STRINGSTRING
sqstm1 sqstm1 ENSONIP00000000885 ENSONIP00000000885 hdac6 hdac6 LOC100695822 LOC100695822 LOC100709473 LOC100709473 chmp4b chmp4b lamtor2 lamtor2 lamtor5 lamtor5 mterf3 mterf3 dync1li2 dync1li2 rptor rptor I3J608_ORENI I3J608_ORENI atg3 atg3 ulk1 ulk1 txndc11 txndc11 LOC100704732 LOC100704732 TOMM40L TOMM40L LOC100701199 LOC100701199 atm atm LOC100708589 LOC100708589 map1lc3c map1lc3c SRC SRC Prkn Prkn atg4c atg4c LOC100692670 LOC100692670 vim vim mtor mtor LOC100702414 LOC100702414 tomm70 tomm70 TOMM20 TOMM20 ulk2 ulk2 I3JY07_ORENI I3JY07_ORENI LOC100699294 LOC100699294 chmp7 chmp7 csnk2a2 csnk2a2 map1lc3b map1lc3b CRYBB3 CRYBB3 LOC100704877 LOC100704877 prkaa1 prkaa1 atg101 atg101 LOC100698256 LOC100698256 slc38a9 slc38a9 atg14 atg14 FUNDC1 FUNDC1 uba52 uba52 pex5 pex5 LOC100702456 LOC100702456 kxd1 kxd1 I3K2H8_ORENI I3K2H8_ORENI atg13 atg13 rps27a rps27a fundc1 fundc1 becn1 becn1 pink1 pink1 lamtor1 lamtor1 ILRUN ILRUN Atg16l1 Atg16l1 LOC100703206 LOC100703206 chmp2a chmp2a I3KPB3_ORENI I3KPB3_ORENI LOC100709554 LOC100709554 LOC100700174 LOC100700174 mlst8 mlst8 chmp3 chmp3 LOC100712088 LOC100712088 ENSONIP00000025880 ENSONIP00000025880 rb1cc1 rb1cc1 LOC100701181 LOC100701181 I3JTS5_ORENI I3JTS5_ORENI LOC100710962 LOC100710962 DYNC1I1 DYNC1I1 I3IZT9_ORENI I3IZT9_ORENI Mfn2 Mfn2 ENSONIP00000029780 ENSONIP00000029780 vdac1 vdac1 LOC100712348 LOC100712348 LOC100697001 LOC100697001 ENSONIP00000030679 ENSONIP00000030679 ENSONIP00000033379 ENSONIP00000033379 rheb rheb LOC112841648 LOC112841648 uvrag uvrag LOC100704022 LOC100704022 csnk2b csnk2b ENSONIP00000036944 ENSONIP00000036944 LOC102081483 LOC102081483 PRKAB2 PRKAB2 lamtor3 lamtor3 cftr cftr I3JTK2_ORENI I3JTK2_ORENI I3KF91_ORENI I3KF91_ORENI LOC100694867 LOC100694867 ENSONIP00000042545 ENSONIP00000042545 ENSONIP00000042966 ENSONIP00000042966 LOC100708067 LOC100708067 wdr45b wdr45b prkab1 prkab1 I3K989_ORENI I3K989_ORENI LOC100695265 LOC100695265 chmp2b chmp2b LOC100698873 LOC100698873 WIPI1 WIPI1 LOC100696843 LOC100696843 LOC109197098 LOC109197098 ENSONIP00000047919 ENSONIP00000047919 TUBA4A TUBA4A I3IYR9_ORENI I3IYR9_ORENI tube1 tube1 AKAP9 AKAP9 atg5 atg5 cetn3 cetn3 nbr1 nbr1 ENSONIP00000053078 ENSONIP00000053078 LOC100699012 LOC100699012 LOC100704495 LOC100704495 mtmr14 mtmr14 LOC100705156 LOC100705156 atg16l2 atg16l2 arl13b arl13b I3JPB9_ORENI I3JPB9_ORENI tomm6 tomm6 park7 park7 TOMM7 TOMM7 LOC100697765 LOC100697765 tomm22 tomm22 LOC100692677 LOC100692677 LOC109194398 LOC109194398 mfn1 mfn1 pik3c3 pik3c3 LOC100699741 LOC100699741 I3KLA6_ORENI I3KLA6_ORENI prkaa2 prkaa2 ENSONIP00000064133 ENSONIP00000064133 map1lc3a map1lc3a LOC100702273 LOC100702273 GABARAPL2 GABARAPL2 pgam5 pgam5 LOC100698905 LOC100698905 atg4b atg4b LOC100703030 LOC100703030 gabarap gabarap LOC100711021 LOC100711021 LOC100705329 LOC100705329 LOC100696763 LOC100696763 rragc rragc LOC100695572 LOC100695572 ENSONIP00000069794 ENSONIP00000069794 LOC109197651 LOC109197651 ENSONIP00000071086 ENSONIP00000071086 LOC100690967 LOC100690967 lg4h17orf75 lg4h17orf75 ENSONIP00000072381 ENSONIP00000072381 wdr45 wdr45 prkag1 prkag1 tm9sf1 tm9sf1 lamtor4 lamtor4 LOC100691366 LOC100691366 usp30 usp30 Atg12 Atg12 LOC100707887 LOC100707887 LOC100694500 LOC100694500 atg7 atg7 LOC100708734 LOC100708734 LOC100700986 LOC100700986 LOC100710852 LOC100710852 Pwwp2a Pwwp2a tsc2 tsc2 fndc3a fndc3a ENSONIP00000078502 ENSONIP00000078502 TUBA1B TUBA1B LOC100690588 LOC100690588 DYNLL2 DYNLL2 LOC100534434 LOC100534434 atg4d atg4d Pik3r4 Pik3r4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sqstm1Sequestosome 1. (436 aa)
