(10 nodes) (2023) Effects of Clostridium butyricum on Growth Performance, Intestinal Health, and Disease Resistance of Hybrid Grouper (Epinephelus fuscoguttatusfemale x E. lanceolatusmale) Fed with Cottonseed Protein Concentrate (CPC) Replacement of Fishmeal. network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102076024	TIR domain-containing protein; Belongs to the Toll-like receptor family. (827 aa)
	LOC100534578	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	LOC100705953	Toll-like receptor 18. (889 aa)
	ace	Angiotensin-converting enzyme. (1296 aa)
	TLR2-3	Toll-like receptor 2. (670 aa)
	LOC109204746	Toll-like receptor 1. (817 aa)
	il-8	Uncharacterized protein. (94 aa)
	tlr2	TIR domain-containing protein. (821 aa)
	TLR2-2	Toll-like receptor 2 isoform X1. (786 aa)
	TLR2	Uncharacterized protein. (787 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100534578	TLR2	ENSONIP00000002809	ENSONIP00000025925	Tumor necrosis factor b (TNF superfamily, member 2).	Uncharacterized protein.	0.438
LOC100534578	TLR2-2	ENSONIP00000002809	ENSONIP00000029726	Tumor necrosis factor b (TNF superfamily, member 2).	Toll-like receptor 2 isoform X1.	0.461
LOC100534578	TLR2-3	ENSONIP00000002809	ENSONIP00000054439	Tumor necrosis factor b (TNF superfamily, member 2).	Toll-like receptor 2.	0.446
LOC100534578	il-8	ENSONIP00000002809	ENSONIP00000045970	Tumor necrosis factor b (TNF superfamily, member 2).	Uncharacterized protein.	0.477
LOC100534578	tlr2	ENSONIP00000002809	ENSONIP00000044084	Tumor necrosis factor b (TNF superfamily, member 2).	TIR domain-containing protein.	0.438
LOC100705953	LOC102076024	ENSONIP00000075939	ENSONIP00000017788	Toll-like receptor 18.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
LOC100705953	LOC109204746	ENSONIP00000075939	ENSONIP00000046292	Toll-like receptor 18.	Toll-like receptor 1.	0.908
LOC102076024	LOC100705953	ENSONIP00000017788	ENSONIP00000075939	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 18.	0.900
LOC102076024	TLR2	ENSONIP00000017788	ENSONIP00000025925	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.900
LOC102076024	TLR2-2	ENSONIP00000017788	ENSONIP00000029726	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 2 isoform X1.	0.900
LOC102076024	TLR2-3	ENSONIP00000017788	ENSONIP00000054439	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 2.	0.900
LOC102076024	tlr2	ENSONIP00000017788	ENSONIP00000044084	TIR domain-containing protein; Belongs to the Toll-like receptor family.	TIR domain-containing protein.	0.900
LOC109204746	LOC100705953	ENSONIP00000046292	ENSONIP00000075939	Toll-like receptor 1.	Toll-like receptor 18.	0.908
LOC109204746	TLR2	ENSONIP00000046292	ENSONIP00000025925	Toll-like receptor 1.	Uncharacterized protein.	0.953
LOC109204746	TLR2-2	ENSONIP00000046292	ENSONIP00000029726	Toll-like receptor 1.	Toll-like receptor 2 isoform X1.	0.953
LOC109204746	TLR2-3	ENSONIP00000046292	ENSONIP00000054439	Toll-like receptor 1.	Toll-like receptor 2.	0.954
LOC109204746	tlr2	ENSONIP00000046292	ENSONIP00000044084	Toll-like receptor 1.	TIR domain-containing protein.	0.955
TLR2	LOC100534578	ENSONIP00000025925	ENSONIP00000002809	Uncharacterized protein.	Tumor necrosis factor b (TNF superfamily, member 2).	0.438
TLR2	LOC102076024	ENSONIP00000025925	ENSONIP00000017788	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
TLR2	LOC109204746	ENSONIP00000025925	ENSONIP00000046292	Uncharacterized protein.	Toll-like receptor 1.	0.953