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ap4m1 ap4m1 ap2s1 ap2s1 ap3s2 ap3s2 ap1m1 ap1m1 AP3S1 AP3S1 LOC100699203 LOC100699203 LOC100692268 LOC100692268 AP1S2 AP1S2 LOC100698945 LOC100698945 LOC100711404 LOC100711404 I3JUS7_ORENI I3JUS7_ORENI ap4s1 ap4s1 ap1s1 ap1s1 I3J530_ORENI I3J530_ORENI arcn1 arcn1 LOC100708439 LOC100708439 ap2m1 ap2m1 LOC100705570 LOC100705570
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ap4m1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (413 aa)
ap2s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (155 aa)
ap3s2Adaptor related protein complex 3 subunit sigma 2. (192 aa)
ap1m1AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (452 aa)
AP3S1Adaptor related protein complex 3 subunit sigma 1. (193 aa)
LOC100699203Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (179 aa)
LOC100692268Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. (207 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
LOC100698945AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (428 aa)
LOC100711404Adaptor related protein complex 1 subunit mu 3; Belongs to the adaptor complexes medium subunit family. (433 aa)
I3JUS7_ORENIAP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (163 aa)
ap4s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (193 aa)
ap1s1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
I3J530_ORENIAP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (258 aa)
arcn1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (524 aa)
LOC100708439AP-3 complex subunit mu-2. (439 aa)
ap2m1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (434 aa)
LOC100705570AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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