STRINGSTRING
I3ITT5_ORENI I3ITT5_ORENI EEF1A1 EEF1A1 eif2s2 eif2s2 Tardbp Tardbp nup153 nup153 upf3b upf3b LOC100709252 LOC100709252 LOC100704166 LOC100704166 cyfip1 cyfip1 nup43 nup43 eif2s1 eif2s1 LOC100690520 LOC100690520 eif3j eif3j tgs1 tgs1 upf3a upf3a eif3h eif3h nup188 nup188 xpot xpot nup50 nup50 srrm1 srrm1 nup62 nup62 thoc6 thoc6 casc3 casc3 eif3d eif3d nup205 nup205 LOC100693655 LOC100693655 EIF4G1 EIF4G1 pop5 pop5 sap18 sap18 eif5 eif5 strap strap snupn snupn nup155 nup155 paip1 paip1 elac1 elac1 prmt5 prmt5 gemin4 gemin4 nup35 nup35 gemin5 gemin5 pop1 pop1 LOC100694797 LOC100694797 LOC100707688 LOC100707688 LOC100703628 LOC100703628 aaas aaas LOC100696737 LOC100696737 I3KM31_ORENI I3KM31_ORENI UPF2 UPF2 nup107 nup107 LOC100694078 LOC100694078 LOC100694172 LOC100694172 xpo5 xpo5 eif4ebp2 eif4ebp2 ndc1 ndc1 rpp30 rpp30 magoh magoh LOC100693948 LOC100693948 eif4b eif4b alyref alyref LOC100693928 LOC100693928 LOC100700062 LOC100700062 trnt1 trnt1 rpp38 rpp38 LOC109194537 LOC109194537 phax phax nup88 nup88 LOC100691393 LOC100691393 LOC100711348 LOC100711348 nmd3 nmd3 eif4e2 eif4e2 LOC100709750 LOC100709750 LOC100698415 LOC100698415 eif3b eif3b ran ran ENSONIP00000031680 ENSONIP00000031680 ef-1a ef-1a gemin2 gemin2 nxf1 nxf1 nup85 nup85 eif2b4 eif2b4 LOC100690637 LOC100690637 pym1 pym1 LOC100697848 LOC100697848 elac2 elac2 I3J3L9_ORENI I3J3L9_ORENI LOC100698882 LOC100698882 ENSONIP00000042235 ENSONIP00000042235 eif4e eif4e eif5b eif5b Pop4 Pop4 ENSONIP00000044568 ENSONIP00000044568 eif3i eif3i LOC102080291 LOC102080291 EIF3S5 EIF3S5 LOC100692160 LOC100692160 kpnb1 kpnb1 seh1l seh1l ENSONIP00000046810 ENSONIP00000046810 eif1ax eif1ax nup42 nup42 eif4a3 eif4a3 LOC100692890 LOC100692890 eif2b1 eif2b1 LOC100693841 LOC100693841 nup37 nup37 LOC100703341 LOC100703341 pnn pnn Thoc2 Thoc2 LOC100704901 LOC100704901 LOC100707405 LOC100707405 thoc5 thoc5 nup210 nup210 nup93 nup93 Rpp40 Rpp40 NCBP1 NCBP1 UPF1 UPF1 thoc7 thoc7 nxt2 nxt2 rae1 rae1 I3KNC8_ORENI I3KNC8_ORENI LOC100690783 LOC100690783 LOC100703095 LOC100703095 gle1 gle1 nup160 nup160 ENSONIP00000064374 ENSONIP00000064374 eif4a2 eif4a2 LOC100702522 LOC100702522 ube2i ube2i nup133 nup133 LOC100709166 LOC100709166 rangap1 rangap1 LOC100702413 LOC100702413 thoc3 thoc3 fmr1 fmr1 sumo1 sumo1 Gemin6 Gemin6 ddx20 ddx20 gemin8 gemin8 LOC100691937 LOC100691937 I3J7L1_ORENI I3J7L1_ORENI eif2s3 eif2s3 eif2b5 eif2b5 LOC100694149 LOC100694149 LOC100695556 LOC100695556 rbm8a rbm8a Sec13 Sec13
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
I3ITT5_ORENIExportin 1 (CRM1 homolog, yeast) a. (1075 aa)
EEF1A1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
eif2s2Eukaryotic translation initiation factor 2, subunit 2 beta. (332 aa)
TardbpTAR DNA binding protein, like. (399 aa)
nup153Nucleoporin 153. (1529 aa)
upf3bUPF3B regulator of nonsense mediated mRNA decay. (464 aa)
LOC100709252RRM domain-containing protein. (258 aa)
LOC100704166TAR DNA binding protein. (405 aa)
cyfip1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1269 aa)
nup43Nucleoporin 43. (372 aa)
eif2s1Eukaryotic translation initiation factor 2, subunit 1 alpha b. (315 aa)
LOC100690520Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (456 aa)
eif3jEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (241 aa)
tgs1LYN proto-oncogene, Src family tyrosine kinase. (796 aa)
upf3aUPF3A regulator of nonsense mediated mRNA decay. (463 aa)
eif3hEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (341 aa)
