(33 nodes) (2021) Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish. network (Oreochromis niloticus)

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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	LOC100689836	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (257 aa)
	atp5pb	ATP synthase peripheral stalk-membrane subunit b. (292 aa)
	LOC100700520	Transmembrane protein 266. (548 aa)
	lamp1	Lysosomal associated membrane protein 1a. (410 aa)
	LOC100693075	Solute carrier family 45 member 3. (554 aa)
	kcnj5	Potassium inwardly-rectifying channel, subfamily J, member 5. (440 aa)
	htatip2	HIV-1 Tat interactive protein 2. (279 aa)
	LOC102079789	Fibronectin type-III domain-containing protein. (547 aa)
	cldn15	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
	slc45a3	Zgc:77158. (570 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (650 aa)
	tmem268	Uncharacterized protein. (350 aa)
	kcne4	Potassium voltage-gated channel, Isk-related family, member 4. (191 aa)
	tmem266	Transmembrane protein 266. (548 aa)
	ATP6V1C1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (419 aa)
	Cdhr2	Uncharacterized protein. (1179 aa)
	slc35f4	Solute carrier family 35 member F4. (466 aa)
	epo	Erythropoietin; Erythropoietin is the principal hormone involved in the regulation of erythrocyte differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Belongs to the EPO/TPO family. (204 aa)
	atad2	ATPase family AAA domain containing 2. (1515 aa)
	fam136a	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. (758 aa)
	me1	Malic enzyme. (588 aa)
	prkaca	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (380 aa)
	LOC102080697	Putative E3 ubiquitin-protein ligase SH3RF2 isoform X1. (844 aa)
	aldh16a1	Aldehyde dehydrogenase 16 family, member A1. (801 aa)
	LOC100700452	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (377 aa)
	LOC100709092	Solute carrier family 2 member 15b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (518 aa)
	LOC100703537	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
	I3JFA0_ORENI	Ectonucleotide pyrophosphatase/phosphodiesterase 1. (773 aa)
	LOC100708943	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (674 aa)
	TLR8	Toll-like receptor 8. (1037 aa)
	TLR8-2	Toll like receptor 8. (1040 aa)
	TLR8-3	Toll-like receptor 8 isoform X1. (1054 aa)
	Pik3r4	Phosphoinositide-3-kinase, regulatory subunit 4. (1417 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V1C1	LOC100700520	ENSONIP00000020685	ENSONIP00000003148	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Transmembrane protein 266.	0.568
ATP6V1C1	aldh16a1	ENSONIP00000020685	ENSONIP00000037445	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Aldehyde dehydrogenase 16 family, member A1.	0.561
ATP6V1C1	slc35f4	ENSONIP00000020685	ENSONIP00000025399	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Solute carrier family 35 member F4.	0.578
ATP6V1C1	tmem266	ENSONIP00000020685	ENSONIP00000019214	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Transmembrane protein 266.	0.574
Cdhr2	LOC100689836	ENSONIP00000022317	ENSONIP00000003400	Uncharacterized protein.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family.	0.484
Cdhr2	LOC100700520	ENSONIP00000022317	ENSONIP00000003148	Uncharacterized protein.	Transmembrane protein 266.	0.623
Cdhr2	LOC100703537	ENSONIP00000022317	ENSONIP00000042788	Uncharacterized protein.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family.	0.502
Cdhr2	LOC100709092	ENSONIP00000022317	ENSONIP00000041184	Uncharacterized protein.	Solute carrier family 2 member 15b; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.	0.510
Cdhr2	LOC102079789	ENSONIP00000022317	ENSONIP00000010734	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.480
Cdhr2	LOC102080697	ENSONIP00000022317	ENSONIP00000035674	Uncharacterized protein.	Putative E3 ubiquitin-protein ligase SH3RF2 isoform X1.	0.480
Cdhr2	Pik3r4	ENSONIP00000022317	ENSONIP00000081090	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 4.	0.472
Cdhr2	kcne4	ENSONIP00000022317	ENSONIP00000018440	Uncharacterized protein.	Potassium voltage-gated channel, Isk-related family, member 4.	0.506
Cdhr2	slc35f4	ENSONIP00000022317	ENSONIP00000025399	Uncharacterized protein.	Solute carrier family 35 member F4.	0.532
Cdhr2	tmem266	ENSONIP00000022317	ENSONIP00000019214	Uncharacterized protein.	Transmembrane protein 266.	0.623
Cdhr2	tmem268	ENSONIP00000022317	ENSONIP00000016973	Uncharacterized protein.	Uncharacterized protein.	0.665
I3JFA0_ORENI	LOC100693075	ENSONIP00000046980	ENSONIP00000004153	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Solute carrier family 45 member 3.	0.479
I3JFA0_ORENI	LOC100708943	ENSONIP00000046980	ENSONIP00000065514	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.483
I3JFA0_ORENI	atp5pb	ENSONIP00000046980	ENSONIP00000003085	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	ATP synthase peripheral stalk-membrane subunit b.	0.483
I3JFA0_ORENI	fam136a	ENSONIP00000046980	ENSONIP00000027639	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Phosphate transporter; Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.	0.489
I3JFA0_ORENI	kcnj5	ENSONIP00000046980	ENSONIP00000006706	Ectonucleotide pyrophosphatase/phosphodiesterase 1.	Potassium inwardly-rectifying channel, subfamily J, member 5.	0.529