9 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sox11	Transcription factor SOX. (363 aa)
	COX1	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (531 aa)
	plagl2	Pleiomorphic adenoma gene-like 2. (607 aa)
	egr2	Early growth response 2b. (446 aa)
	Tbr1	T-box brain transcription factor 1b. (619 aa)
	CYTB	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (380 aa)
	panx2	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (660 aa)
	Egr3	Early growth response 3. (399 aa)
	hoxc6	Homeobox C6a. (234 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COX1	CYTB	ENSONIP00000032108	ENSONIP00000061682	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.999
COX1	Tbr1	ENSONIP00000032108	ENSONIP00000011228	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	T-box brain transcription factor 1b.	0.434
CYTB	COX1	ENSONIP00000061682	ENSONIP00000032108	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	0.999
CYTB	Egr3	ENSONIP00000061682	ENSONIP00000014796	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	Early growth response 3.	0.460
Egr3	CYTB	ENSONIP00000014796	ENSONIP00000061682	Early growth response 3.	Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.	0.460
Egr3	Tbr1	ENSONIP00000014796	ENSONIP00000011228	Early growth response 3.	T-box brain transcription factor 1b.	0.677
Egr3	egr2	ENSONIP00000014796	ENSONIP00000009118	Early growth response 3.	Early growth response 2b.	0.972
Egr3	hoxc6	ENSONIP00000014796	ENSONIP00000015417	Early growth response 3.	Homeobox C6a.	0.672
Egr3	panx2	ENSONIP00000014796	ENSONIP00000013121	Early growth response 3.	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.	0.553
Egr3	sox11	ENSONIP00000014796	ENSONIP00000025936	Early growth response 3.	Transcription factor SOX.	0.473
Tbr1	COX1	ENSONIP00000011228	ENSONIP00000032108	T-box brain transcription factor 1b.	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	0.434
Tbr1	Egr3	ENSONIP00000011228	ENSONIP00000014796	T-box brain transcription factor 1b.	Early growth response 3.	0.677
Tbr1	egr2	ENSONIP00000011228	ENSONIP00000009118	T-box brain transcription factor 1b.	Early growth response 2b.	0.567
Tbr1	panx2	ENSONIP00000011228	ENSONIP00000013121	T-box brain transcription factor 1b.	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.	0.662
Tbr1	plagl2	ENSONIP00000011228	ENSONIP00000000604	T-box brain transcription factor 1b.	Pleiomorphic adenoma gene-like 2.	0.614
egr2	Egr3	ENSONIP00000009118	ENSONIP00000014796	Early growth response 2b.	Early growth response 3.	0.972
egr2	Tbr1	ENSONIP00000009118	ENSONIP00000011228	Early growth response 2b.	T-box brain transcription factor 1b.	0.567
egr2	hoxc6	ENSONIP00000009118	ENSONIP00000015417	Early growth response 2b.	Homeobox C6a.	0.556
egr2	panx2	ENSONIP00000009118	ENSONIP00000013121	Early growth response 2b.	Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family.	0.514
hoxc6	Egr3	ENSONIP00000015417	ENSONIP00000014796	Homeobox C6a.	Early growth response 3.	0.672