(5 nodes) (2022) Vitamin E performs antioxidant effect via PAP retrograde signaling pathway in Nile tilapia (Oreochromis niloticus). network (Oreochromis niloticus)

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Your Input:
	CUL3	Cullin 3; Belongs to the cullin family. (766 aa)
	keap1	Kelch-like ECH-associated protein 1b. (602 aa)
	Xrn2	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (922 aa)
	xrn1	5'-3' exoribonuclease 1. (1707 aa)
	LOC109194151	CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL3	LOC109194151	ENSONIP00000012629	ENSONIP00000040048	Cullin 3; Belongs to the cullin family.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.900
CUL3	Xrn2	ENSONIP00000012629	ENSONIP00000023567	Cullin 3; Belongs to the cullin family.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.587
CUL3	keap1	ENSONIP00000012629	ENSONIP00000022764	Cullin 3; Belongs to the cullin family.	Kelch-like ECH-associated protein 1b.	0.849
CUL3	xrn1	ENSONIP00000012629	ENSONIP00000036800	Cullin 3; Belongs to the cullin family.	5'-3' exoribonuclease 1.	0.605
LOC109194151	CUL3	ENSONIP00000040048	ENSONIP00000012629	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Cullin 3; Belongs to the cullin family.	0.900
LOC109194151	Xrn2	ENSONIP00000040048	ENSONIP00000023567	CULLIN_2 domain-containing protein; Belongs to the cullin family.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.704
LOC109194151	keap1	ENSONIP00000040048	ENSONIP00000022764	CULLIN_2 domain-containing protein; Belongs to the cullin family.	Kelch-like ECH-associated protein 1b.	0.895
LOC109194151	xrn1	ENSONIP00000040048	ENSONIP00000036800	CULLIN_2 domain-containing protein; Belongs to the cullin family.	5'-3' exoribonuclease 1.	0.716
Xrn2	CUL3	ENSONIP00000023567	ENSONIP00000012629	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Cullin 3; Belongs to the cullin family.	0.587
Xrn2	LOC109194151	ENSONIP00000023567	ENSONIP00000040048	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.704
Xrn2	keap1	ENSONIP00000023567	ENSONIP00000022764	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	Kelch-like ECH-associated protein 1b.	0.475
Xrn2	xrn1	ENSONIP00000023567	ENSONIP00000036800	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	5'-3' exoribonuclease 1.	0.989
keap1	CUL3	ENSONIP00000022764	ENSONIP00000012629	Kelch-like ECH-associated protein 1b.	Cullin 3; Belongs to the cullin family.	0.849
keap1	LOC109194151	ENSONIP00000022764	ENSONIP00000040048	Kelch-like ECH-associated protein 1b.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.895
keap1	Xrn2	ENSONIP00000022764	ENSONIP00000023567	Kelch-like ECH-associated protein 1b.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.475
keap1	xrn1	ENSONIP00000022764	ENSONIP00000036800	Kelch-like ECH-associated protein 1b.	5'-3' exoribonuclease 1.	0.482
xrn1	CUL3	ENSONIP00000036800	ENSONIP00000012629	5'-3' exoribonuclease 1.	Cullin 3; Belongs to the cullin family.	0.605
xrn1	LOC109194151	ENSONIP00000036800	ENSONIP00000040048	5'-3' exoribonuclease 1.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.716
xrn1	Xrn2	ENSONIP00000036800	ENSONIP00000023567	5'-3' exoribonuclease 1.	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.	0.989
xrn1	keap1	ENSONIP00000036800	ENSONIP00000022764	5'-3' exoribonuclease 1.	Kelch-like ECH-associated protein 1b.	0.482