(29 nodes) (2007) Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni. network (Oreochromis niloticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	hoxb9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (283 aa)
	LOC100709512	Homeobox B13a. (308 aa)
	I3JA92_ORENI	Homeobox A1a. (323 aa)
	Skap2	Src kinase associated phosphoprotein 2. (334 aa)
	LOC100691671	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	LOC100691403	Tax1 (human T-cell leukemia virus type I) binding protein 1b. (821 aa)
	creb5	cAMP responsive element binding protein 5b. (511 aa)
	evx1	Even-skipped homeobox 1. (375 aa)
	cbx1	Chromobox homolog 1b (HP1 beta homolog Drosophila). (179 aa)
	CBX1	Uncharacterized protein. (190 aa)
	lnpk	Limb and neural patterns a. (424 aa)
	LOC100698401	Homeobox B4a. (258 aa)
	NFE2L1	Nuclear factor, erythroid 2 like 1. (802 aa)
	Hoxb5	Homeobox B5b. (316 aa)
	cpvl	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family. (489 aa)
	ENSONIP00000062889	Homeobox protein Hox-B1a-like. (391 aa)
	I3JG07_ORENI	Homeobox B2a. (416 aa)
	LOC100696541	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (329 aa)
	Snx11	Sorting nexin-10/11. (625 aa)
	LOC100702637	Homeobox B6b. (235 aa)
	nfe2	Nuclear factor, erythroid 2. (488 aa)
	cdk5rap3	CDK5 regulatory subunit associated protein 3. (506 aa)
	hoxb1	Homeobox B1b. (286 aa)
	ttll6	Tubulin tyrosine ligase-like family, member 6. (806 aa)
	cbx5	Chromobox homolog 5 (HP1 alpha homolog, Drosophila). (199 aa)
	hoxc13	Homeobox C13a. (302 aa)
	evx2	Even-skipped homeobox 2. (416 aa)
	hoxd3	Homeobox D3a. (399 aa)
	LOC100534461	Homeobox B3a. (486 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBX1	LOC100696541	ENSONIP00000073255	ENSONIP00000047536	Uncharacterized protein.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.400
CBX1	LOC100702637	ENSONIP00000073255	ENSONIP00000034704	Uncharacterized protein.	Homeobox B6b.	0.496
CBX1	NFE2L1	ENSONIP00000073255	ENSONIP00000052955	Uncharacterized protein.	Nuclear factor, erythroid 2 like 1.	0.580
CBX1	Snx11	ENSONIP00000073255	ENSONIP00000045265	Uncharacterized protein.	Sorting nexin-10/11.	0.581
CBX1	cdk5rap3	ENSONIP00000073255	ENSONIP00000022942	Uncharacterized protein.	CDK5 regulatory subunit associated protein 3.	0.581
CBX1	ttll6	ENSONIP00000073255	ENSONIP00000022930	Uncharacterized protein.	Tubulin tyrosine ligase-like family, member 6.	0.581
Hoxb5	I3JG07_ORENI	ENSONIP00000054409	ENSONIP00000064595	Homeobox B5b.	Homeobox B2a.	0.478
Hoxb5	LOC100534461	ENSONIP00000054409	ENSONIP00000007796	Homeobox B5b.	Homeobox B3a.	0.655
Hoxb5	LOC100698401	ENSONIP00000054409	ENSONIP00000047614	Homeobox B5b.	Homeobox B4a.	0.785
Hoxb5	LOC100702637	ENSONIP00000054409	ENSONIP00000034704	Homeobox B5b.	Homeobox B6b.	0.832
Hoxb5	NFE2L1	ENSONIP00000054409	ENSONIP00000052955	Homeobox B5b.	Nuclear factor, erythroid 2 like 1.	0.436
Hoxb5	Snx11	ENSONIP00000054409	ENSONIP00000045265	Homeobox B5b.	Sorting nexin-10/11.	0.427
Hoxb5	hoxb9	ENSONIP00000054409	ENSONIP00000007786	Homeobox B5b.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.658
Hoxb5	ttll6	ENSONIP00000054409	ENSONIP00000022930	Homeobox B5b.	Tubulin tyrosine ligase-like family, member 6.	0.436
I3JA92_ORENI	LOC100696541	ENSONIP00000005782	ENSONIP00000047536	Homeobox A1a.	3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.	0.580
I3JA92_ORENI	lnpk	ENSONIP00000005782	ENSONIP00000076332	Homeobox A1a.	Limb and neural patterns a.	0.452
I3JG07_ORENI	Hoxb5	ENSONIP00000064595	ENSONIP00000054409	Homeobox B2a.	Homeobox B5b.	0.478
I3JG07_ORENI	LOC100534461	ENSONIP00000064595	ENSONIP00000007796	Homeobox B2a.	Homeobox B3a.	0.435
I3JG07_ORENI	LOC100698401	ENSONIP00000064595	ENSONIP00000047614	Homeobox B2a.	Homeobox B4a.	0.413
I3JG07_ORENI	LOC100709512	ENSONIP00000064595	ENSONIP00000007784	Homeobox B2a.	Homeobox B13a.	0.564