nup188Nucleoporin 188. (1746 aa)
xpotExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (971 aa)
nup50Nucleoporin 50. (468 aa)
srrm1Serine/arginine repetitive matrix 1. (867 aa)
nup62Nsp1_C domain-containing protein. (559 aa)
thoc6THO complex 6. (394 aa)
casc3Casc3 exon junction complex subunit. (817 aa)
eif3dEukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (552 aa)
nup205Nucleoporin 205. (1992 aa)
LOC100693655Uncharacterized protein. (1109 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1739 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (168 aa)
sap18Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (153 aa)
eif5Eukaryotic translation initiation factor 5. (441 aa)
strapSerine/threonine kinase receptor associated protein. (366 aa)
snupnSnurportin-1; Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs. Belongs to the snurportin family. (373 aa)
nup155Nucleoporin 155. (1365 aa)
paip1Poly(A) binding protein interacting protein 1. (448 aa)
elac1ElaC ribonuclease Z 1. (392 aa)
prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (635 aa)
gemin4Gem (nuclear organelle) associated protein 4. (1118 aa)
nup35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (294 aa)
gemin5Gem (nuclear organelle) associated protein 5. (1466 aa)
pop1POP1 homolog, ribonuclease P/MRP subunit. (982 aa)
LOC100694797Translocated promoter region a, nuclear basket protein. (2505 aa)
LOC100707688Zgc:193690. (485 aa)
LOC100703628TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor. (469 aa)
aaasAchalasia, adrenocortical insufficiency, alacrimia. (520 aa)
LOC100696737POM121 transmembrane nucleoporin. (1177 aa)
I3KM31_ORENICytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1262 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1275 aa)
nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (920 aa)
LOC100694078Fragile X mental retardation, autosomal homolog 2. (672 aa)
LOC100694172Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (117 aa)
xpo5Exportin 5. (1221 aa)
eif4ebp2Eukaryotic translation initiation factor 4E binding protein 2. (114 aa)
ndc1NDC1 transmembrane nucleoporin. (666 aa)
rpp30Ribonuclease P/MRP 30 subunit. (301 aa)
magohMago homolog, exon junction complex subunit. (147 aa)
LOC100693948DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast). (483 aa)
eif4bEukaryotic translation initiation factor 4Bb. (667 aa)
alyrefAly/REF export factor. (278 aa)
LOC100693928RRM domain-containing protein. (276 aa)
LOC100700062Ran GTPase activating protein 1b. (577 aa)
trnt1tRNA nucleotidyl transferase, CCA-adding, 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (427 aa)
rpp38Ribonuclease P/MRP 38 subunit. (263 aa)
LOC109194537Ribonuclease P/MRP 25 subunit-like. (221 aa)
phaxPhosphorylated adaptor for RNA export. (409 aa)
nup88Nucleoporin 88. (719 aa)
LOC100691393Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (647 aa)
LOC100711348DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B. (455 aa)
nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (505 aa)
eif4e2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (279 aa)
LOC100709750Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. (238 aa)
LOC100698415RNA-binding protein with serine-rich domain 1. (278 aa)
eif3bEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (699 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (260 aa)
ENSONIP00000031680Nuclear cap-binding protein subunit 2-like. (120 aa)
