STRINGSTRING
LOC100704174 LOC100704174 arhgef37 arhgef37 sqstm1 sqstm1 LOC100697238 LOC100697238 LOC102083126 LOC102083126 sos2 sos2 arhgef10l arhgef10l LOC100691526 LOC100691526 LOC100691708 LOC100691708 arhgef33 arhgef33 ARHGEF2 ARHGEF2 LOC100534578 LOC100534578 LOC100707598 LOC100707598 SPPL2A SPPL2A arhgef6 arhgef6 LOC100705827 LOC100705827 cyld cyld traf2 traf2 LOC100691403 LOC100691403 LOC100700935 LOC100700935 ulk1 ulk1 LOC102082089 LOC102082089 arhgef3 arhgef3 VAV3 VAV3 ARHGEF17 ARHGEF17 Tiam1 Tiam1 tradd tradd myd88 myd88 LOC100703008 LOC100703008 otulin otulin ENSONIP00000008001 ENSONIP00000008001 ngef ngef LOC100702305 LOC100702305 LOC100707250 LOC100707250 rbck1 rbck1 sestd1 sestd1 LOC100705259 LOC100705259 trio trio arhgef10 arhgef10 tiam2 tiam2 LOC109194206 LOC109194206 LOC100710405 LOC100710405 NET1 NET1 LOC100712109 LOC100712109 STUB1 STUB1 sharpin sharpin LOC100692869 LOC100692869 ripk1 ripk1 LOC100709969 LOC100709969 LOC100704015 LOC100704015 I3JW29_ORENI I3JW29_ORENI ulk2 ulk2 bag4 bag4 smpd3 smpd3 LOC100699294 LOC100699294 LOC100708442 LOC100708442 LOC100697530 LOC100697530 optn optn LOC100695566 LOC100695566 I3K3K8_ORENI I3K3K8_ORENI uba52 uba52 I3K4Y3_ORENI I3K4Y3_ORENI casp2 casp2 I3K566_ORENI I3K566_ORENI LOC100708196 LOC100708196 bad bad arhgef39 arhgef39 LOC100708611 LOC100708611 smpd2 smpd2 kxd1 kxd1 wdr31 wdr31 LOC100702139 LOC100702139 rps27a rps27a LOC100706660 LOC100706660 LOC100690570 LOC100690570 prdm4 prdm4 LOC100701610 LOC100701610 arhgef38 arhgef38 I3KLZ9_ORENI I3KLZ9_ORENI LOC100698148 LOC100698148 LOC100691909 LOC100691909 prkci prkci ENSONIP00000023653 ENSONIP00000023653 LOC100700172 LOC100700172 ikbke ikbke nfkbia nfkbia clip4 clip4 Sos1 Sos1 rtn1 rtn1 LOC100696018 LOC100696018 LOC100692989 LOC100692989 LOC106098144 LOC106098144 LOC100700742 LOC100700742 lingo2 lingo2 LOC100696124 LOC100696124 I3KZE4_ORENI I3KZE4_ORENI I3KZF2_ORENI I3KZF2_ORENI LOC100700983 LOC100700983 LOC100707993 LOC100707993 LOC100710620 LOC100710620 mib2 mib2 arhgef7 arhgef7 arhgef16 arhgef16 ARHGEF26 ARHGEF26 ENSONIP00000034589 ENSONIP00000034589 UBE2D3 UBE2D3 LOC100709217 LOC100709217 NCSTN NCSTN LOC100689713 LOC100689713 arhgef18 arhgef18 rack1 rack1 otud7b otud7b tbk1 tbk1 I3JS89_ORENI I3JS89_ORENI ENSONIP00000038243 ENSONIP00000038243 LOC100694779 LOC100694779 spata2 spata2 LOC100707781 LOC100707781 nsmaf nsmaf LOC100691074 LOC100691074 omg omg LOC100693654 LOC100693654 I3JRT5_ORENI I3JRT5_ORENI Bcl2l11 Bcl2l11 map3k20 map3k20 usp4 usp4 LOC100690141 LOC100690141 I3KF49_ORENI I3KF49_ORENI ENSONIP00000045257 ENSONIP00000045257 LOC100705949 LOC100705949 LOC100707447 LOC100707447 ENSONIP00000046720 ENSONIP00000046720 hspb6 hspb6 LOC100702903 LOC100702903 map3k7 map3k7 ENSONIP00000047919 ENSONIP00000047919 LOC100702039 LOC100702039 LOC100693441 LOC100693441 sppl2b sppl2b ikbkb ikbkb ect2 ect2 LOC100689766 LOC100689766 Fgd1 Fgd1 itsn1 itsn1 ENSONIP00000053925 ENSONIP00000053925 Rasgrf2 Rasgrf2 LOC100693794 LOC100693794 LOC100696931 LOC100696931 LOC100698758 LOC100698758 ENSONIP00000057115 ENSONIP00000057115 traf6 traf6 VAV1 VAV1 LOC100706632 LOC100706632 ripk2 ripk2 LOC100700811 LOC100700811 ENSONIP00000058877 ENSONIP00000058877 LOC100712512 LOC100712512 LOC100693402 LOC100693402 ikbkg ikbkg ENSONIP00000060526 ENSONIP00000060526 ENSONIP00000061444 ENSONIP00000061444 LOC100692430 LOC100692430 LOC100695864 LOC100695864 arhgef11 arhgef11 LOC100534558 LOC100534558 Clip3 Clip3 Nfatc4 Nfatc4 LOC100700727 LOC100700727 aph1a aph1a otud1 otud1 tnfaip3 tnfaip3 UBE2D1 UBE2D1 irak1 irak1 madd madd Fadd Fadd LOC100694066 LOC100694066 LOC100705328 LOC100705328 LOC100699327 LOC100699327 I3IWI9_ORENI I3IWI9_ORENI mag mag I3KSR5_ORENI I3KSR5_ORENI mapkapk2 mapkapk2 LOC100692440 LOC100692440 arhgef12 arhgef12 tab1 tab1 mcf2 mcf2 LOC100708948 LOC100708948 LOC100694890 LOC100694890 vav2 vav2 LOC100707473 LOC100707473 LOC100695155 LOC100695155
