(20 nodes) Caspase, interleukin-1 beta converting enzyme (ICE) homologues network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100708116	Uncharacterized protein; Belongs to the peptidase C14A family. (399 aa)
	I3J6Y0_ORENI	Uncharacterized protein; Belongs to the peptidase C14A family. (383 aa)
	I3JNN1_ORENI	Uncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (431 aa)
	LOC109194206	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (470 aa)
	casp2	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (525 aa)
	LOC100702139	Uncharacterized protein; Belongs to the peptidase C14A family. (485 aa)
	ENSONIP00000027805	annotation not available (247 aa)
	I3JDF6_ORENI	Uncharacterized protein; Belongs to the peptidase C14A family. (287 aa)
	I3KF49_ORENI	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (467 aa)
	LOC100695417	Caspase 3; Belongs to the peptidase C14A family. (287 aa)
	LOC100693984	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (311 aa)
	I3J831_ORENI	Uncharacterized protein; Belongs to the peptidase C14A family. (291 aa)
	ENSONIP00000062631	Uncharacterized protein LOC102083232. (269 aa)
	ENSONIP00000063243	Caspase 3. (299 aa)
	I3KLR4_ORENI	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (317 aa)
	casp7	Caspase 7, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (312 aa)
	I3JBT0_ORENI	Uncharacterized protein; Belongs to the peptidase C14A family. (567 aa)
	I3JV59_ORENI	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (282 aa)
	CASP6	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family. (313 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP6	I3KF49_ORENI	ENSONIP00000080701	ENSONIP00000044975	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.507
CASP6	LOC100702139	ENSONIP00000080701	ENSONIP00000019734	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.708
CASP6	LOC109194206	ENSONIP00000080701	ENSONIP00000010781	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.707
CASP6	casp9	ENSONIP00000080701	ENSONIP00000008378	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.640
ENSONIP00000063243	I3JV59_ORENI	ENSONIP00000063243	ENSONIP00000076980	Caspase 3.	Caspase 3, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.902
ENSONIP00000063243	I3KF49_ORENI	ENSONIP00000063243	ENSONIP00000044975	Caspase 3.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.957
ENSONIP00000063243	LOC100695417	ENSONIP00000063243	ENSONIP00000047760	Caspase 3.	Caspase 3; Belongs to the peptidase C14A family.	0.901
ENSONIP00000063243	LOC100702139	ENSONIP00000063243	ENSONIP00000019734	Caspase 3.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.965
ENSONIP00000063243	LOC109194206	ENSONIP00000063243	ENSONIP00000010781	Caspase 3.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.962
ENSONIP00000063243	casp2	ENSONIP00000063243	ENSONIP00000016201	Caspase 3.	Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.521
ENSONIP00000063243	casp9	ENSONIP00000063243	ENSONIP00000008378	Caspase 3.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.969
I3J6Y0_ORENI	I3KF49_ORENI	ENSONIP00000004806	ENSONIP00000044975	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.925
I3J6Y0_ORENI	LOC100702139	ENSONIP00000004806	ENSONIP00000019734	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.929
I3J6Y0_ORENI	LOC109194206	ENSONIP00000004806	ENSONIP00000010781	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.928
I3JBT0_ORENI	I3KF49_ORENI	ENSONIP00000074500	ENSONIP00000044975	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.425
I3JBT0_ORENI	LOC100702139	ENSONIP00000074500	ENSONIP00000019734	Uncharacterized protein; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.425
I3JBT0_ORENI	LOC109194206	ENSONIP00000074500	ENSONIP00000010781	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.425
I3JDF6_ORENI	I3KF49_ORENI	ENSONIP00000028815	ENSONIP00000044975	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.420
I3JNN1_ORENI	I3KF49_ORENI	ENSONIP00000005021	ENSONIP00000044975	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.929
I3JNN1_ORENI	I3KLR4_ORENI	ENSONIP00000005021	ENSONIP00000069292	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 6, apoptosis-related cysteine peptidase a; Belongs to the peptidase C14A family.	0.405