(12 nodes) Cytochrome b5-like Heme/Steroid binding domain network (Oreochromis niloticus)

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Predicted Interactions

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Your Input:
	herc2	HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4816 aa)
	Nenf	Neudesin neurotrophic factor; Belongs to the cytochrome b5 family. (190 aa)
	fa2h	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (389 aa)
	LOC100697360	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family. (135 aa)
	LOC100691569	Cytochrome b5 reductase 4. (569 aa)
	pgrmc1	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family. (181 aa)
	LOC100711698	Cytochrome b5 domain containing 2; Belongs to the cytochrome b5 family. (252 aa)
	suox	Sulfite oxidase. (573 aa)
	LOC100697151	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family. (216 aa)
	pgrmc2	Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family. (198 aa)
	LOC100700077	Fatty acid desaturase 2. (452 aa)
	LOC100711554	Cytochrome b5 type B; Belongs to the cytochrome b5 family. (159 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100691569	LOC100697151	ENSONIP00000020838	ENSONIP00000034151	Cytochrome b5 reductase 4.	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	0.860
LOC100691569	LOC100697360	ENSONIP00000020838	ENSONIP00000016836	Cytochrome b5 reductase 4.	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	0.860
LOC100691569	LOC100700077	ENSONIP00000020838	ENSONIP00000056498	Cytochrome b5 reductase 4.	Fatty acid desaturase 2.	0.700
LOC100691569	LOC100711554	ENSONIP00000020838	ENSONIP00000074739	Cytochrome b5 reductase 4.	Cytochrome b5 type B; Belongs to the cytochrome b5 family.	0.860
LOC100691569	fa2h	ENSONIP00000020838	ENSONIP00000013916	Cytochrome b5 reductase 4.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.680
LOC100691569	suox	ENSONIP00000020838	ENSONIP00000024166	Cytochrome b5 reductase 4.	Sulfite oxidase.	0.738
LOC100697151	LOC100691569	ENSONIP00000034151	ENSONIP00000020838	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Cytochrome b5 reductase 4.	0.860
LOC100697151	LOC100700077	ENSONIP00000034151	ENSONIP00000056498	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Fatty acid desaturase 2.	0.424
LOC100697151	fa2h	ENSONIP00000034151	ENSONIP00000013916	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.427
LOC100697151	pgrmc2	ENSONIP00000034151	ENSONIP00000053764	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.	0.407
LOC100697151	suox	ENSONIP00000034151	ENSONIP00000024166	Cytochrome b5 domain containing 1; Belongs to the cytochrome b5 family.	Sulfite oxidase.	0.718
LOC100697360	LOC100691569	ENSONIP00000016836	ENSONIP00000020838	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Cytochrome b5 reductase 4.	0.860
LOC100697360	LOC100700077	ENSONIP00000016836	ENSONIP00000056498	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Fatty acid desaturase 2.	0.424
LOC100697360	LOC100711698	ENSONIP00000016836	ENSONIP00000022079	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Cytochrome b5 domain containing 2; Belongs to the cytochrome b5 family.	0.573
LOC100697360	Nenf	ENSONIP00000016836	ENSONIP00000000539	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Neudesin neurotrophic factor; Belongs to the cytochrome b5 family.	0.506
LOC100697360	fa2h	ENSONIP00000016836	ENSONIP00000013916	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...]	0.427
LOC100697360	pgrmc1	ENSONIP00000016836	ENSONIP00000021860	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Progesterone receptor membrane component 1; Belongs to the cytochrome b5 family.	0.619
LOC100697360	pgrmc2	ENSONIP00000016836	ENSONIP00000053764	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Progesterone receptor membrane component 2; Belongs to the cytochrome b5 family.	0.514
LOC100697360	suox	ENSONIP00000016836	ENSONIP00000024166	Cytochrome b5 type A (microsomal); Belongs to the cytochrome b5 family.	Sulfite oxidase.	0.718
LOC100700077	LOC100691569	ENSONIP00000056498	ENSONIP00000020838	Fatty acid desaturase 2.	Cytochrome b5 reductase 4.	0.700