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100704174LRRNT domain-containing protein. (453 aa)
arhgef37Rho guanine nucleotide exchange factor (GEF) 37. (768 aa)
sqstm1Sequestosome 1. (436 aa)
LOC100697238Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (486 aa)
LOC102083126Uncharacterized protein. (348 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1331 aa)
arhgef10lRho guanine nucleotide exchange factor (GEF) 10-like a. (1288 aa)
LOC100691526TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (266 aa)
LOC100691708Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (305 aa)
arhgef33Rho guanine nucleotide exchange factor (GEF) 33. (808 aa)
ARHGEF2Rho/rac guanine nucleotide exchange factor (GEF) 2. (905 aa)
LOC100534578Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC100707598Si:ch1073-396h14.1. (707 aa)
SPPL2ASignal peptide peptidase like 2A. (538 aa)
arhgef6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (771 aa)
LOC100705827Fas ligand (TNF superfamily, member 6); Belongs to the tumor necrosis factor family. (274 aa)
cyldCylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (956 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (524 aa)
LOC100691403Tax1 (human T-cell leukemia virus type I) binding protein 1b. (821 aa)
LOC100700935ADAM metallopeptidase domain 17a. (851 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1025 aa)
LOC102082089Si:ch73-15b2.5. (549 aa)
arhgef3Rho guanine nucleotide exchange factor (GEF) 3. (676 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
ARHGEF17Rho guanine nucleotide exchange factor (GEF) 17. (2748 aa)
Tiam1T cell lymphoma invasion and metastasis 1b. (1553 aa)
traddTnfrsf1a-associated via death domain. (291 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
LOC100703008Leucine rich repeat and Ig domain containing 1b. (623 aa)
otulinUncharacterized protein. (729 aa)
ENSONIP00000008001E3 ubiquitin-protein ligase RNF31 isoform X1. (1087 aa)
ngefNeuronal guanine nucleotide exchange factor. (767 aa)
LOC100702305Rho guanine nucleotide exchange factor (GEF) 19. (976 aa)
LOC100707250Uncharacterized protein. (1108 aa)
rbck1RanBP-type and C3HC4-type zinc finger containing 1. (519 aa)
sestd1SEC14 and spectrin domains 1. (751 aa)
LOC100705259TNF superfamily member 10, like; Belongs to the tumor necrosis factor family. (332 aa)
trioTrio Rho guanine nucleotide exchange factor a. (3076 aa)
arhgef10Rho guanine nucleotide exchange factor (GEF) 10. (1427 aa)
tiam2T cell lymphoma invasion and metastasis 2a. (1743 aa)
LOC109194206Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (470 aa)
LOC100710405MCF.2 cell line derived transforming sequence b. (1015 aa)
NET1Uncharacterized protein. (583 aa)
LOC100712109Uncharacterized protein; Belongs to the peptidase C14A family. (455 aa)
STUB1STIP1 homology and U-box containing protein 1. (290 aa)
sharpinRanBP2-type domain-containing protein. (436 aa)
LOC100692869Component of inhibitor of nuclear factor kappa B kinase complex. (757 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (678 aa)
LOC100709969Uncharacterized protein. (984 aa)
LOC100704015Rho guanine nucleotide exchange factor (GEF) 1a. (909 aa)
I3JW29_ORENITNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1039 aa)
bag4BCL2 associated athanogene 4. (383 aa)
smpd3Sphingomyelin phosphodiesterase 3, neutral. (699 aa)
LOC100699294Unc-51 like autophagy activating kinase 1a. (905 aa)
LOC100708442TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (598 aa)
LOC100697530Tumor necrosis factor receptor superfamily, member a. (450 aa)
optnOptineurin. (528 aa)
LOC100695566Transmembrane protein 198b. (364 aa)
I3K3K8_ORENICoiled-coil domain containing 28A. (752 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
I3K4Y3_ORENIUncharacterized protein. (493 aa)
casp2Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (525 aa)
I3K566_ORENITumor necrosis factor receptor superfamily, member 1a. (373 aa)
