STRINGSTRING
syt1 syt1 RIMS2 RIMS2 LOC106096846 LOC106096846 I3IVE7_ORENI I3IVE7_ORENI ENSONIP00000000682 ENSONIP00000000682 I3IWC0_ORENI I3IWC0_ORENI plcd3 plcd3 PLCB1 PLCB1 LOC100703696 LOC100703696 LOC100689896 LOC100689896 baiap3 baiap3 LOC100692040 LOC100692040 CPNE4 CPNE4 pik3cd pik3cd sytl4 sytl4 Cc2d2a Cc2d2a LOC102077930 LOC102077930 wwc3 wwc3 CPNE9 CPNE9 I3J5Q5_ORENI I3J5Q5_ORENI LOC100693881 LOC100693881 LOC100694155 LOC100694155 LOC102075668 LOC102075668 LOC100701023 LOC100701023 CPNE3 CPNE3 LOC100701839 LOC100701839 LOC100710841 LOC100710841 LOC102078886 LOC102078886 I3J7X0_ORENI I3J7X0_ORENI LOC100705747 LOC100705747 LOC100706270 LOC100706270 rims3 rims3 I3JAK0_ORENI I3JAK0_ORENI UNC13A UNC13A LOC100702345 LOC100702345 plcd1 plcd1 I3JEX3_ORENI I3JEX3_ORENI esyt2 esyt2 Syt7 Syt7 LOC100699476 LOC100699476 I3JMK5_ORENI I3JMK5_ORENI LOC100708879 LOC100708879 syt14 syt14 PLCZ1 PLCZ1 I3JPR2_ORENI I3JPR2_ORENI syt4 syt4 LOC100697163 LOC100697163 I3JS64_ORENI I3JS64_ORENI I3JSD3_ORENI I3JSD3_ORENI syt3 syt3 cpne8 cpne8 pla2g4a pla2g4a LOC100710900 LOC100710900 rab11fip2 rab11fip2 PIK3CA PIK3CA Plcg2 Plcg2 RASAL1 RASAL1 LOC100701038 LOC100701038 cpne2 cpne2 LOC100696329 LOC100696329 I3JZZ7_ORENI I3JZZ7_ORENI LOC100708087 LOC100708087 PLCB2 PLCB2 syt12 syt12 c2cd3 c2cd3 plcb3 plcb3 plcl1 plcl1 cep120 cep120 sytl5 sytl5 LOC100690058 LOC100690058 LOC100710649 LOC100710649 hecw1 hecw1 LOC100712226 LOC100712226 ENSONIP00000019560 ENSONIP00000019560 pik3c2a pik3c2a LOC100705558 LOC100705558 LOC100692390 LOC100692390 LOC100700879 LOC100700879 plcg1 plcg1 LOC100707861 LOC100707861 rpgrip1l rpgrip1l cc2d1b cc2d1b I3KQ65_ORENI I3KQ65_ORENI LOC100702854 LOC100702854 LOC102077238 LOC102077238 LOC100711065 LOC100711065 unc13d unc13d TC2N TC2N LOC100708748 LOC100708748 LOC100704658 LOC100704658 C2CD4C C2CD4C LOC100689725 LOC100689725 LOC109204435 LOC109204435 ENSONIP00000026675 ENSONIP00000026675 rasa3 rasa3 LOC100711626 LOC100711626 LOC100701990 LOC100701990 LOC100701560 LOC100701560 LOC100699493 LOC100699493 LOC100708976 LOC100708976 c2cd5 c2cd5 LOC100695466 LOC100695466 LOC109196446 LOC109196446 dab2ip dab2ip CADPS2 CADPS2 I3JX37_ORENI I3JX37_ORENI LOC100698523 LOC100698523 rgs3 rgs3 cpne1 cpne1 cadps cadps I3JEG4_ORENI I3JEG4_ORENI LOC100690222 LOC100690222 uvrag uvrag LOC106098940 LOC106098940 I3J2C3_ORENI I3J2C3_ORENI UNC13C UNC13C plce1 plce1 mctp1 mctp1 I3KKD0_ORENI I3KKD0_ORENI wwp2 wwp2 LOC100696983 LOC100696983 LOC100702832 LOC100702832 fer1l6 fer1l6 LOC100700693 LOC100700693 LOC100711869 LOC100711869 rasa1 rasa1 I3JMQ0_ORENI I3JMQ0_ORENI I3K991_ORENI I3K991_ORENI PLCB4 PLCB4 Prkca Prkca tollip tollip LOC109202491 LOC109202491 I3K066_ORENI I3K066_ORENI sfxn5 sfxn5 I3JZN3_ORENI I3JZN3_ORENI LOC100698947 LOC100698947 LOC100692421 LOC100692421 