STRINGSTRING
ENSONIP00000063243 ENSONIP00000063243 LOC100534483 LOC100534483 gpx8 gpx8 LOC100694221 LOC100694221 TLR2-3 TLR2-3 gpx7 gpx7 LOC100695417 LOC100695417 tlr2 tlr2 I3J485_ORENI I3J485_ORENI p53 p53 TLR2-2 TLR2-2 I3KYD0_ORENI I3KYD0_ORENI TLR2 TLR2 I3KMJ5_ORENI I3KMJ5_ORENI becn1 becn1 LOC100694932 LOC100694932 LOC100702139 LOC100702139 atf6 atf6 I3J2S4_ORENI I3J2S4_ORENI myd88 myd88 LOC109194206 LOC109194206 GPX2 GPX2 LOC100705706 LOC100705706 Sod2 Sod2 il16 il16 ube2b ube2b I3KF49_ORENI I3KF49_ORENI atf4 atf4 I3JV59_ORENI I3JV59_ORENI atg7 atg7 HSPA8 HSPA8 litaf litaf LOC100692041 LOC100692041 LOC100696271 LOC100696271 LOC100696335 LOC100696335 map1lc3a map1lc3a
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSONIP00000063243Caspase 3. (299 aa)
LOC100534483Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
gpx8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (210 aa)
LOC100694221Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
TLR2-3Toll-like receptor 2. (670 aa)
gpx7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (240 aa)
LOC100695417Caspase 3; Belongs to the peptidase C14A family. (287 aa)
tlr2TIR domain-containing protein. (821 aa)
I3J485_ORENICytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family. (475 aa)
p53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (375 aa)
TLR2-2Toll-like receptor 2 isoform X1. (786 aa)
I3KYD0_ORENIJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
TLR2Uncharacterized protein. (787 aa)
I3KMJ5_ORENIGlutathione peroxidase; Belongs to the glutathione peroxidase family. (138 aa)
becn1Beclin 1, autophagy related. (447 aa)
LOC100694932Glutathione peroxidase; Belongs to the glutathione peroxidase family. (130 aa)
LOC100702139Uncharacterized protein; Belongs to the peptidase C14A family. (485 aa)
atf6Activating transcription factor 6. (651 aa)
I3J2S4_ORENIGlutathione peroxidase; Belongs to the glutathione peroxidase family. (173 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
LOC109194206Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (470 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (232 aa)
LOC100705706Uncharacterized protein; Belongs to the peptidase C14A family. (273 aa)
Sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (294 aa)
il16Uncharacterized protein. (623 aa)
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
I3KF49_ORENICaspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (467 aa)
atf4Activating transcription factor 4a. (726 aa)
I3JV59_ORENICaspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
atg7ATG7 autophagy related 7 homolog (S. cerevisiae). (755 aa)
HSPA8Uncharacterized protein. (664 aa)
litafLipopolysaccharide-induced tumor necrosis factor-alpha factor isoform X1. (284 aa)
LOC100692041Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (107 aa)
LOC100696271Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
LOC100696335Transcription factor EB. (518 aa)
map1lc3aMicrotubule-associated protein 1 light chain 3 alpha. (122 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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