STRINGSTRING
racgap1 racgap1 LOC100701417 LOC100701417 arhgef28 arhgef28 I3JVF4_ORENI I3JVF4_ORENI rassf5 rassf5 cdc42bpa cdc42bpa vav2 vav2 LOC100709065 LOC100709065 LOC100700177 LOC100700177 ARHGEF2 ARHGEF2 LOC100692040 LOC100692040 prkd1 prkd1 I3J098_ORENI I3J098_ORENI I3J0S2_ORENI I3J0S2_ORENI stac3 stac3 Akap13 Akap13 stac stac RASSF1 RASSF1 I3J845_ORENI I3J845_ORENI VAV3 VAV3 UNC13A UNC13A dgkb dgkb LOC100708735 LOC100708735 LOC100699838 LOC100699838 pdzd8 pdzd8 Rock1 Rock1 LOC100704015 LOC100704015 I3JW49_ORENI I3JW49_ORENI ksr2 ksr2 LOC100695337 LOC100695337 I3KC05_ORENI I3KC05_ORENI STAC2 STAC2 dgkh dgkh LOC100709397 LOC100709397 plekhm3 plekhm3 DGKD DGKD prkcq prkcq LOC100703104 LOC100703104 plekhm1 plekhm1 LOC100691909 LOC100691909 LOC100695933 LOC100695933 prkci prkci prkcd prkcd I3KSL0_ORENI I3KSL0_ORENI LOC100701985 LOC100701985 LOC100704408 LOC100704408 I3KTN0_ORENI I3KTN0_ORENI LOC100706106 LOC100706106 LOC100699493 LOC100699493 LOC100695466 LOC100695466 LOC100698058 LOC100698058 braf braf LOC100705628 LOC100705628 LOC100698523 LOC100698523 I3J790_ORENI I3J790_ORENI arhgef18 arhgef18 prkd2 prkd2 rock2 rock2 arhgap45 arhgap45 chn2 chn2 UNC13C UNC13C LOC100698894 LOC100698894 arhgap29 arhgap29 Tns1 Tns1 LOC100691250 LOC100691250 I3K991_ORENI I3K991_ORENI raf1 raf1 Prkca Prkca DGKQ DGKQ LOC100690565 LOC100690565 prkch prkch dgkz dgkz def8 def8 Rasgrp3 Rasgrp3 PRKCB PRKCB I3K5L2_ORENI I3K5L2_ORENI LOC100703205 LOC100703205 VAV1 VAV1 RASGRP1 RASGRP1 PRKD3 PRKD3 I3KG87_ORENI I3KG87_ORENI RASGRP2 RASGRP2 dgke dgke I3KN39_ORENI I3KN39_ORENI rassf3 rassf3 UNC13B UNC13B LOC100692088 LOC100692088
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
racgap1Rac GTPase activating protein 1. (648 aa)
LOC100701417Rho-associated, coiled-coil containing protein kinase 2b; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1515 aa)
arhgef28Rho guanine nucleotide exchange factor (GEF) 28a. (1764 aa)
I3JVF4_ORENIUncharacterized protein. (1632 aa)
rassf5Ras association domain family member 5. (599 aa)
cdc42bpaNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1800 aa)
vav2Vav 2 guanine nucleotide exchange factor. (893 aa)
LOC100709065Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (898 aa)
LOC100700177SH3 and cysteine rich domain 2. (417 aa)
ARHGEF2Rho/rac guanine nucleotide exchange factor (GEF) 2. (905 aa)
LOC100692040Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (764 aa)
prkd1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (898 aa)
I3J098_ORENIUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1952 aa)
I3J0S2_ORENIKinase suppressor of ras 1a. (900 aa)
stac3SH3 and cysteine rich domain 3. (333 aa)
Akap13Si:dkey-172h23.2. (1392 aa)
stacSH3 and cysteine rich domain. (446 aa)
RASSF1Ras association domain family member 1. (365 aa)
I3J845_ORENIRAS guanyl releasing protein 4. (710 aa)
VAV3Vav guanine nucleotide exchange factor 3. (864 aa)
UNC13AUnc-13 homolog A. (1673 aa)
dgkbDiacylglycerol kinase. (783 aa)
LOC100708735Diacylglycerol kinase. (1233 aa)
LOC100699838Chimerin 1. (338 aa)
pdzd8PDZ domain containing 8. (1210 aa)
Rock1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
LOC100704015Rho guanine nucleotide exchange factor (GEF) 1a. (909 aa)