I3J7B1_ORENI I3J7B1_ORENI I3JK88_ORENI I3JK88_ORENI LOC100694516 LOC100694516 sytl1 sytl1 prkch prkch I3KNB4_ORENI I3KNB4_ORENI PRKCB PRKCB itsn1 itsn1 I3KDW2_ORENI I3KDW2_ORENI rims4 rims4 LOC100704084 LOC100704084 LOC100710439 LOC100710439 LOC100694718 LOC100694718 LOC100703205 LOC100703205 CPNE3-2 CPNE3-2 LOC100704479 LOC100704479 CC2D1A CC2D1A ENSONIP00000059602 ENSONIP00000059602 otof otof LOC100691757 LOC100691757 I3J454_ORENI I3J454_ORENI LOC100693691 LOC100693691 ABR ABR LOC100694694 LOC100694694 LOC109201077 LOC109201077 LOC100691563 LOC100691563 SYT16 SYT16 RASA2 RASA2 I3J1E9_ORENI I3J1E9_ORENI LOC100691078 LOC100691078 syt10 syt10 smurf1 smurf1 I3IUV1_ORENI I3IUV1_ORENI LOC100697520 LOC100697520 LOC100703201 LOC100703201 cpne7 cpne7 ENSONIP00000067233 ENSONIP00000067233 I3J3N8_ORENI I3J3N8_ORENI I3KSL7_ORENI I3KSL7_ORENI plcd4 plcd4 UNC13B UNC13B LOC100699505 LOC100699505 LOC100698227 LOC100698227 ENSONIP00000068850 ENSONIP00000068850 LOC102080234 LOC102080234 SMURF2 SMURF2 c2cd2 c2cd2 RIMS1 RIMS1 LOC100695353 LOC100695353 I3JVF4_ORENI I3JVF4_ORENI LOC100689910 LOC100689910 SYT8 SYT8 LOC100691877 LOC100691877 pkn2 pkn2 ENSONIP00000077201 ENSONIP00000077201 LOC100707592 LOC100707592 SYDE2 SYDE2 LOC106097889 LOC106097889 LOC100694209 LOC100694209 I3IWR5_ORENI I3IWR5_ORENI LOC100709916 LOC100709916 pkn1 pkn1 CAPN6 CAPN6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
syt1Synaptotagmin Ia. (422 aa)
RIMS2Regulating synaptic membrane exocytosis 2. (1487 aa)
LOC106096846MACPF domain-containing protein. (510 aa)
I3IVE7_ORENIDysferlin, limb girdle muscular dystrophy 2B (autosomal recessive). (2047 aa)
ENSONIP00000000682Intersectin 2a. (1301 aa)
I3IWC0_ORENIOtoferlin b. (1769 aa)
plcd3Phosphoinositide phospholipase C. (791 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1239 aa)
LOC100703696Phosphoinositide phospholipase C. (1214 aa)
LOC1006898961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
baiap3BAI1-associated protein 3. (1176 aa)
LOC100692040Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (764 aa)
CPNE4Copine IVa. (572 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
sytl4Synaptotagmin-like 4. (752 aa)
Cc2d2aCoiled-coil and C2 domain containing 2A. (1606 aa)
LOC102077930Uncharacterized protein. (520 aa)
wwc3WWC family member 3. (1149 aa)
CPNE9Copine family member IX. (571 aa)
I3J5Q5_ORENIRAS protein activator like 3. (1161 aa)
LOC100693881Uncharacterized protein. (633 aa)
LOC100694155Uncharacterized protein. (580 aa)
LOC102075668Uncharacterized protein. (574 aa)
LOC100701023WW domain containing E3 ubiquitin protein ligase 1. (961 aa)
CPNE3Copine 3. (552 aa)
LOC100701839Copine III. (538 aa)
LOC100710841BCR activator of RhoGEF and GTPase. (1381 aa)
LOC102078886Uncharacterized protein. (519 aa)
