STRINGSTRING
meis1 meis1 LOC100700558 LOC100700558 LOC100695752 LOC100695752 Drap1 Drap1 nedd4l nedd4l SMAD3 SMAD3 ACVR1B ACVR1B I3KPC3_ORENI I3KPC3_ORENI I3KL84_ORENI I3KL84_ORENI LOC100691730 LOC100691730 SMURF2 SMURF2 LOC100705189 LOC100705189 I3IXF2_ORENI I3IXF2_ORENI LOC102075629 LOC102075629 Itgb5 Itgb5 ENSONIP00000067993 ENSONIP00000067993 LOC100699105 LOC100699105 meis2 meis2 grem2 grem2 LOC100705094 LOC100705094 I3JD82_ORENI I3JD82_ORENI sp1 sp1 LOC100705058 LOC100705058 smurf1 smurf1 LOC100691078 LOC100691078 itgb3 itgb3 I3JG35_ORENI I3JG35_ORENI fstl3 fstl3 irx2 irx2 I3JI97_ORENI I3JI97_ORENI NOG NOG LOC100705918 LOC100705918 mkx mkx LOC100710602 LOC100710602 I3K925_ORENI I3K925_ORENI furin furin LOC100705046 LOC100705046 ccnc ccnc LOC100690070 LOC100690070 LOC100708381 LOC100708381 LOC100698783 LOC100698783 ENSONIP00000047919 ENSONIP00000047919 LOC100704395 LOC100704395 LOC100698210 LOC100698210 Bmpr2 Bmpr2 LOC100707005 LOC100707005 LOC100711516 LOC100711516 I3KZC4_ORENI I3KZC4_ORENI LOC100709201 LOC100709201 LOC100699754 LOC100699754 ski ski e2f4 e2f4 ccnq ccnq LOC100706145 LOC100706145 LOC100699888 LOC100699888 LOC100695177 LOC100695177 LOC100690293 LOC100690293 smad6 smad6 arhgef18 arhgef18 LOC100703326 LOC100703326 tgfb2 tgfb2 irx6 irx6 fstl1 fstl1 I3IZA5_ORENI I3IZA5_ORENI men1 men1 zcchc4 zcchc4 FBN1 FBN1 I3KLA2_ORENI I3KLA2_ORENI ldlrad4 ldlrad4 LOC100700968 LOC100700968 LOC100707881 LOC100707881 tgfb3 tgfb3 LOC100701694 LOC100701694 TGFBR2 TGFBR2 LOC100699905 LOC100699905 LOC100696648 LOC100696648 Zfyve9 Zfyve9 LOC100691100 LOC100691100 LOC100703104 LOC100703104 LOC100710680 LOC100710680 LOC100711982 LOC100711982 LOC106098551 LOC106098551 rps27a rps27a LOC100710325 LOC100710325 smad3 smad3 LOC100710008 LOC100710008 LOC100698856 LOC100698856 kxd1 kxd1 LOC100709151 LOC100709151 fst fst tfdp1 tfdp1 cdk8 cdk8 LOC100712573 LOC100712573 LOC100698095 LOC100698095 ncor1 ncor1 strap strap uba52 uba52 smad9 smad9 cdk9 cdk9 LOC100698588 LOC100698588 ACVR2A ACVR2A I3K2K5_ORENI I3K2K5_ORENI I3K2B3_ORENI I3K2B3_ORENI LOC100709139 LOC100709139 I3K1Z3_ORENI I3K1Z3_ORENI LOC100699525 LOC100699525 cdk19 cdk19 I3JZ47_ORENI I3JZ47_ORENI ltbp1 ltbp1 ncor2 ncor2 Itgb8 Itgb8 smad1 smad1 LOC100692645 LOC100692645 STUB1 STUB1 trim33 trim33 acvr1c acvr1c acvr1 acvr1 I3JLM4_ORENI I3JLM4_ORENI LOC100705673 LOC100705673 smad7 smad7 LOC100707272 LOC100707272 cgn cgn LOC100694653 LOC100694653 rnf111 rnf111 I3JEN4_ORENI I3JEN4_ORENI LOC100694986 LOC100694986 LOC100705578 LOC100705578 LOC100690458 LOC100690458 LTBP3 LTBP3 rbl1 rbl1 chrdl2 chrdl2 LOC100703449 LOC100703449 LOC100700916 LOC100700916 bambi bambi PARD3 PARD3 itgb6 itgb6 Irx3 Irx3 irx5 irx5 atp1b4 atp1b4 I3J168_ORENI I3J168_ORENI LOC100711913 LOC100711913 ENSONIP00000001443 ENSONIP00000001443 snw1 snw1 ccnk ccnk LOC100692950 LOC100692950 bmp2 bmp2 parp1 parp1 LOC100697722 LOC100697722 LOC100691573 LOC100691573 usp9x usp9x LOC100690952 LOC100690952 mapk1 mapk1 ENSONIP00000077937 ENSONIP00000077937 amh amh LOC100693777 LOC100693777 I3KQQ1_ORENI I3KQQ1_ORENI ENSONIP00000081242 ENSONIP00000081242
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
meis1Meis homeobox 1 b. (387 aa)
LOC100700558Mothers against decapentaplegic homolog. (550 aa)
LOC100695752Bone morphogenetic protein 10. (480 aa)
Drap1DR1-associated protein 1 (negative cofactor 2 alpha). (222 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1289 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (506 aa)
I3KPC3_ORENIHomeobox domain-containing protein. (355 aa)
I3KL84_ORENIInhibin subunit beta Aa. (427 aa)
LOC100691730Prostate transmembrane protein, androgen induced 1. (325 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
LOC100705189Peptidylprolyl isomerase. (108 aa)
I3IXF2_ORENIPeptidylprolyl isomerase. (119 aa)
LOC102075629Par-3 family cell polarity regulator beta b. (1201 aa)
Itgb5Integrin beta; Belongs to the integrin beta chain family. (817 aa)
ENSONIP00000067993Fibrillin-2 isoform X1. (551 aa)