I3JW49_ORENIA-Raf proto-oncogene, serine/threonine kinase. (649 aa)
ksr2Kinase suppressor of ras 2. (958 aa)
LOC100695337Ras association domain family member 1. (359 aa)
I3KC05_ORENIKinase suppressor of ras 1b. (834 aa)
STAC2SH3 and cysteine rich domain 2. (418 aa)
dgkhDiacylglycerol kinase. (1199 aa)
LOC100709397Diacylglycerol kinase. (747 aa)
plekhm3Pleckstrin homology domain containing, family M, member 3. (784 aa)
DGKDDiacylglycerol kinase. (1206 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (720 aa)
LOC100703104Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
plekhm1Pleckstrin homology domain containing, family M (with RUN domain) member 1. (1068 aa)
LOC100691909Vav 3 guanine nucleotide exchange factor b. (843 aa)
LOC100695933Myosin IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1574 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
I3KSL0_ORENISi:ch1073-416j23.1. (397 aa)
LOC100701985Tensin 2b. (1538 aa)
LOC100704408Uncharacterized protein. (634 aa)
I3KTN0_ORENICitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2006 aa)
LOC100706106Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
LOC100699493Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (992 aa)
LOC100695466Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (741 aa)
LOC100698058Myosin IXAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2455 aa)
brafB-Raf proto-oncogene serine/threonine-protein kinase. (852 aa)
LOC100705628Chimerin 1. (482 aa)
LOC100698523Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
I3J790_ORENIDiacylglycerol kinase. (1298 aa)
arhgef18Rho/rac guanine nucleotide exchange factor (GEF) 18b. (1644 aa)
prkd2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (944 aa)
rock2Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1394 aa)
arhgap45Rho GTPase activating protein 45b. (1228 aa)
chn2Chimerin 2. (478 aa)
UNC13CUnc-13 homolog C. (2580 aa)
LOC100698894Diacylglycerol kinase. (899 aa)
arhgap29Rho GTPase activating protein 29a. (1341 aa)
Tns1Tensin 1b. (1788 aa)
LOC100691250Diacylglycerol kinase. (767 aa)
I3K991_ORENIUncharacterized protein. (1429 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (673 aa)
PrkcaProtein kinase C, alpha, a. (674 aa)
DGKQDiacylglycerol kinase. (974 aa)
LOC100690565Rho GTPase activating protein 29b. (1415 aa)
prkchProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
dgkzDiacylglycerol kinase. (1313 aa)
def8Differentially expressed in FDCP 8 homolog. (446 aa)
Rasgrp3RAS guanyl releasing protein 3 (calcium and DAG-regulated). (538 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
I3K5L2_ORENIProtein kinase D4. (728 aa)
LOC100703205Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (842 aa)
VAV1Vav guanine nucleotide exchange factor 1. (869 aa)
RASGRP1RAS guanyl releasing protein 1. (806 aa)
PRKD3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (897 aa)
I3KG87_ORENICitron rho-interacting serine/threonine kinase b. (1683 aa)
RASGRP2RAS guanyl releasing protein 2. (592 aa)
dgkeDiacylglycerol kinase. (576 aa)
I3KN39_ORENIDiacylglycerol kinase. (923 aa)
rassf3Ras association domain family member 3. (410 aa)
UNC13BUnc-13 homolog B. (4602 aa)
LOC100692088Tensin 2a. (1708 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.