STRINGSTRING
irak4 irak4 I3JV59_ORENI I3JV59_ORENI SRC SRC LOC100707066 LOC100707066 LOC100705706 LOC100705706 TLR2 TLR2 TLR2-2 TLR2-2 tlr2 tlr2 LOC100695417 LOC100695417 bdnf bdnf TLR2-3 TLR2-3 LOC100692677 LOC100692677 ENSONIP00000063243 ENSONIP00000063243 irak1 irak1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
irak4Interleukin-1 receptor-associated kinase 4. (463 aa)
I3JV59_ORENICaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
SRCTyrosine-protein kinase. (550 aa)
LOC100707066Interleukin-1. (244 aa)
LOC100705706Uncharacterized protein; Belongs to the peptidase C14A family. (273 aa)
TLR2Uncharacterized protein. (787 aa)
TLR2-2Toll-like receptor 2 isoform X1. (786 aa)
tlr2TIR domain-containing protein. (821 aa)
LOC100695417Caspase 3; Belongs to the peptidase C14A family. (287 aa)
bdnfBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (294 aa)
TLR2-3Toll-like receptor 2. (670 aa)
LOC100692677Tyrosine-protein kinase. (593 aa)
ENSONIP00000063243Caspase 3. (299 aa)
irak1Interleukin-1 receptor-associated kinase 1. (752 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.