I3J7X0_ORENIPhosphoinositide phospholipase C. (1199 aa)
LOC100705747Extended synaptotagmin-like protein 3. (850 aa)
LOC100706270Uncharacterized protein. (828 aa)
rims3Regulating synaptic membrane exocytosis 3. (324 aa)
I3JAK0_ORENIUncharacterized protein. (364 aa)
UNC13AUnc-13 homolog A. (1673 aa)
LOC100702345Synaptotagmin IXa. (563 aa)
plcd1Phosphoinositide phospholipase C. (784 aa)
I3JEX3_ORENISynaptotagmin XIVb. (751 aa)
esyt2Extended synaptotagmin-like protein 2b. (891 aa)
Syt7Synaptotagmin VIIb. (662 aa)
LOC100699476Synaptotagmin Va. (410 aa)
I3JMK5_ORENISynaptotagmin XV. (347 aa)
LOC100708879Protein kinase N1b. (956 aa)
syt14Synaptotagmin XIVa. (561 aa)
PLCZ1Phosphoinositide phospholipase C. (543 aa)
I3JPR2_ORENISynaptic Ras GTPase activating protein 1b. (1437 aa)
syt4Synaptotagmin IV. (471 aa)
LOC100697163E3 ubiquitin-protein ligase. (888 aa)
I3JS64_ORENIPerforin 1.3. (566 aa)
I3JSD3_ORENIUncharacterized protein. (420 aa)
syt3Synaptotagmin III. (571 aa)
cpne8Copine 8. (564 aa)
pla2g4aPhospholipase A2. (745 aa)
LOC100710900C2 domain-containing protein. (423 aa)
rab11fip2RAB11 family interacting protein 2 (class I). (466 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
RASAL1RAS protein activator like 1b (GAP1 like). (822 aa)
LOC100701038Synaptotagmin-like protein 2 isoform X2. (1692 aa)
cpne2Copine II. (547 aa)
LOC100696329Protein kinase N3. (900 aa)
I3JZZ7_ORENIDouble C2-like domains, alpha. (423 aa)
LOC100708087Extended synaptotagmin-like protein 1a. (983 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1267 aa)
syt12Synaptotagmin XII. (429 aa)
c2cd3C2 domain containing 3 centriole elongation regulator. (2207 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1261 aa)
plcl1Phosphoinositide phospholipase C. (1163 aa)
cep120Centrosomal protein 120. (995 aa)
sytl5Synaptotagmin-like 5. (678 aa)
LOC100690058Double C2-like domains, delta. (426 aa)
LOC100710649Synaptotagmin Ib. (409 aa)
hecw1Si:ch211-188f17.1. (1649 aa)
LOC100712226Uncharacterized protein. (587 aa)
ENSONIP00000019560Synaptotagmin VIIa. (470 aa)
pik3c2aPhosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1726 aa)
LOC100705558Synaptotagmin VIa. (540 aa)
LOC100692390HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2a. (1442 aa)
LOC100700879Synaptotagmin IIa. (431 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
LOC100707861Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
rpgrip1lRPGRIP1 like. (1233 aa)
cc2d1bCoiled-coil and C2 domain containing 1B. (876 aa)
I3KQ65_ORENIMyoferlin like. (1972 aa)
LOC100702854Si:dkey-19b23.13; Belongs to the peptidase C2 family. (716 aa)
LOC102077238Si:dkey-33c9.6. (853 aa)
LOC1007110651-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1294 aa)
unc13dUnc-13 homolog D (C. elegans). (1115 aa)
TC2NTandem C2 domains, nuclear. (451 aa)