LOC100708196Uncharacterized protein. (1408 aa)
badBCL2 associated agonist of cell death b. (158 aa)
arhgef39Rho guanine nucleotide exchange factor (GEF) 39. (417 aa)
LOC100708611Sharpin and rbck1 related. (708 aa)
smpd2Sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase). (443 aa)
kxd1KxDL motif containing 1. (184 aa)
wdr31WD repeat domain 31. (356 aa)
LOC100702139Uncharacterized protein; Belongs to the peptidase C14A family. (485 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC100706660Uncharacterized protein. (413 aa)
LOC100690570TNF superfamily member 11; Belongs to the tumor necrosis factor family. (267 aa)
prdm4PR domain containing 4. (879 aa)
LOC100701610Baculoviral IAP repeat containing 7. (415 aa)
arhgef38Rho guanine nucleotide exchange factor (GEF) 38. (775 aa)
I3KLZ9_ORENIX-linked inhibitor of apoptosis. (427 aa)
LOC100698148Protein kinase domain-containing protein. (777 aa)
LOC100691909Vav 3 guanine nucleotide exchange factor b. (843 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
ENSONIP00000023653annotation not available (1307 aa)
LOC100700172DH domain-containing protein. (680 aa)
ikbkeInhibitor of nuclear factor kappa B kinase subunit epsilon. (721 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
clip4Uncharacterized protein. (759 aa)
Sos1Son of sevenless homolog 1 (Drosophila). (1401 aa)
rtn1Reticulon. (728 aa)
LOC100696018Leucine rich repeat and Ig domain containing 4b. (604 aa)
LOC100692989Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (296 aa)
LOC106098144Leucine rich repeat and Ig domain containing 4a. (609 aa)
LOC100700742Leucine rich repeat and Ig domain containing 1a. (615 aa)
lingo2Leucine rich repeat and Ig domain containing 2a. (620 aa)
LOC100696124Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (232 aa)
I3KZE4_ORENIApoptosis antagonizing transcription factor. (505 aa)
I3KZF2_ORENILeucine rich repeat and Ig domain containing 2b. (605 aa)
LOC100700983Mcf.2 cell line derived transforming sequence-like a. (1163 aa)
LOC100707993Protein-glutamine gamma-glutamyltransferase 2. (721 aa)
LOC100710620Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (460 aa)
mib2Mindbomb E3 ubiquitin protein ligase 2. (1028 aa)
arhgef7Rho guanine nucleotide exchange factor (GEF) 7a. (862 aa)
arhgef16Rho guanine nucleotide exchange factor (GEF) 16. (705 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (995 aa)
ENSONIP00000034589annotation not available (335 aa)
UBE2D3Ubiquitin conjugating enzyme E2 D3. (151 aa)
LOC100709217Rho guanine nucleotide exchange factor (GEF) 10-like b. (1044 aa)
NCSTNNicastrin. (697 aa)
LOC100689713FYVE, RhoGEF and PH domain containing 3. (917 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1644 aa)
rack1Guanine nucleotide-binding protein subunit beta-2-like 1; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation (By similarity); Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. (323 aa)
otud7bOTU deubiquitinase 7B. (920 aa)
tbk1TANK-binding kinase 1. (746 aa)
I3JS89_ORENIPhosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1604 aa)
ENSONIP00000038243annotation not available (798 aa)
LOC100694779UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
spata2Spermatogenesis associated 2. (568 aa)
LOC100707781TNF superfamily member 10; Belongs to the tumor necrosis factor family. (281 aa)
nsmafNeutral sphingomyelinase (N-SMase) activation associated factor. (925 aa)
LOC100691074Nerve growth factor receptor b. (430 aa)
omgOligodendrocyte-myelin glycoprotein isoform X1. (394 aa)
LOC100693654Uncharacterized protein. (974 aa)
I3JRT5_ORENISi:dkey-38p12.3. (228 aa)
Bcl2l11Bcl-2-like protein 11. (230 aa)
map3k20Uncharacterized protein. (833 aa)
usp4Ubiquitin carboxyl-terminal hydrolase. (999 aa)
LOC100690141Transglutaminase 1 like 1. (803 aa)
I3KF49_ORENICaspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (467 aa)
