(29 nodes) Branched-chain amino acid catabolism network (Oreochromis niloticus)

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proteins of unknown 3D structure

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Predicted Interactions

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Your Input:
	hibch	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (382 aa)
	LOC100706096	Aldedh domain-containing protein. (525 aa)
	LOC100691671	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	bckdha	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
	LOC100700576	Solute carrier family 25 member 44b; Belongs to the mitochondrial carrier (TC 2.A.29) family. (385 aa)
	Acad8	Acyl-CoA dehydrogenase family, member 8. (396 aa)
	bckdk	Protein-serine/threonine kinase. (482 aa)
	LOC100710671	Solute carrier family 25 member 44a; Belongs to the mitochondrial carrier (TC 2.A.29) family. (329 aa)
	ALDH6A1	Aldehyde dehydrogenase 6 family member A1. (519 aa)
	bckdhb	Branched chain keto acid dehydrogenase E1 subunit beta. (402 aa)
	dbt	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (486 aa)
	echdc2	Enoyl CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (277 aa)
	pcca	Propionyl-CoA carboxylase subunit alpha. (734 aa)
	ivd	Isovaleryl-CoA dehydrogenase. (417 aa)
	LOC100696541	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	I3JTP3_ORENI	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (412 aa)
	I3JQQ9_ORENI	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (375 aa)
	hsd17b10	Hydroxysteroid (17-beta) dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (260 aa)
	ENSONIP00000028816	annotation not available (260 aa)
	LOC100697026	Si:ch211-198n5.11. (619 aa)
	ppm1k	Protein phosphatase, Mg2+/Mn2+ dependent, 1K. (381 aa)
	LOC100695384	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family. (310 aa)
	LOC100700412	Si:ch211-149b19.3. (379 aa)
	LOC100700973	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (328 aa)
	dld	Dihydrolipoyl dehydrogenase. (508 aa)
	LOC100707807	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (367 aa)
	Echs1	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family. (401 aa)
	mccc1	Methylcrotonoyl-CoA carboxylase 1 (alpha). (715 aa)
	ECHDC1	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (311 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH6A1	ECHDC1	ENSONIP00000072252	ENSONIP00000009096	Aldehyde dehydrogenase 6 family member A1.	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.939
ALDH6A1	Echs1	ENSONIP00000072252	ENSONIP00000012057	Aldehyde dehydrogenase 6 family member A1.	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.510
ALDH6A1	LOC100691671	ENSONIP00000072252	ENSONIP00000003703	Aldehyde dehydrogenase 6 family member A1.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.981
ALDH6A1	LOC100695384	ENSONIP00000072252	ENSONIP00000018331	Aldehyde dehydrogenase 6 family member A1.	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.417
ALDH6A1	LOC100696541	ENSONIP00000072252	ENSONIP00000047536	Aldehyde dehydrogenase 6 family member A1.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.981
ALDH6A1	LOC100697026	ENSONIP00000072252	ENSONIP00000026991	Aldehyde dehydrogenase 6 family member A1.	Si:ch211-198n5.11.	0.444
ALDH6A1	LOC100706096	ENSONIP00000072252	ENSONIP00000001119	Aldehyde dehydrogenase 6 family member A1.	Aldedh domain-containing protein.	0.900
ALDH6A1	dbt	ENSONIP00000072252	ENSONIP00000063344	Aldehyde dehydrogenase 6 family member A1.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.492
ALDH6A1	hibch	ENSONIP00000072252	ENSONIP00000009031	Aldehyde dehydrogenase 6 family member A1.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.672
ALDH6A1	ivd	ENSONIP00000072252	ENSONIP00000050304	Aldehyde dehydrogenase 6 family member A1.	Isovaleryl-CoA dehydrogenase.	0.419
ALDH6A1	pcca	ENSONIP00000072252	ENSONIP00000051832	Aldehyde dehydrogenase 6 family member A1.	Propionyl-CoA carboxylase subunit alpha.	0.928
Acad8	ECHDC1	ENSONIP00000078659	ENSONIP00000009096	Acyl-CoA dehydrogenase family, member 8.	Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family.	0.622
Acad8	ENSONIP00000028816	ENSONIP00000078659	ENSONIP00000028816	Acyl-CoA dehydrogenase family, member 8.	annotation not available	0.513
Acad8	Echs1	ENSONIP00000078659	ENSONIP00000012057	Acyl-CoA dehydrogenase family, member 8.	Enoyl CoA hydratase, short chain, 1, mitochondrial; Belongs to the enoyl-CoA hydratase/isomerase family.	0.960
Acad8	I3JQQ9_ORENI	ENSONIP00000078659	ENSONIP00000032766	Acyl-CoA dehydrogenase family, member 8.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.513
Acad8	LOC100695384	ENSONIP00000078659	ENSONIP00000018331	Acyl-CoA dehydrogenase family, member 8.	Zgc:101569; Belongs to the enoyl-CoA hydratase/isomerase family.	0.622
Acad8	LOC100697026	ENSONIP00000078659	ENSONIP00000026991	Acyl-CoA dehydrogenase family, member 8.	Si:ch211-198n5.11.	0.584
Acad8	LOC100700973	ENSONIP00000078659	ENSONIP00000014128	Acyl-CoA dehydrogenase family, member 8.	AU RNA binding protein/enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.	0.513
Acad8	bckdha	ENSONIP00000078659	ENSONIP00000005081	Acyl-CoA dehydrogenase family, member 8.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.607
Acad8	bckdhb	ENSONIP00000078659	ENSONIP00000065756	Acyl-CoA dehydrogenase family, member 8.	Branched chain keto acid dehydrogenase E1 subunit beta.	0.463