(14 nodes) (2025) A comparative study of the genetically improved Abbassa Nile tilapia strain (GIANT-G9) and a commercial strain in Egypt: growth vs. stress response. network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	GOT1	Aspartate aminotransferase. (410 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	LOC100707066	Interleukin-1. (244 aa)
	LOC100696189	Toll-like receptor 9; Belongs to the Toll-like receptor family. (1078 aa)
	Sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (294 aa)
	I3KLG7_ORENI	Interleukin; Belongs to the IL-15/IL-21 family. (153 aa)
	got1	Aspartate aminotransferase. (414 aa)
	TLR2	Uncharacterized protein. (787 aa)
	TLR2-2	Toll-like receptor 2 isoform X1. (786 aa)
	LOC100705311	Aspartate aminotransferase. (449 aa)
	I3KMU3_ORENI	Insulin-like growth factor 1. (230 aa)
	tlr2	TIR domain-containing protein. (821 aa)
	TLR2-3	Toll-like receptor 2. (670 aa)
	mstn	Myostatin b. (376 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GOT1	LOC100705311	ENSONIP00000000342	ENSONIP00000041827	Aspartate aminotransferase.	Aspartate aminotransferase.	0.966
GOT1	LOC100707066	ENSONIP00000000342	ENSONIP00000010489	Aspartate aminotransferase.	Interleukin-1.	0.431
GOT1	got1	ENSONIP00000000342	ENSONIP00000023097	Aspartate aminotransferase.	Aspartate aminotransferase.	0.900
I3KLG7_ORENI	LOC100707066	ENSONIP00000021962	ENSONIP00000010489	Interleukin; Belongs to the IL-15/IL-21 family.	Interleukin-1.	0.717
I3KLG7_ORENI	TLR2	ENSONIP00000021962	ENSONIP00000025925	Interleukin; Belongs to the IL-15/IL-21 family.	Uncharacterized protein.	0.400
I3KLG7_ORENI	myd88	ENSONIP00000021962	ENSONIP00000007350	Interleukin; Belongs to the IL-15/IL-21 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.405
I3KLG7_ORENI	tlr2	ENSONIP00000021962	ENSONIP00000044084	Interleukin; Belongs to the IL-15/IL-21 family.	TIR domain-containing protein.	0.400
I3KMU3_ORENI	LOC100707066	ENSONIP00000042664	ENSONIP00000010489	Insulin-like growth factor 1.	Interleukin-1.	0.545
I3KMU3_ORENI	TLR2	ENSONIP00000042664	ENSONIP00000025925	Insulin-like growth factor 1.	Uncharacterized protein.	0.468
I3KMU3_ORENI	TLR2-2	ENSONIP00000042664	ENSONIP00000029726	Insulin-like growth factor 1.	Toll-like receptor 2 isoform X1.	0.445
I3KMU3_ORENI	TLR2-3	ENSONIP00000042664	ENSONIP00000054439	Insulin-like growth factor 1.	Toll-like receptor 2.	0.466
I3KMU3_ORENI	mstn	ENSONIP00000042664	ENSONIP00000063349	Insulin-like growth factor 1.	Myostatin b.	0.449
I3KMU3_ORENI	tlr2	ENSONIP00000042664	ENSONIP00000044084	Insulin-like growth factor 1.	TIR domain-containing protein.	0.468
LOC100696189	LOC100707066	ENSONIP00000015638	ENSONIP00000010489	Toll-like receptor 9; Belongs to the Toll-like receptor family.	Interleukin-1.	0.412
LOC100696189	TLR2-3	ENSONIP00000015638	ENSONIP00000054439	Toll-like receptor 9; Belongs to the Toll-like receptor family.	Toll-like receptor 2.	0.492
LOC100696189	myd88	ENSONIP00000015638	ENSONIP00000007350	Toll-like receptor 9; Belongs to the Toll-like receptor family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.982
LOC100705311	GOT1	ENSONIP00000041827	ENSONIP00000000342	Aspartate aminotransferase.	Aspartate aminotransferase.	0.966
LOC100705311	LOC100707066	ENSONIP00000041827	ENSONIP00000010489	Aspartate aminotransferase.	Interleukin-1.	0.531
LOC100705311	got1	ENSONIP00000041827	ENSONIP00000023097	Aspartate aminotransferase.	Aspartate aminotransferase.	0.966
LOC100707066	GOT1	ENSONIP00000010489	ENSONIP00000000342	Interleukin-1.	Aspartate aminotransferase.	0.431