ENSONIP00000045257Protein-glutamine gamma-glutamyltransferase 2. (404 aa)
LOC100705949Uncharacterized protein. (730 aa)
LOC100707447Transmembrane protein 198a. (390 aa)
ENSONIP00000046720Mucin-12 isoform X6. (1873 aa)
hspb6Heat shock protein, alpha-crystallin-related, b6; Belongs to the small heat shock protein (HSP20) family. (243 aa)
LOC100702903Uncharacterized protein. (203 aa)
map3k7Mitogen-activated protein kinase kinase kinase 7. (686 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
LOC100702039Uncharacterized protein LOC100702039. (392 aa)
LOC100693441FYVE, RhoGEF and PH domain containing 4. (871 aa)
sppl2bSignal peptide peptidase-like 2. (559 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
ect2Epithelial cell transforming 2. (993 aa)
LOC100689766Neuroepithelial cell transforming 1. (628 aa)
Fgd1FYVE, RhoGEF and PH domain containing 1. (929 aa)
itsn1Intersectin 1 (SH3 domain protein). (1795 aa)
ENSONIP00000053925annotation not available (234 aa)
Rasgrf2Ras protein-specific guanine nucleotide-releasing factor 2b. (1249 aa)
LOC100693794Rho guanine nucleotide exchange factor (GEF) 3, like. (522 aa)
LOC100696931Rho guanine nucleotide exchange factor (GEF) 7b. (849 aa)
LOC100698758T cell lymphoma invasion and metastasis 1a. (1674 aa)
ENSONIP00000057115Ubiquitin carboxyl-terminal hydrolase CYLD. (784 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
VAV1Vav guanine nucleotide exchange factor 1. (869 aa)
LOC100706632DUF4203 domain-containing protein. (403 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (570 aa)
LOC100700811Ubiquitin carboxyl-terminal hydrolase CYLD. (701 aa)
ENSONIP00000058877annotation not available (454 aa)
LOC100712512Sterile alpha motif and leucine zipper containing kinase AZK. (668 aa)
LOC100693402DUF4203 domain-containing protein. (371 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (621 aa)
ENSONIP00000060526Si:dkey-181m9.8. (507 aa)
ENSONIP00000061444annotation not available (444 aa)
LOC100692430Transglutaminase 2, C polypeptide A. (718 aa)
LOC100695864Ubiquitin carboxyl-terminal hydrolase. (439 aa)
arhgef11Rho guanine nucleotide exchange factor (GEF) 11. (1448 aa)
LOC100534558Transglutaminase 2, like. (746 aa)
Clip3CAP-GLY domain containing linker protein 3. (673 aa)
Nfatc4Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (974 aa)
LOC100700727Uncharacterized protein. (3151 aa)
aph1aAPH1B gamma secretase subunit. (258 aa)
otud1OTU domain-containing protein 1. (453 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (861 aa)
UBE2D1Ubiquitin-conjugating enzyme E2D 1a; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
irak1Interleukin-1 receptor-associated kinase 1. (752 aa)
maddMAP-kinase activating death domain. (1672 aa)
FaddUncharacterized protein. (209 aa)
LOC100694066Ubiquitin carboxyl-terminal hydrolase 21. (404 aa)
LOC100705328Baculoviral IAP repeat containing 2. (642 aa)
LOC100699327Rho GDP dissociation inhibitor (GDI) alpha. (206 aa)
I3IWI9_ORENINerve growth factor receptor a (TNFR superfamily, member 16). (427 aa)
magMyelin associated glycoprotein. (650 aa)
I3KSR5_ORENIMCF.2 cell line derived transforming sequence-like 2. (1187 aa)
mapkapk2MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (434 aa)
LOC100692440ADAM metallopeptidase domain 17b. (876 aa)
arhgef12Rho guanine nucleotide exchange factor (GEF) 12a. (1413 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (510 aa)
mcf2MCF.2 cell line derived transforming sequence a. (864 aa)
LOC100708948USP domain-containing protein; Belongs to the peptidase C19 family. (602 aa)
LOC100694890Ras protein-specific guanine nucleotide-releasing factor 2a. (1239 aa)
vav2Vav 2 guanine nucleotide exchange factor. (893 aa)
LOC100707473Mcf.2 cell line derived transforming sequence-like b. (1308 aa)
LOC100695155Ubiquitin-conjugating enzyme E2 D2 isoform X1. (181 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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