LOC100708748RPGR interacting protein 1. (1045 aa)
LOC100704658Synaptotagmin Vb. (422 aa)
C2CD4CC2 calcium dependent domain containing 4C. (418 aa)
LOC100689725C2 calcium dependent domain containing 4A. (447 aa)
LOC109204435C2 domain-containing protein. (418 aa)
ENSONIP00000026675Protein C2-DOMAIN ABA-RELATED 3. (144 aa)
rasa3RAS p21 protein activator 3. (853 aa)
LOC100711626Myoferlin. (2075 aa)
LOC100701990Phosphoinositide phospholipase C. (1109 aa)
LOC100701560Si:dkey-91m11.5. (1291 aa)
LOC100699493Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (992 aa)
LOC100708976Uncharacterized protein. (1295 aa)
c2cd5C2 calcium dependent domain containing 5. (1090 aa)
LOC100695466Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (741 aa)
LOC109196446C2 domain-containing protein. (128 aa)
dab2ipDAB2 interacting protein b. (1235 aa)
CADPS2Calcium dependent secretion activator 2. (1280 aa)
I3JX37_ORENIRabphilin 3A homolog (mouse), b. (618 aa)
LOC100698523Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
rgs3Regulator of G-protein signaling 3 isoform X1. (1190 aa)
cpne1Copine I. (547 aa)
cadpsCa2+-dependent activator protein for secretion b. (1345 aa)
I3JEG4_ORENINEDD4 E3 ubiquitin protein ligase a. (960 aa)
LOC100690222Uncharacterized protein. (1371 aa)
uvragUV radiation resistance associated gene. (746 aa)
LOC106098940C2 domain-containing protein. (144 aa)
I3J2C3_ORENIUncharacterized protein. (203 aa)
UNC13CUnc-13 homolog C. (2580 aa)
plce1Phospholipase C, epsilon 1. (2342 aa)
mctp1Multiple C2 domains, transmembrane 1a. (890 aa)
I3KKD0_ORENIIntersectin 2b. (1607 aa)
wwp2E3 ubiquitin-protein ligase. (908 aa)
LOC100696983Perforin 1.5. (523 aa)
LOC100702832Uncharacterized protein. (1221 aa)
fer1l6Uncharacterized protein. (1851 aa)
LOC100700693Multiple C2 domains, transmembrane 2b. (882 aa)
LOC100711869Uncharacterized protein. (396 aa)
rasa1RAS p21 protein activator (GTPase activating protein) 1a. (1063 aa)
I3JMQ0_ORENIPhosphoinositide phospholipase C. (777 aa)
I3K991_ORENIUncharacterized protein. (1429 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1209 aa)
PrkcaProtein kinase C, alpha, a. (674 aa)
tollipToll interacting protein. (275 aa)
LOC109202491Perforin-1-like. (520 aa)
I3K066_ORENIPiccolo presynaptic cytomatrix protein a. (4169 aa)
sfxn5RAB11 family interacting protein 5a (class I). (1448 aa)
I3JZN3_ORENIMultiple C2 domains, transmembrane 1b. (786 aa)
LOC100698947Copine-5. (575 aa)
LOC100692421Pore forming protein 1. (708 aa)
I3J7B1_ORENIUncharacterized protein. (1389 aa)
I3JK88_ORENIPhosphoinositide phospholipase C. (774 aa)
LOC100694516Copine-9. (566 aa)
sytl1Uncharacterized protein. (529 aa)
prkchProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
I3KNB4_ORENIPhosphoinositide phospholipase C. (1291 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
