(54 nodes) (2015) Characterization of the transcriptome of fast and slow muscle myotomal fibres in the pacu (Piaractus mesopotamicus). network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	I3KBS9_ORENI	Ubiquitin carboxyl-terminal hydrolase. (1003 aa)
	igfbp7	Insulin-like growth factor binding protein 7. (292 aa)
	usp33	Ubiquitin carboxyl-terminal hydrolase. (915 aa)
	usp46	Ubiquitin specific peptidase 46; Belongs to the peptidase C19 family. (370 aa)
	LOC100695864	Ubiquitin carboxyl-terminal hydrolase. (439 aa)
	mstn	Myostatin b. (376 aa)
	myog	Myogenin. (262 aa)
	usp30	Ubiquitin carboxyl-terminal hydrolase. (504 aa)
	myf5	Myogenic factor. (241 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (194 aa)
	EEF1A1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	usp19	Ubiquitin specific peptidase 19. (1517 aa)
	stac3	SH3 and cysteine rich domain 3. (333 aa)
	USP24	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family. (2624 aa)
	LOC100704840	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	LOC100707581	Tyrosine-protein kinase receptor. (1423 aa)
	trip12	Thyroid hormone receptor interactor 12. (2065 aa)
	usp47	Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1383 aa)
	LOC100699569	Calpain 3b; Belongs to the peptidase C2 family. (770 aa)
	LOC100690520	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (456 aa)
	I3JGN5_ORENI	Insulin-like growth factor binding protein 1a. (268 aa)
	usp48	Ubiquitin specific peptidase 48; Belongs to the peptidase C19 family. (1050 aa)
	mtor	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2537 aa)
	LOC100704877	Protein kinase, AMP-activated, beta 1 non-catalytic subunit, b. (273 aa)
	LOC100696646	Insulin-like growth factor binding protein 5a. (269 aa)
	LOC100711993	Tyrosine-protein kinase receptor. (1418 aa)
	usp7	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family. (1115 aa)
	I3KFD8_ORENI	Insulin-like growth factor 2 receptor. (2365 aa)
	RPL19-2	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (197 aa)
	I3KPD3_ORENI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
	fancd2	FA complementation group D2. (1457 aa)
	mdm4	MDM4 regulator of p53; Belongs to the MDM2/MDM4 family. (512 aa)
	mlst8	MTOR associated protein, LST8 homolog (S. cerevisiae). (327 aa)
	usp28	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1231 aa)
	ef-1a	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
	Mb	Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (198 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
	I3JCU4_ORENI	Ubiquitin carboxyl-terminal hydrolase. (1008 aa)
	usp12	Ubiquitin specific peptidase 12a; Belongs to the peptidase C19 family. (374 aa)
	p53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
	usp14	Ubiquitin carboxyl-terminal hydrolase. (544 aa)
	hprt1	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
	usp4	Ubiquitin carboxyl-terminal hydrolase. (999 aa)
	myod1	Myogenic factor. (300 aa)
	LOC100699484	Mitogen-activated protein kinase. (386 aa)
	LOC100709560	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (530 aa)
	LOC100692416	Mitogen-activated protein kinase. (376 aa)
	LOC100696823	Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
	LOC100694444	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (472 aa)
	LOC100699155	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (164 aa)
	capn3	Glucosidase, alpha; neutral C; Belongs to the peptidase C2 family. (721 aa)
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (931 aa)
	gapdhs	Glyceraldehyde-3-phosphate dehydrogenase. (375 aa)
	tsc2	Rap-GAP domain-containing protein. (1899 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EEF1A1	LOC100690520	ENSONIP00000001501	ENSONIP00000007767	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.901
EEF1A1	LOC100696823	ENSONIP00000001501	ENSONIP00000059789	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Glyceraldehyde-3-phosphate dehydrogenase.	0.598
EEF1A1	RPL19	ENSONIP00000001501	ENSONIP00000001138	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.640
EEF1A1	RPL19-2	ENSONIP00000001501	ENSONIP00000020477	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.640
EEF1A1	ef-1a	ENSONIP00000001501	ENSONIP00000031953	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.903
EEF1A1	gapdh	ENSONIP00000001501	ENSONIP00000033368	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Glyceraldehyde-3-phosphate dehydrogenase.	0.598
EEF1A1	gapdhs	ENSONIP00000001501	ENSONIP00000078506	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Glyceraldehyde-3-phosphate dehydrogenase.	0.418
I3JCU4_ORENI	USP24	ENSONIP00000033642	ENSONIP00000003524	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin specific peptidase 24; Belongs to the peptidase C19 family.	0.444
I3JCU4_ORENI	p53	ENSONIP00000033642	ENSONIP00000041809	Ubiquitin carboxyl-terminal hydrolase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.540
I3JCU4_ORENI	trip12	ENSONIP00000033642	ENSONIP00000007095	Ubiquitin carboxyl-terminal hydrolase.	Thyroid hormone receptor interactor 12.	0.560
I3JCU4_ORENI	usp14	ENSONIP00000033642	ENSONIP00000043012	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.590
I3JCU4_ORENI	usp28	ENSONIP00000033642	ENSONIP00000030626	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.	0.620
I3JCU4_ORENI	usp30	ENSONIP00000033642	ENSONIP00000075116	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.447
I3KBS9_ORENI	trip12	ENSONIP00000070983	ENSONIP00000007095	Ubiquitin carboxyl-terminal hydrolase.	Thyroid hormone receptor interactor 12.	0.499
I3KBS9_ORENI	usp14	ENSONIP00000070983	ENSONIP00000043012	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.546
I3KBS9_ORENI	usp28	ENSONIP00000070983	ENSONIP00000030626	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.	0.628
I3KBS9_ORENI	usp30	ENSONIP00000070983	ENSONIP00000075116	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin carboxyl-terminal hydrolase.	0.466
I3KBS9_ORENI	usp7	ENSONIP00000070983	ENSONIP00000019747	Ubiquitin carboxyl-terminal hydrolase.	Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.	0.725
I3KFD8_ORENI	LOC100707581	ENSONIP00000019834	ENSONIP00000003710	Insulin-like growth factor 2 receptor.	Tyrosine-protein kinase receptor.	0.521
I3KFD8_ORENI	LOC100711993	ENSONIP00000019834	ENSONIP00000019021	Insulin-like growth factor 2 receptor.	Tyrosine-protein kinase receptor.	0.584