ENSONIP00000000885TSC complex subunit 1a. (924 aa)
hdac6Histone deacetylase 6. (1104 aa)
LOC100695822Centrin 4. (171 aa)
LOC100709473Zgc:109986. (300 aa)
chmp4bCharged multivesicular body protein 4Bb. (222 aa)
lamtor2Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2. (125 aa)
lamtor5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (91 aa)
mterf3Mitochondrial transcription termination factor 3. (428 aa)
dync1li2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (498 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1386 aa)
I3J608_ORENINBR1 autophagy cargo receptor b. (667 aa)
atg3Autophagy-related protein 3. (322 aa)
ulk1Unc-51 like autophagy activating kinase 1. (1025 aa)
txndc11Thioredoxin domain containing 11. (867 aa)
LOC100704732Ras-related GTP binding A. (316 aa)
TOMM40LTranslocase of outer mitochondrial membrane 40 like. (337 aa)
LOC100701199Charged multivesicular body protein 6a. (207 aa)
atmNon-specific serine/threonine protein kinase. (3095 aa)
LOC100708589Charged multivesicular body protein 4C. (218 aa)
map1lc3cMicrotubule-associated protein 1 light chain 3 gamma. (128 aa)
SRCTyrosine-protein kinase. (550 aa)
PrknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (441 aa)
atg4cCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (480 aa)
LOC100692670Ras-related GTP binding D. (416 aa)
vimVimentin like; Belongs to the intermediate filament family. (455 aa)
mtorSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2537 aa)
LOC100702414Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
tomm70Translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae). (579 aa)
TOMM20Translocase of outer mitochondrial membrane 20. (146 aa)
ulk2Unc-51 like autophagy activating kinase 2. (1039 aa)
I3JY07_ORENIGABA(A) receptor-associated protein like 2. (123 aa)
LOC100699294Unc-51 like autophagy activating kinase 1a. (905 aa)
chmp7Charged multivesicular body protein 7. (450 aa)
csnk2a2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (355 aa)
map1lc3bMicrotubule-associated protein 1 light chain 3 beta. (126 aa)
CRYBB3Crystallin beta B3; Belongs to the beta/gamma-crystallin family. (257 aa)
LOC100704877Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (273 aa)
prkaa1Non-specific serine/threonine protein kinase. (580 aa)
atg101Autophagy related 101. (218 aa)
LOC100698256Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (473 aa)
slc38a9Solute carrier family 38 member 9. (558 aa)
atg14Autophagy related 14. (498 aa)
FUNDC1FUN14 domain containing 1. (158 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
pex5Peroxisomal biogenesis factor 5. (680 aa)
LOC100702456Uncharacterized protein. (381 aa)
kxd1KxDL motif containing 1. (184 aa)
I3K2H8_ORENITubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (71 aa)
atg13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (538 aa)
rps27aRibosomal protein S27a. (156 aa)
fundc1Uncharacterized protein. (167 aa)
becn1Beclin 1, autophagy related. (447 aa)
pink1PTEN induced kinase 1. (574 aa)
lamtor1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (160 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (288 aa)
Atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (612 aa)
LOC100703206Uncharacterized protein. (312 aa)
chmp2aCharged multivesicular body protein 2A. (220 aa)
I3KPB3_ORENIAutophagy/beclin-1 regulator 1b. (1278 aa)
LOC100709554Crystallin, gamma N2; Belongs to the beta/gamma-crystallin family. (183 aa)
