(57 nodes) Gluconeogenesis network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100534530	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (352 aa)
	LOC100696029	Triosephosphate isomerase. (248 aa)
	LOC100703097	Glutamic-oxaloacetic transaminase 1 like 1. (464 aa)
	SLC25A12	Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (696 aa)
	LOC100694503	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (419 aa)
	ENSONIP00000050201	Enolase 1b, (alpha). (471 aa)
	LOC100692382	Lecithin retinol acyltransferase b, tandem duplicate 1. (695 aa)
	slc37a2	Solute carrier family 37 member 2. (503 aa)
	g6pc3	Glucose-6-phosphatase 3. (339 aa)
	LOC100705311	Aspartate aminotransferase. (449 aa)
	LOC100699677	Enolase 3, (beta, muscle). (464 aa)
	LOC100711978	Malate dehydrogenase. (383 aa)
	PC	Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1209 aa)
	LOC100700247	Solute carrier family 25 member 12; Belongs to the mitochondrial carrier (TC 2.A.29) family. (689 aa)
	fam126b	Zgc:158316. (643 aa)
	LOC100704344	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (422 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
	pck2	Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (641 aa)
	mdh2	Malate dehydrogenase. (331 aa)
	ald	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
	LOC100692737	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	got1	Aspartate aminotransferase. (414 aa)
	g6pc	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
	I3KPD3_ORENI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
	pgk1	Phosphoglycerate kinase. (417 aa)
	slc37a3	MFS domain-containing protein. (502 aa)
	mycbpap	Mycbp associated protein. (745 aa)
	LOC100693267	Solute carrier family 25 member 10; Belongs to the mitochondrial carrier (TC 2.A.29) family. (290 aa)
	Iqch	IQ motif containing H. (866 aa)
	LOC100697273	Si:dkey-178e17.1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (320 aa)
	LOC100703707	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (709 aa)
	mdh1b	Malate dehydrogenase 1B, NAD (soluble). (465 aa)
	LOC100707951	Solute carrier family 37 member 4b. (451 aa)
	LOC100705870	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (339 aa)
	eno4	Enolase 4. (568 aa)
	G6PC2	Glucose-6-phosphatase catalytic subunit 2. (358 aa)
	slc37a4	Solute carrier family 37 member 4a. (429 aa)
	pck1	Phosphoenolpyruvate carboxykinase 1 (soluble). (672 aa)
	I3J820_ORENI	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (264 aa)
	PM20D2	Peptidase M20 domain-containing protein 2; Belongs to the peptidase M20A family. (423 aa)
	LOC100704840	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	I3J0V2_ORENI	Si:ch1073-100f3.2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (287 aa)
	GOT1	Aspartate aminotransferase. (410 aa)
	slc25a13	Solute carrier family 25 member 13; Belongs to the mitochondrial carrier (TC 2.A.29) family. (679 aa)
	LOC100696823	Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
	pgam1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	LOC100710339	Solute carrier family 25 (mitochondrial citrate transporter), member 1. (327 aa)
	LOC100703167	Solute carrier family 25 member 1a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (357 aa)
	tpi	Triosephosphate isomerase. (247 aa)
	eno1	Enolase 1a, (alpha). (451 aa)
	I3K606_ORENI	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (405 aa)
	LOC100696295	Enolase 2. (459 aa)
	slc37a1	Solute carrier family 37 member 1. (542 aa)
	ENO2	Enolase 2. (443 aa)
	slc25a11	Solute carrier family 25 member 11; Belongs to the mitochondrial carrier (TC 2.A.29) family. (301 aa)
	LOC100711262	Malate dehydrogenase, cytoplasmic isoform X2. (364 aa)
	gapdhs	Glyceraldehyde-3-phosphate dehydrogenase. (375 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENO2	ENSONIP00000050201	ENSONIP00000071624	ENSONIP00000050201	Enolase 2.	Enolase 1b, (alpha).	0.420
ENO2	I3J820_ORENI	ENSONIP00000071624	ENSONIP00000005010	Enolase 2.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.846
ENO2	I3K606_ORENI	ENSONIP00000071624	ENSONIP00000069672	Enolase 2.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.476
ENO2	I3KPD3_ORENI	ENSONIP00000071624	ENSONIP00000022978	Enolase 2.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.764
ENO2	LOC100692737	ENSONIP00000071624	ENSONIP00000023123	Enolase 2.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.712
ENO2	LOC100694503	ENSONIP00000071624	ENSONIP00000051034	Enolase 2.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.476
ENO2	LOC100696029	ENSONIP00000071624	ENSONIP00000080720	Enolase 2.	Triosephosphate isomerase.	0.936
ENO2	LOC100696823	ENSONIP00000071624	ENSONIP00000059789	Enolase 2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.722
ENO2	LOC100699677	ENSONIP00000071624	ENSONIP00000041483	Enolase 2.	Enolase 3, (beta, muscle).	0.425
ENO2	LOC100703707	ENSONIP00000071624	ENSONIP00000017869	Enolase 2.	Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family.	0.434
ENO2	LOC100704344	ENSONIP00000071624	ENSONIP00000033603	Enolase 2.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.476
ENO2	LOC100704840	ENSONIP00000071624	ENSONIP00000003599	Enolase 2.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.764
ENO2	LOC100705311	ENSONIP00000071624	ENSONIP00000041827	Enolase 2.	Aspartate aminotransferase.	0.525
ENO2	LOC100705870	ENSONIP00000071624	ENSONIP00000014009	Enolase 2.	Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family.	0.434
ENO2	LOC100711262	ENSONIP00000071624	ENSONIP00000076158	Enolase 2.	Malate dehydrogenase, cytoplasmic isoform X2.	0.435
ENO2	LOC100711978	ENSONIP00000071624	ENSONIP00000041331	Enolase 2.	Malate dehydrogenase.	0.435
ENO2	ald	ENSONIP00000071624	ENSONIP00000025311	Enolase 2.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.715
ENO2	eno1	ENSONIP00000071624	ENSONIP00000067914	Enolase 2.	Enolase 1a, (alpha).	0.430
ENO2	eno4	ENSONIP00000071624	ENSONIP00000011492	Enolase 2.	Enolase 4.	0.554
ENO2	gapdh	ENSONIP00000071624	ENSONIP00000033368	Enolase 2.	Glyceraldehyde-3-phosphate dehydrogenase.	0.722