd5Proteasome 26S subunit, non-ATPase 5. (524 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (901 aa)
psme1Proteasome activator subunit 1. (249 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
ENSONIP00000010727Geminin. (215 aa)
LOC100705137Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
cdc27Cell division cycle 27. (803 aa)
Anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (797 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
psma8Proteasome subunit alpha type. (270 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (496 aa)
anapc5Anaphase promoting complex subunit 5. (771 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (419 aa)
LOC100705995Proteasome subunit beta. (289 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
ccna1Cyclin A1; Belongs to the cyclin family. (396 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
Ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (267 aa)
cdt1Chromatin licensing and DNA replication factor 1. (556 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (604 aa)
psmd9Proteasome 26S subunit, non-ATPase 9. (212 aa)
psmb2Proteasome subunit beta. (204 aa)
kxd1KxDL motif containing 1. (184 aa)
psmd7Proteasome 26S subunit, non-ATPase 7. (337 aa)
I3KF05_ORENIUncharacterized protein. (510 aa)
mcm6DNA helicase; Belongs to the MCM family. (828 aa)
anapc7Anaphase promoting complex subunit 7. (580 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC100701743Proteasome subunit alpha type. (246 aa)
anapc15Anaphase promoting complex subunit 15. (122 aa)
psmc3Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (428 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC100706559Proteasome 26S subunit, non-ATPase 11b. (424 aa)
psme3Proteasome activator subunit 3. (256 aa)
fam89aFamily with sequence similarity 89 member A. (180 aa)
I3KQQ3_ORENIFizzy/cell division cycle 20 related 1b. (487 aa)
psma5Proteasome subunit alpha type. (241 aa)
I3KUR8_ORENIProteasome 26S subunit, non-ATPase 4a. (393 aa)
LOC100696839Proteasome subunit beta. (217 aa)
LOC100697106Proteasome subunit beta 12. (217 aa)
LOC100697564Proteasome subunit beta. (275 aa)
psmb8Proteasome subunit beta. (275 aa)
psmc4Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (417 aa)
LOC100697459Ubiquitin-conjugating enzyme E2 E2. (206 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1201 aa)
anapc16Anaphase promoting complex subunit 16. (108 aa)
LOC100691978Proteasome subunit alpha type. (256 aa)
psmd126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (961 aa)
LOC102075526Cyclin E2; Belongs to the cyclin family. (431 aa)
LOC100710977Proteasome subunit beta. (281 aa)
mcm2DNA helicase; Belongs to the MCM family. (899 aa)
LOC100705406UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
Psmd10Proteasome 26S subunit, non-ATPase 10. (228 aa)
tm7sf3Transmembrane 7 superfamily member 3. (565 aa)
cul1Cullin 1b; Belongs to the cullin family. (1038 aa)
psmb1Proteasome subunit beta. (263 aa)
psmd3Proteasome 26S subunit, non-ATPase 3. (575 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
psmc6Proteasome 26S subunit, ATPase 6; Belongs to the AAA ATPase family. (435 aa)
psma1Proteasome subunit alpha type. (263 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (743 aa)
LOC102080582Proteasome 26S subunit, non-ATPase 4b. (401 aa)
Orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (454 aa)
psmc5Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family. (421 aa)
mcm3DNA helicase; Belongs to the MCM family. (817 aa)
ENSONIP00000058178Proteasome subunit beta type-11-like. (305 aa)
psma3Proteasome subunit alpha type. (285 aa)
ENSONIP00000064494annotation not available (266 aa)
LOC100694980Proteasome subunit beta. (327 aa)
cdc23CDC23 (cell division cycle 23, yeast, homolog). (599 aa)
cdc26Cell division cycle 26 homolog. (97 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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