16 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100692564	Tyrosine-protein kinase. (1136 aa)
	hck	Tyrosine-protein kinase. (555 aa)
	elob	Ubiquitin-like domain-containing protein. (122 aa)
	syk	Tyrosine-protein kinase. (615 aa)
	I3JU14_ORENI	Elongin B. (114 aa)
	shc1	SHC (Src homology 2 domain containing) transforming protein 1. (600 aa)
	gab2	GRB2-associated binding protein 2. (654 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	blk	Tyrosine-protein kinase. (523 aa)
	csf3r	Colony stimulating factor 3 receptor (granulocyte). (820 aa)
	LOC100710044	Tyrosine-protein kinase. (1160 aa)
	jak1	Tyrosine-protein kinase. (1183 aa)
	LOC100703251	Interleukin-31 receptor subunit alpha. (812 aa)
	SHC4	SHC adaptor protein 4. (349 aa)
	grb2	Growth factor receptor-bound protein 2b. (222 aa)
	LOC100703836	Zgc:55558. (250 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3JU14_ORENI	elob	ENSONIP00000012359	ENSONIP00000014508	Elongin B.	Ubiquitin-like domain-containing protein.	0.901
LOC100692564	LOC100703251	ENSONIP00000076598	ENSONIP00000056995	Tyrosine-protein kinase.	Interleukin-31 receptor subunit alpha.	0.676
LOC100692564	LOC100710044	ENSONIP00000076598	ENSONIP00000033986	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.901
LOC100692564	SHC4	ENSONIP00000076598	ENSONIP00000058468	Tyrosine-protein kinase.	SHC adaptor protein 4.	0.489
LOC100692564	blk	ENSONIP00000076598	ENSONIP00000019292	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.415
LOC100692564	csf3r	ENSONIP00000076598	ENSONIP00000020463	Tyrosine-protein kinase.	Colony stimulating factor 3 receptor (granulocyte).	0.676
LOC100692564	grb2	ENSONIP00000076598	ENSONIP00000064237	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.653
LOC100692564	hck	ENSONIP00000076598	ENSONIP00000064640	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.415
LOC100692564	jak1	ENSONIP00000076598	ENSONIP00000035176	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.939
LOC100692564	shc1	ENSONIP00000076598	ENSONIP00000007937	Tyrosine-protein kinase.	SHC (Src homology 2 domain containing) transforming protein 1.	0.489
LOC100692564	syk	ENSONIP00000076598	ENSONIP00000014124	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.513
LOC100703251	LOC100692564	ENSONIP00000056995	ENSONIP00000076598	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.676
LOC100703251	LOC100710044	ENSONIP00000056995	ENSONIP00000033986	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.676
LOC100703251	SHC4	ENSONIP00000056995	ENSONIP00000058468	Interleukin-31 receptor subunit alpha.	SHC adaptor protein 4.	0.509
LOC100703251	blk	ENSONIP00000056995	ENSONIP00000019292	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.421
LOC100703251	grb2	ENSONIP00000056995	ENSONIP00000064237	Interleukin-31 receptor subunit alpha.	Growth factor receptor-bound protein 2b.	0.651
LOC100703251	hck	ENSONIP00000056995	ENSONIP00000064640	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.421
LOC100703251	jak1	ENSONIP00000056995	ENSONIP00000035176	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.705
LOC100703251	shc1	ENSONIP00000056995	ENSONIP00000007937	Interleukin-31 receptor subunit alpha.	SHC (Src homology 2 domain containing) transforming protein 1.	0.509
LOC100703251	syk	ENSONIP00000056995	ENSONIP00000014124	Interleukin-31 receptor subunit alpha.	Tyrosine-protein kinase.	0.452