(13 nodes) (2023) Synbiotic Agents and Their Active Components for Sustainable Aquaculture: Concepts, Action Mechanisms, and Applications. network (Oreochromis niloticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TLR2-3	Toll-like receptor 2. (670 aa)
	LOC100692186	Complement component 3. (1656 aa)
	LOC100709003	Complement component c3b, tandem duplicate 2. (1786 aa)
	LOC100690147	Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (187 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	I3KHS6_ORENI	Uncharacterized protein. (1662 aa)
	I3KHY2_ORENI	Uncharacterized protein. (1602 aa)
	TLR2	Uncharacterized protein. (787 aa)
	TLR2-2	Toll-like receptor 2 isoform X1. (786 aa)
	il10	Interleukin 10. (275 aa)
	tlr2	TIR domain-containing protein. (821 aa)
	LOC109202849	Lysozyme C-like. (235 aa)
	I3K459_ORENI	Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family. (144 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3KHS6_ORENI	il10	ENSONIP00000020671	ENSONIP00000038761	Uncharacterized protein.	Interleukin 10.	0.450
I3KHY2_ORENI	il10	ENSONIP00000020727	ENSONIP00000038761	Uncharacterized protein.	Interleukin 10.	0.450
LOC100690147	il10	ENSONIP00000071979	ENSONIP00000038761	Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family.	Interleukin 10.	0.461
LOC100692186	il10	ENSONIP00000059571	ENSONIP00000038761	Complement component 3.	Interleukin 10.	0.485
TLR2	il10	ENSONIP00000025925	ENSONIP00000038761	Uncharacterized protein.	Interleukin 10.	0.632
TLR2	myd88	ENSONIP00000025925	ENSONIP00000007350	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.980
TLR2-2	il10	ENSONIP00000029726	ENSONIP00000038761	Toll-like receptor 2 isoform X1.	Interleukin 10.	0.632
TLR2-2	myd88	ENSONIP00000029726	ENSONIP00000007350	Toll-like receptor 2 isoform X1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.980
TLR2-3	il10	ENSONIP00000054439	ENSONIP00000038761	Toll-like receptor 2.	Interleukin 10.	0.631
TLR2-3	myd88	ENSONIP00000054439	ENSONIP00000007350	Toll-like receptor 2.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.987
il10	I3KHS6_ORENI	ENSONIP00000038761	ENSONIP00000020671	Interleukin 10.	Uncharacterized protein.	0.450
il10	I3KHY2_ORENI	ENSONIP00000038761	ENSONIP00000020727	Interleukin 10.	Uncharacterized protein.	0.450
il10	LOC100690147	ENSONIP00000038761	ENSONIP00000071979	Interleukin 10.	Lysozyme; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Belongs to the glycosyl hydrolase 22 family.	0.461
il10	LOC100692186	ENSONIP00000038761	ENSONIP00000059571	Interleukin 10.	Complement component 3.	0.485
il10	TLR2	ENSONIP00000038761	ENSONIP00000025925	Interleukin 10.	Uncharacterized protein.	0.632
il10	TLR2-2	ENSONIP00000038761	ENSONIP00000029726	Interleukin 10.	Toll-like receptor 2 isoform X1.	0.632
il10	TLR2-3	ENSONIP00000038761	ENSONIP00000054439	Interleukin 10.	Toll-like receptor 2.	0.631
il10	myd88	ENSONIP00000038761	ENSONIP00000007350	Interleukin 10.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.777
il10	tlr2	ENSONIP00000038761	ENSONIP00000044084	Interleukin 10.	TIR domain-containing protein.	0.632
myd88	TLR2	ENSONIP00000007350	ENSONIP00000025925	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.980