LOC100699105Integrin beta; Belongs to the integrin beta chain family. (810 aa)
meis2Meis homeobox 2a. (480 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (195 aa)
LOC100705094Mothers against decapentaplegic homolog. (765 aa)
I3JD82_ORENIF11 receptor, tandem duplicate 1. (320 aa)
sp1Sp1 transcription factor. (726 aa)
LOC100705058Inhibin subunit beta B. (404 aa)
smurf1E3 ubiquitin-protein ligase. (745 aa)
LOC100691078E3 ubiquitin-protein ligase. (844 aa)
itgb3Integrin beta; Belongs to the integrin beta chain family. (844 aa)
I3JG35_ORENICbl proto-oncogene, E3 ubiquitin protein ligase. (807 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (278 aa)
irx2Iroquois homeobox 2a. (511 aa)
I3JI97_ORENIHomeobox domain-containing protein. (416 aa)
NOGNoggin 3. (179 aa)
LOC100705918TGFB-induced factor homeobox 1. (330 aa)
mkxMohawk homeobox a. (375 aa)
LOC100710602Cingulin b. (1200 aa)
I3K925_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
furinFurin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
LOC100705046Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
ccncCyclin C; Belongs to the cyclin family. (353 aa)
LOC100690070Cyclin T1; Belongs to the cyclin family. (702 aa)
LOC100708381Mothers against decapentaplegic homolog. (526 aa)
LOC100698783Bone morphogenetic protein 10, like. (458 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
LOC100704395TGF_BETA_2 domain-containing protein. (390 aa)
LOC100698210Cyclin T2; Belongs to the cyclin family. (708 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1033 aa)
LOC100707005Iroquois homeobox 4a. (473 aa)
LOC100711516Ubiquitin-like protein Nedd8. (95 aa)
I3KZC4_ORENIJunB proto-oncogene, AP-1 transcription factor subunit a. (300 aa)
LOC100709201TGF_BETA_2 domain-containing protein. (391 aa)
LOC100699754Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (516 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (740 aa)
e2f4E2F transcription factor 4. (407 aa)
ccnqCyclin Q; Belongs to the cyclin family. (211 aa)
LOC100706145Mothers against decapentaplegic homolog. (481 aa)
LOC100699888STIP1 homology and U-Box containing protein 1. (284 aa)
LOC100695177Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
LOC100690293Ubiquitin-NEDD8-like protein RUB2. (183 aa)
smad6Mothers against decapentaplegic homolog. (488 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1644 aa)
LOC100703326Homeobox protein TGIF2. (578 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
irx6Iroquois homeobox 6a. (498 aa)
fstl1Follistatin-like 1b. (329 aa)
I3IZA5_ORENIMothers against decapentaplegic homolog. (220 aa)
men1Multiple endocrine neoplasia I. (629 aa)
zcchc4Zinc finger, CCHC domain containing 4. (502 aa)
FBN1Fibrillin 1. (2831 aa)
I3KLA2_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (522 aa)
ldlrad4Low density lipoprotein receptor class A domain containing 4b. (297 aa)
LOC100700968Noggin; Belongs to the noggin family. (211 aa)
LOC100707881JunB proto-oncogene, AP-1 transcription factor subunit b. (329 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
LOC100701694Growth differentiation factor 2. (420 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (538 aa)
LOC100699905Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
LOC100696648Mohawk homeobox b. (416 aa)
Zfyve9Zinc finger, FYVE domain containing 9a. (1201 aa)
LOC100691100DAN domain family, member 5. (255 aa)
LOC100703104Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
LOC100710680Myeloid ecotropic viral integration site 3. (418 aa)
LOC100711982Iroquois homeobox 7. (386 aa)
LOC106098551Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (614 aa)
rps27aRibosomal protein S27a. (156 aa)
LOC100710325Mothers against decapentaplegic homolog. (467 aa)
smad3Mothers against decapentaplegic homolog. (448 aa)
LOC100710008Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
LOC100698856Par-3 family cell polarity regulator alpha, b. (1412 aa)
kxd1KxDL motif containing 1. (184 aa)
