56 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100691300	Vitellogenin 3, phosvitinless. (1271 aa)
	lsr	Lipolysis stimulated lipoprotein receptor. (625 aa)
	mylip	Myosin regulatory light chain interacting protein a. (481 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (669 aa)
	LOC100698051	Ig-like domain-containing protein. (751 aa)
	LOC100697439	O-acyltransferase. (531 aa)
	nr1h3	Nuclear receptor subfamily 1, group H, member 3. (464 aa)
	LOC100696776	Uncharacterized protein. (406 aa)
	LOC100698692	Uncharacterized protein. (1779 aa)
	I3JKA2_ORENI	Uncharacterized protein. (1781 aa)
	LOC100704334	Low density lipoprotein receptor adaptor protein 1a. (311 aa)
	ldlr	Low density lipoprotein receptor a. (921 aa)
	ldlrap1	Low density lipoprotein receptor adaptor protein 1b. (312 aa)
	npc1	Niemann-Pick disease, type C1. (1273 aa)
	ap2m1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (434 aa)
	LOC100699358	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (559 aa)
	LOC102079941	Apolipoprotein Ba. (4368 aa)
	uba52	Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
	LOC100707019	Uncharacterized protein. (262 aa)
	I3KBD5_ORENI	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (523 aa)
	I3KBH0_ORENI	Vitellogenin domain-containing protein. (736 aa)
	ENSONIP00000018543	annotation not available (519 aa)
	ENSONIP00000018544	annotation not available (512 aa)
	kxd1	KxDL motif containing 1. (184 aa)
	Cubn	Cubilin (intrinsic factor-cobalamin receptor). (3607 aa)
	rps27a	Ribosomal protein S27a. (156 aa)
	LOC100699941	Putative apolipoprotein E. (288 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (230 aa)
	LOC100708634	Apolipoprotein A-Ib. (263 aa)
	LOC100707472	AP complex subunit beta. (953 aa)
	npc2	Niemann-Pick disease, type C2. (147 aa)
	Amn	Amnion associated transmembrane protein. (462 aa)
	LOC100711575	Low-density lipoprotein receptor isoform X2. (1259 aa)
	ENSONIP00000032228	annotation not available (191 aa)
	LOC100691126	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (595 aa)
	Cdcp2	CUB domain containing protein 2. (133 aa)
	Clhc1	Clathrin heavy chain linker domain-containing protein 1 isoform X1. (403 aa)
	I3KSH9_ORENI	Lipase; Belongs to the AB hydrolase superfamily. Lipase family. (484 aa)
	ENSONIP00000047919	Ubiquitin B. (354 aa)
	soat1	O-acyltransferase. (565 aa)
	aadacl4	Arylacetamide deacetylase-like 4. (468 aa)
	vldlr	Very low density lipoprotein receptor. (887 aa)
	ildr2	Immunoglobulin-like domain containing receptor 2. (625 aa)
	LOC100691066	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (586 aa)
	LOC100700052	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
	ENSONIP00000066150	Apolipoprotein C-I. (122 aa)
	LOC100709441	High density lipoprotein binding protein b. (1270 aa)
	pum2	Vitellogenin domain-containing protein. (4590 aa)
	LOC100696314	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (994 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (155 aa)
	hdlbp	High density lipoprotein binding protein a. (1303 aa)
	I3J850_ORENI	COesterase domain-containing protein. (320 aa)
	I3JFT4_ORENI	Uncharacterized protein. (2460 aa)
	scarb1	Scavenger receptor class B, member 1; Belongs to the CD36 family. (537 aa)
	ENSONIP00000075957	Carboxylesterase 5A. (57 aa)
	ENSONIP00000076772	Carboxylesterase 5A. (520 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Amn	Cdcp2	ENSONIP00000026689	ENSONIP00000033750	Amnion associated transmembrane protein.	CUB domain containing protein 2.	0.925
Amn	Cubn	ENSONIP00000026689	ENSONIP00000019007	Amnion associated transmembrane protein.	Cubilin (intrinsic factor-cobalamin receptor).	0.925
Cdcp2	Amn	ENSONIP00000033750	ENSONIP00000026689	CUB domain containing protein 2.	Amnion associated transmembrane protein.	0.925
Clhc1	LOC100700052	ENSONIP00000044814	ENSONIP00000061455	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.822
Clhc1	LOC100707472	ENSONIP00000044814	ENSONIP00000021924	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	AP complex subunit beta.	0.802
Clhc1	ap2m1	ENSONIP00000044814	ENSONIP00000013073	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.786
Clhc1	ap2s1	ENSONIP00000044814	ENSONIP00000070101	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.755
Clhc1	clta	ENSONIP00000044814	ENSONIP00000020435	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.851
Clhc1	pcsk9	ENSONIP00000044814	ENSONIP00000003541	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.420
Clhc1	rps27a	ENSONIP00000044814	ENSONIP00000020250	Clathrin heavy chain linker domain-containing protein 1 isoform X1.	Ribosomal protein S27a.	0.525
Cubn	Amn	ENSONIP00000019007	ENSONIP00000026689	Cubilin (intrinsic factor-cobalamin receptor).	Amnion associated transmembrane protein.	0.925
ENSONIP00000047919	I3JFT4_ORENI	ENSONIP00000047919	ENSONIP00000074065	Ubiquitin B.	Uncharacterized protein.	0.521
ENSONIP00000047919	I3KBH0_ORENI	ENSONIP00000047919	ENSONIP00000018465	Ubiquitin B.	Vitellogenin domain-containing protein.	0.521
ENSONIP00000047919	LOC100696314	ENSONIP00000047919	ENSONIP00000068668	Ubiquitin B.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.618
ENSONIP00000047919	LOC100700052	ENSONIP00000047919	ENSONIP00000061455	Ubiquitin B.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.658
ENSONIP00000047919	LOC100707472	ENSONIP00000047919	ENSONIP00000021924	Ubiquitin B.	AP complex subunit beta.	0.639
ENSONIP00000047919	LOC102079941	ENSONIP00000047919	ENSONIP00000014732	Ubiquitin B.	Apolipoprotein Ba.	0.521
ENSONIP00000047919	ap2m1	ENSONIP00000047919	ENSONIP00000013073	Ubiquitin B.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.673
ENSONIP00000047919	ap2s1	ENSONIP00000047919	ENSONIP00000070101	Ubiquitin B.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.657
ENSONIP00000047919	clta	ENSONIP00000047919	ENSONIP00000020435	Ubiquitin B.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.612