LOC100700174Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (253 aa)
mlst8MTOR associated protein, LST8 homolog (S. cerevisiae). (327 aa)
chmp3Charged multivesicular body protein 3. (220 aa)
LOC100712088Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (453 aa)
ENSONIP00000025880Tubulin, alpha 4 like. (298 aa)
rb1cc1RB1-inducible coiled-coil 1. (1624 aa)
LOC100701181Microtubule-associated protein 1 light chain 3 gamma, like. (152 aa)
I3JTS5_ORENIProtein kinase, AMP-activated, gamma 2 non-catalytic subunit b. (520 aa)
LOC100710962Casein kinase II subunit beta. (228 aa)
DYNC1I1Dynein cytoplasmic 1 intermediate chain 1. (645 aa)
I3IZT9_ORENIPeroxisomal biogenesis factor 5-like a. (616 aa)
Mfn2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (796 aa)
ENSONIP00000029780annotation not available (203 aa)
vdac1Voltage-dependent anion channel 1. (318 aa)
LOC100712348Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (254 aa)
LOC100697001Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
ENSONIP00000030679annotation not available (116 aa)
ENSONIP00000033379annotation not available (311 aa)
rhebCrystallin, gamma N1; Belongs to the beta/gamma-crystallin family. (330 aa)
LOC112841648Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
uvragUV radiation resistance associated gene. (746 aa)
LOC100704022Tubulin alpha chain-like. (499 aa)
csnk2bCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (233 aa)
ENSONIP00000036944annotation not available (74 aa)
LOC102081483Ubiquitin-conjugating enzyme E2 variant 1. (153 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (270 aa)
lamtor3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (160 aa)
cftrCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1506 aa)
I3JTK2_ORENIATG10 autophagy related 10 homolog (S. cerevisiae). (303 aa)
I3KF91_ORENIIntraflagellar transport 88 homolog. (840 aa)
LOC100694867Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (501 aa)
ENSONIP00000042545annotation not available (145 aa)
ENSONIP00000042966Tubulin, beta 2b. (149 aa)
LOC100708067Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (860 aa)
wdr45bWD repeat domain 45B. (344 aa)
prkab1Protein kinase, AMP-activated, beta 1 non-catalytic subunit, a. (270 aa)
I3K989_ORENIPeroxisomal biogenesis factor 5-like b. (344 aa)
LOC100695265Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
chmp2bCharged multivesicular body protein 2Bb. (214 aa)
LOC100698873Dynein light chain. (89 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (443 aa)
LOC100696843Translocase of outer mitochondrial membrane 40 homolog (yeast). (342 aa)
LOC109197098Tubulin alpha-1A chain isoform X1. (560 aa)
ENSONIP00000047919Ubiquitin B. (354 aa)
TUBA4ATubulin, alpha 8 like 2; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (577 aa)
I3IYR9_ORENIUncharacterized protein. (415 aa)
tube1Tubulin, epsilon 1; Belongs to the tubulin family. (475 aa)
AKAP9A-kinase anchoring protein 9. (4200 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
cetn3Centrin 3. (181 aa)
nbr1NBR1 autophagy cargo receptor a. (1070 aa)
ENSONIP00000053078annotation not available (109 aa)
LOC100699012Fibronectin type III domain containing 3Ba. (1174 aa)
LOC100704495TSC complex subunit 1b. (1275 aa)
mtmr14Myotubularin related protein 14. (700 aa)
LOC100705156Charged multivesicular body protein 6. (205 aa)
atg16l2Autophagy-related protein 16-2 isoform X2. (624 aa)
arl13bADP-ribosylation factor-like 13b. (407 aa)
