STRINGSTRING
LOC100695712 LOC100695712 ippk ippk plcd3 plcd3 LOC100706096 LOC100706096 PLCB1 PLCB1 ISYNA1 ISYNA1 LOC100689896 LOC100689896 LOC100691684 LOC100691684 LOC100706781 LOC100706781 LOC100697891 LOC100697891 pik3cd pik3cd LOC100706013 LOC100706013 pi4k2b pi4k2b LOC100705971 LOC100705971 LOC100707403 LOC100707403 plcd1 plcd1 LOC100696589 LOC100696589 cdipt cdipt PIK3CA PIK3CA inpp5e inpp5e Plcg2 Plcg2 PLCB2 PLCB2 pip5kl1 pip5kl1 LOC100701390 LOC100701390 FIG4 FIG4 plcb3 plcb3 pikfyve pikfyve LOC100712427 LOC100712427 pi4ka pi4ka miox miox pik3c2a pik3c2a LOC100707864 LOC100707864 inpp5b inpp5b inppl1 inppl1 inpp4b inpp4b plcg1 plcg1 pi4k2a pi4k2a LOC100707861 LOC100707861 inpp1 inpp1 LOC100711065 LOC100711065 PIP5K1A PIP5K1A LOC100701303 LOC100701303 LOC100702630 LOC100702630 mtmr3 mtmr3 mtmr2 mtmr2 inpp5f inpp5f I3JCX9_ORENI I3JCX9_ORENI Inpp5j Inpp5j plce1 plce1 mtmr6 mtmr6 LOC100701963 LOC100701963 I3JK88_ORENI I3JK88_ORENI ocrl ocrl pik3cg pik3cg mtmr14 mtmr14 LOC100704479 LOC100704479 LOC100701476 LOC100701476 itpka itpka Pip5k1c Pip5k1c LOC100691757 LOC100691757 Pik3cb Pik3cb pik3c3 pik3c3 itpk1 itpk1 Mtm1 Mtm1 I3JZ86_ORENI I3JZ86_ORENI Pip4k2c Pip4k2c tpi tpi LOC100703201 LOC100703201 plcd4 plcd4 LOC100708563 LOC100708563 synj1 synj1 PTEN PTEN ALDH6A1 ALDH6A1 mtmr7 mtmr7 MTMR4 MTMR4 I3JAQ2_ORENI I3JAQ2_ORENI LOC100712230 LOC100712230 LOC100698290 LOC100698290 PIP4K2B PIP4K2B LOC100705399 LOC100705399 LOC100691170 LOC100691170 LOC100700292 LOC100700292 LOC100696029 LOC100696029
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100695712Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (464 aa)
ippkInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (503 aa)
plcd3Phosphoinositide phospholipase C. (791 aa)
LOC100706096Aldedh domain-containing protein. (525 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1239 aa)
ISYNA1Inositol-3-phosphate synthase 1. (553 aa)
LOC1006898961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
LOC100691684Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (834 aa)
LOC100706781Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1106 aa)
LOC100697891Si:dkey-152b24.6. (316 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1041 aa)
LOC100706013Inositol polyphosphate phosphatase-like 1b. (1219 aa)
pi4k2bPhosphatidylinositol 4-kinase type 2 beta. (510 aa)
LOC100705971Kinase; Belongs to the inositol phosphokinase (IPK) family. (688 aa)
LOC100707403Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (936 aa)
plcd1Phosphoinositide phospholipase C. (784 aa)
LOC100696589Inositol-1-monophosphatase. (283 aa)
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (212 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1070 aa)
inpp5eInositol polyphosphate-5-phosphatase E. (641 aa)
Plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1270 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1267 aa)
pip5kl1Phosphatidylinositol-4-phosphate 5-kinase-like 1. (446 aa)
LOC100701390Inositol polyphosphate-5-phosphatase Jb. (697 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (927 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1261 aa)
pikfyvePhosphoinositide kinase, FYVE finger containing. (2087 aa)
LOC100712427Inositol-1-monophosphatase. (282 aa)
pi4kaPhosphatidylinositol 4-kinase, catalytic, alpha b; Belongs to the PI3/PI4-kinase family. (2135 aa)
mioxMyo-inositol oxygenase. (286 aa)
pik3c2aPhosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1726 aa)
LOC100707864Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b. (554 aa)
inpp5bInositol polyphosphate-5-phosphatase B. (905 aa)
inppl1Inositol polyphosphate phosphatase-like 1a. (1248 aa)
inpp4bInositol polyphosphate-4-phosphatase type II B. (958 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
pi4k2aPhosphatidylinositol 4-kinase type 2 alpha. (447 aa)
LOC100707861Zgc:158659; Belongs to the PI3/PI4-kinase family. (1070 aa)
inpp1Si:ch211-160o17.2. (377 aa)
LOC1007110651-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1294 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (577 aa)
LOC100701303Si:dkey-266f7.9. (312 aa)
LOC100702630Inositol polyphosphate-5-phosphatase Kb. (528 aa)
mtmr3Myotubularin related protein 3. (1228 aa)
mtmr2Myotubularin related protein 2. (659 aa)
inpp5fInositol polyphosphate-5-phosphatase F. (1133 aa)
I3JCX9_ORENIKinase; Belongs to the inositol phosphokinase (IPK) family. (317 aa)
Inpp5jInositol polyphosphate-5-phosphatase Ja. (530 aa)
plce1Phospholipase C, epsilon 1. (2342 aa)
mtmr6Myotubularin related protein 6. (663 aa)
LOC100701963Myotubularin related protein 1a. (693 aa)
I3JK88_ORENIPhosphoinositide phospholipase C. (774 aa)
ocrlOCRL inositol polyphosphate-5-phosphatase. (977 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1122 aa)
mtmr14Myotubularin related protein 14. (700 aa)
LOC100704479Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1072 aa)
LOC100701476Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b. (610 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (457 aa)
Pip5k1cPhosphatidylinositol-4-phosphate 5-kinase, type I, gamma a. (648 aa)
LOC100691757Phosphoinositide phospholipase C. (774 aa)
Pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1085 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
itpk1Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (389 aa)
Mtm1Myotubularin 1. (614 aa)
I3JZ86_ORENIPhosphatidylinositol 4-kinase, catalytic, alpha a; Belongs to the PI3/PI4-kinase family. (2085 aa)
Pip4k2cPhosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (473 aa)
tpiTriosephosphate isomerase. (247 aa)
LOC100703201Phosphoinositide phospholipase C. (1914 aa)
plcd4Phosphoinositide phospholipase C. (780 aa)
LOC100708563Inositol polyphosphate-5-phosphatase Ka. (491 aa)
synj1Synaptojanin 1. (1683 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (536 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (519 aa)
mtmr7Myotubularin related protein 7a. (649 aa)
MTMR4Myotubularin related protein 4. (1246 aa)
I3JAQ2_ORENISAC1 like phosphatidylinositide phosphatase a. (616 aa)
LOC100712230Myotubularin related protein 7b. (577 aa)
LOC100698290Phosphatidylinositol-4-phosphate 5-kinase, type I, beta a. (510 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (443 aa)
LOC100705399Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (442 aa)
LOC100691170Kinase; Belongs to the inositol phosphokinase (IPK) family. (765 aa)
LOC100700292Uncharacterized protein; Belongs to the histidine acid phosphatase family. (477 aa)
LOC100696029Triosephosphate isomerase. (248 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.