(6 nodes) TRAF6 mediated IRF7 activation network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100698988	E1A binding protein p300 a. (2777 aa)
	LOC100700725	E1A binding protein p300 b. (2799 aa)
	irf7	Interferon regulatory factor 7. (461 aa)
	Crebbp	CREB binding protein b. (2433 aa)
	LOC100702954	Interferon regulatory factor 3. (466 aa)
	LOC100709989	CREB binding protein a. (2384 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Crebbp	LOC100698988	ENSONIP00000031521	ENSONIP00000072968	CREB binding protein b.	E1A binding protein p300 a.	0.944
Crebbp	LOC100700725	ENSONIP00000031521	ENSONIP00000075311	CREB binding protein b.	E1A binding protein p300 b.	0.942
Crebbp	LOC100702954	ENSONIP00000031521	ENSONIP00000025281	CREB binding protein b.	Interferon regulatory factor 3.	0.967
Crebbp	irf7	ENSONIP00000031521	ENSONIP00000060688	CREB binding protein b.	Interferon regulatory factor 7.	0.743
LOC100698988	Crebbp	ENSONIP00000072968	ENSONIP00000031521	E1A binding protein p300 a.	CREB binding protein b.	0.944
LOC100698988	LOC100702954	ENSONIP00000072968	ENSONIP00000025281	E1A binding protein p300 a.	Interferon regulatory factor 3.	0.940
LOC100698988	LOC100709989	ENSONIP00000072968	ENSONIP00000020562	E1A binding protein p300 a.	CREB binding protein a.	0.942
LOC100698988	irf7	ENSONIP00000072968	ENSONIP00000060688	E1A binding protein p300 a.	Interferon regulatory factor 7.	0.715
LOC100700725	Crebbp	ENSONIP00000075311	ENSONIP00000031521	E1A binding protein p300 b.	CREB binding protein b.	0.942
LOC100700725	LOC100702954	ENSONIP00000075311	ENSONIP00000025281	E1A binding protein p300 b.	Interferon regulatory factor 3.	0.940
LOC100700725	LOC100709989	ENSONIP00000075311	ENSONIP00000020562	E1A binding protein p300 b.	CREB binding protein a.	0.942
LOC100700725	irf7	ENSONIP00000075311	ENSONIP00000060688	E1A binding protein p300 b.	Interferon regulatory factor 7.	0.715
LOC100702954	Crebbp	ENSONIP00000025281	ENSONIP00000031521	Interferon regulatory factor 3.	CREB binding protein b.	0.967
LOC100702954	LOC100698988	ENSONIP00000025281	ENSONIP00000072968	Interferon regulatory factor 3.	E1A binding protein p300 a.	0.940
LOC100702954	LOC100700725	ENSONIP00000025281	ENSONIP00000075311	Interferon regulatory factor 3.	E1A binding protein p300 b.	0.940
LOC100702954	LOC100709989	ENSONIP00000025281	ENSONIP00000020562	Interferon regulatory factor 3.	CREB binding protein a.	0.967
LOC100702954	irf7	ENSONIP00000025281	ENSONIP00000060688	Interferon regulatory factor 3.	Interferon regulatory factor 7.	0.985
LOC100709989	LOC100698988	ENSONIP00000020562	ENSONIP00000072968	CREB binding protein a.	E1A binding protein p300 a.	0.942
LOC100709989	LOC100700725	ENSONIP00000020562	ENSONIP00000075311	CREB binding protein a.	E1A binding protein p300 b.	0.942
LOC100709989	LOC100702954	ENSONIP00000020562	ENSONIP00000025281	CREB binding protein a.	Interferon regulatory factor 3.	0.967