I3JPB9_ORENIWD repeat domain, phosphoinositide interacting 2. (448 aa)
tomm6Mitochondrial import receptor subunit TOM6 homolog. (64 aa)
park7Parkinson protein 7. (196 aa)
TOMM7Mitochondrial import receptor subunit TOM7 homolog. (87 aa)
LOC100697765Protein kinase, AMP-activated, gamma 3a non-catalytic subunit. (379 aa)
tomm22Translocase of outer mitochondrial membrane 22 homolog (yeast). (133 aa)
LOC100692677Tyrosine-protein kinase. (593 aa)
LOC109194398Tubulin alpha chain-like. (473 aa)
mfn1Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (784 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
LOC100699741UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
I3KLA6_ORENIUncharacterized protein. (780 aa)
prkaa2Non-specific serine/threonine protein kinase. (577 aa)
ENSONIP00000064133annotation not available (110 aa)
map1lc3aMicrotubule-associated protein 1 light chain 3 alpha. (122 aa)
LOC100702273Dynein, cytoplasmic 1, intermediate chain 2a. (647 aa)
GABARAPL2GABA type A receptor associated protein like 2. (126 aa)
pgam5PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (300 aa)
LOC100698905Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (809 aa)
atg4bCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (417 aa)
LOC100703030Translocase of outer mitochondrial membrane 20b. (146 aa)
gabarapGamma-aminobutyric acid receptor-associated protein. (152 aa)
LOC100711021Cysteine protease ATG4D. (459 aa)
LOC100705329Dynein light chain 2, cytoplasmic. (89 aa)
LOC100696763Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (741 aa)
rragcRas-related GTP binding Ca. (382 aa)
LOC100695572Uncharacterized protein. (220 aa)
ENSONIP00000069794Tubulin beta-5 chain. (123 aa)
LOC109197651Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (545 aa)
ENSONIP00000071086Charged multivesicular body protein 4b isoform X2. (230 aa)
LOC100690967Dynein, cytoplasmic 1, intermediate chain 2b. (639 aa)
lg4h17orf75Zgc:153240. (392 aa)
ENSONIP00000072381annotation not available (116 aa)
wdr45WD repeat domain 45. (358 aa)
prkag1Protein kinase, AMP-activated, gamma 1 non-catalytic subunit. (427 aa)
tm9sf1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (609 aa)
lamtor4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (105 aa)
LOC100691366Translocase of outer mitochondrial membrane 40 homolog, like. (385 aa)
usp30Ubiquitin carboxyl-terminal hydrolase. (504 aa)
Atg12Ubiquitin-like protein ATG12. (225 aa)
LOC100707887Mitochondrial import receptor subunit TOM5 homolog isoform X2. (51 aa)
LOC100694500Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (487 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (755 aa)
LOC100708734Inflammation and lipid regulator with UBA-like and NBR1-like domains. (287 aa)
LOC100700986Ras homolog, mTORC1 binding like 1. (184 aa)
LOC100710852Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily. (393 aa)
Pwwp2aPWWP domain containing 2A. (755 aa)
tsc2Rap-GAP domain-containing protein. (1899 aa)
fndc3aFibronectin type III domain containing 3A. (1239 aa)
ENSONIP00000078502annotation not available (107 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (476 aa)
LOC100690588Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (445 aa)
DYNLL2Dynein light chain 2, cytoplasmic. (89 aa)
LOC100534434Zgc:86598; Belongs to the protein kinase superfamily. (392 aa)
atg4dCysteine protease ATG4D. (500 aa)
Pik3r4Phosphoinositide-3-kinase, regulatory subunit 4. (1417 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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