LOC100709151Forkhead box H1. (514 aa)
fstFollistatin a. (339 aa)
tfdp1Transcription factor. (413 aa)
cdk8Cyclin-dependent kinase 8; Belongs to the protein kinase superfamily. (475 aa)
LOC100712573Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
LOC100698095Mothers against decapentaplegic homolog. (501 aa)
ncor1Nuclear receptor corepressor 1. (2351 aa)
strapSerine/threonine kinase receptor associated protein. (366 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
smad9Mothers against decapentaplegic homolog. (468 aa)
cdk9Cyclin-dependent kinase 9 (CDC2-related kinase); Belongs to the protein kinase superfamily. (393 aa)
LOC100698588Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (506 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
I3K2K5_ORENIUncharacterized protein. (911 aa)
I3K2B3_ORENIReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (505 aa)
LOC100709139Cyclin T2b; Belongs to the cyclin family. (610 aa)
I3K1Z3_ORENIUncharacterized protein. (1603 aa)
LOC100699525Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
cdk19Cyclin-dependent kinase 19; Belongs to the protein kinase superfamily. (492 aa)
I3JZ47_ORENIZinc finger, FYVE domain containing 16. (1400 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1496 aa)
ncor2Nuclear receptor corepressor 2. (2362 aa)
Itgb8Integrin beta; Belongs to the integrin beta chain family. (834 aa)
smad1Mothers against decapentaplegic homolog. (468 aa)
LOC100692645Uncharacterized protein. (863 aa)
STUB1STIP1 homology and U-box containing protein 1. (290 aa)
trim33Tripartite motif containing 33. (1216 aa)
acvr1cReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1280 aa)
I3JLM4_ORENIIroquois homeobox 1b. (184 aa)
LOC100705673Homeobox domain-containing protein. (413 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
LOC100707272Iroquois homeobox 1a. (495 aa)
cgnCingulin a. (1202 aa)
LOC100694653Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
rnf111Ring finger protein 111. (1006 aa)
I3JEN4_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (520 aa)
LOC100694986Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1210 aa)
LOC100705578E2F_TDP domain-containing protein. (79 aa)
LOC100690458Transforming growth factor beta; Belongs to the TGF-beta family. (419 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1239 aa)
rbl1Retinoblastoma-like 1 (p107). (1064 aa)
chrdl2Chordin-like 2. (442 aa)
LOC100703449Par-6 family cell polarity regulator alpha. (530 aa)
LOC100700916V-ski avian sarcoma viral oncogene homolog b. (687 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
PARD3Par-3 family cell polarity regulator. (1376 aa)
itgb6Integrin beta; Belongs to the integrin beta chain family. (781 aa)
Irx3Iroquois homeobox 3a. (433 aa)
irx5Iroquois homeobox 5a. (456 aa)
atp1b4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (343 aa)
I3J168_ORENIZinc finger, FYVE domain containing 9b. (868 aa)
LOC100711913Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
ENSONIP00000001443annotation not available (1468 aa)
snw1SNW domain containing 1. (536 aa)
ccnkCyclin K; Belongs to the cyclin family. (550 aa)
LOC100692950Peptidylprolyl isomerase. (109 aa)
bmp2Bone morphogenetic protein 2b. (418 aa)
parp1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1023 aa)
LOC100697722Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
LOC100691573Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (566 aa)
usp9xUbiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2612 aa)
LOC100690952Meis homeobox 2b. (431 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
ENSONIP00000077937Partitioning defective 3 homolog B isoform X1. (70 aa)
amhAnti-mullerian hormone. (540 aa)
LOC100693777Mothers against decapentaplegic homolog. (500 aa)
I3KQQ1_ORENISKI-like proto-oncogene a. (655 aa)
ENSONIP00000081242Dr1-associated corepressor isoform X1. (149 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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