15 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rps13	Small subunit ribosomal protein S13e. (151 aa)
	RPS29	Ribosomal protein S29. (60 aa)
	Rpl39	Large subunit ribosomal protein L39e. (52 aa)
	rps23	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family. (161 aa)
	ENSONIP00000041950	Ribosomal protein S28. (63 aa)
	p53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
	LOC100707344	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (312 aa)
	RPL5-2	Large subunit ribosomal protein L5e. (316 aa)
	RPL5	Ribosomal protein L5. (299 aa)
	RPL19-2	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (197 aa)
	rpl10a	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family. (217 aa)
	rps25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (128 aa)
	rpl23a	Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (220 aa)
	rpl30	Ribosomal protein L30. (116 aa)
	RPL19	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family. (194 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000041950	LOC100707344	ENSONIP00000041950	ENSONIP00000031418	Ribosomal protein S28.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	0.996
ENSONIP00000041950	RPL19	ENSONIP00000041950	ENSONIP00000001138	Ribosomal protein S28.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.965
ENSONIP00000041950	RPL19-2	ENSONIP00000041950	ENSONIP00000020477	Ribosomal protein S28.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.965
ENSONIP00000041950	RPL5	ENSONIP00000041950	ENSONIP00000030470	Ribosomal protein S28.	Ribosomal protein L5.	0.973
ENSONIP00000041950	RPL5-2	ENSONIP00000041950	ENSONIP00000031331	Ribosomal protein S28.	Large subunit ribosomal protein L5e.	0.973
ENSONIP00000041950	RPS29	ENSONIP00000041950	ENSONIP00000079945	Ribosomal protein S28.	Ribosomal protein S29.	0.996
ENSONIP00000041950	Rpl39	ENSONIP00000041950	ENSONIP00000058926	Ribosomal protein S28.	Large subunit ribosomal protein L39e.	0.989
ENSONIP00000041950	rpl10a	ENSONIP00000041950	ENSONIP00000014935	Ribosomal protein S28.	Ribosomal protein; Belongs to the universal ribosomal protein uL1 family.	0.965
ENSONIP00000041950	rpl23a	ENSONIP00000041950	ENSONIP00000006133	Ribosomal protein S28.	Ribosomal protein L23a; Belongs to the universal ribosomal protein uL23 family.	0.988
ENSONIP00000041950	rpl30	ENSONIP00000041950	ENSONIP00000003346	Ribosomal protein S28.	Ribosomal protein L30.	0.991
ENSONIP00000041950	rps13	ENSONIP00000041950	ENSONIP00000068795	Ribosomal protein S28.	Small subunit ribosomal protein S13e.	0.995
ENSONIP00000041950	rps23	ENSONIP00000041950	ENSONIP00000081239	Ribosomal protein S28.	Ribosomal protein S23; Belongs to the universal ribosomal protein uS12 family.	0.994
ENSONIP00000041950	rps25	ENSONIP00000041950	ENSONIP00000006833	Ribosomal protein S28.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.995
LOC100707344	ENSONIP00000041950	ENSONIP00000031418	ENSONIP00000041950	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Ribosomal protein S28.	0.996
LOC100707344	RPL19	ENSONIP00000031418	ENSONIP00000001138	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.990
LOC100707344	RPL19-2	ENSONIP00000031418	ENSONIP00000020477	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family.	0.990
LOC100707344	RPL5	ENSONIP00000031418	ENSONIP00000030470	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Ribosomal protein L5.	0.988
LOC100707344	RPL5-2	ENSONIP00000031418	ENSONIP00000031331	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Large subunit ribosomal protein L5e.	0.988
LOC100707344	RPS29	ENSONIP00000031418	ENSONIP00000079945	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Ribosomal protein S29.	0.999
LOC100707344	Rpl39	ENSONIP00000031418	ENSONIP00000058926	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	Large subunit ribosomal protein L39e.	0.999