itsn1Intersectin 1 (SH3 domain protein). (1795 aa)
I3KDW2_ORENIUncharacterized protein. (1165 aa)
rims4Regulating synaptic membrane exocytosis 4. (271 aa)
LOC100704084Phosphoinositide phospholipase C. (1148 aa)
LOC100710439Uncharacterized protein. (1030 aa)
LOC100694718E3 ubiquitin-protein ligase. (877 aa)
LOC100703205Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (842 aa)
CPNE3-2Copine 3. (596 aa)
LOC100704479Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1072 aa)
CC2D1AC2 domain-containing protein. (1070 aa)
ENSONIP00000059602annotation not available (128 aa)
otofOtoferlin a. (2101 aa)
LOC100691757Phosphoinositide phospholipase C. (774 aa)
I3J454_ORENIRegulating synaptic membrane exocytosis 1a. (1497 aa)
LOC100693691Copine IVb. (582 aa)
ABRABR activator of RhoGEF and GTPase. (1109 aa)
LOC100694694Uncharacterized protein. (596 aa)
LOC109201077Perforin-1-like. (520 aa)
LOC100691563Calpain 5b; Belongs to the peptidase C2 family. (753 aa)
SYT16Synaptotagmin 16. (511 aa)
RASA2RAS p21 protein activator 2. (836 aa)
I3J1E9_ORENISynaptotagmin XIb. (449 aa)
LOC100691078E3 ubiquitin-protein ligase. (844 aa)
syt10Synaptotagmin X. (549 aa)
smurf1E3 ubiquitin-protein ligase. (745 aa)
I3IUV1_ORENIRAS protein activator like 2. (1270 aa)
LOC100697520Extended synaptotagmin-like protein 2a. (934 aa)
LOC100703201Phosphoinositide phospholipase C. (1914 aa)
cpne7Copine VII. (592 aa)
ENSONIP00000067233Copine VIII. (543 aa)
I3J3N8_ORENIUncharacterized protein. (1299 aa)
I3KSL7_ORENIExtended synaptotagmin-like protein 1b. (1644 aa)
plcd4Phosphoinositide phospholipase C. (780 aa)
UNC13BUnc-13 homolog B. (4602 aa)
LOC100699505Uncharacterized protein. (430 aa)
LOC100698227Fer-1 like family member 4. (1863 aa)
ENSONIP00000068850Perforin 1. (275 aa)
LOC102080234Uncharacterized protein. (526 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
c2cd2C2 calcium dependent domain containing 2. (664 aa)
RIMS1Regulating synaptic membrane exocytosis 1. (1578 aa)
LOC100695353Synaptotagmin-5. (505 aa)
I3JVF4_ORENIUncharacterized protein. (1632 aa)
LOC100689910Multiple C2 domains, transmembrane 2a. (1058 aa)
SYT8Synaptotagmin 8. (429 aa)
LOC100691877Copine Va. (577 aa)
pkn2Protein kinase N2. (1030 aa)
ENSONIP00000077201Synaptotagmin-12. (442 aa)
LOC100707592Inositol polyphosphate-4-phosphatase type I Ab. (1025 aa)
SYDE2Synapse defective Rho GTPase homolog 2. (1490 aa)
LOC106097889Protein piccolo isoform X1. (7805 aa)
LOC100694209Synaptotagmin IXb. (527 aa)
I3IWR5_ORENIUncharacterized protein. (932 aa)
LOC100709916Calpain 5a; Belongs to the peptidase C2 family. (657 aa)
pkn1Protein kinase N1a. (953 aa)
CAPN6Calpain 6; Belongs to the peptidase C2 family. (660 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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