ef-1aElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
gemin2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (264 aa)
nxf1Zgc:153681. (659 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (652 aa)
eif2b4Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (556 aa)
LOC100690637Small ubiquitin-related modifier. (94 aa)
pym1PYM homolog 1, exon junction complex associated factor. (214 aa)
LOC100697848Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (659 aa)
elac2ElaC ribonuclease Z 2. (853 aa)
I3J3L9_ORENIRibonuclease P and MRP subunit p25, b. (235 aa)
LOC100698882Survival of motor neuron 1, telomeric. (282 aa)
ENSONIP00000042235Ribonuclease P protein subunit p25-like protein. (180 aa)
eif4eEukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (227 aa)
eif5bEukaryotic translation initiation factor 5B. (967 aa)
Pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (211 aa)
ENSONIP00000044568Ribonuclease P protein subunit p14 isoform X2. (131 aa)
eif3iEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (325 aa)
LOC102080291Survival motor neuron protein isoform X1. (371 aa)
EIF3S5Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (349 aa)
LOC100692160Eukaryotic translation initiation factor 4E binding protein 1. (120 aa)
kpnb1Karyopherin (importin) beta 1. (899 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (415 aa)
ENSONIP00000046810Nuclear cap-binding protein subunit 2-like. (91 aa)
eif1axEukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (151 aa)
nup42Nucleoporin 42. (439 aa)
eif4a3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (423 aa)
LOC100692890RAN binding protein 2. (3035 aa)
eif2b1Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (329 aa)
LOC100693841Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. (421 aa)
nup37Nucleoporin 37. (325 aa)
LOC100703341Eukaryotic translation initiation factor 4E binding protein 3. (112 aa)
pnnPinin, desmosome associated protein. (668 aa)
Thoc2THO complex 2. (1503 aa)
LOC100704901Uncharacterized protein. (118 aa)
LOC100707405Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (151 aa)
thoc5THO complex 5. (690 aa)
nup210Nucleoporin 210. (1886 aa)
nup93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (820 aa)
Rpp40Ribonuclease P/MRP 40 subunit. (339 aa)
NCBP1Nuclear cap binding protein subunit 1. (816 aa)
UPF1UPF1 RNA helicase and ATPase. (1118 aa)
thoc7THO complex 7. (215 aa)
nxt2Nuclear transport factor 2-like export factor 2. (143 aa)
rae1Ribonucleic acid export 1. (398 aa)
I3KNC8_ORENIUncharacterized protein. (1152 aa)
LOC100690783Uncharacterized protein. (1682 aa)
LOC100703095Exportin 1 (CRM1 homolog, yeast) b. (1083 aa)
gle1GLE1 RNA export mediator. (717 aa)
nup160Nucleoporin 160. (1399 aa)
ENSONIP00000064374Small ubiquitin-related modifier 2. (90 aa)
eif4a2Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. (411 aa)
LOC100702522Eukaryotic translation initiation factor 1B. (136 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
nup133Nucleoporin 133. (1135 aa)
LOC100709166Small ubiquitin-related modifier. (94 aa)
rangap1RAN GTPase activating protein 1a. (582 aa)
LOC100702413Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
thoc3THO complex 3. (327 aa)
fmr1Fragile X mental retardation 1. (600 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
Gemin6Gem (nuclear organelle) associated protein 6. (82 aa)
ddx20DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (827 aa)
gemin8Gem (nuclear organelle) associated protein 8. (209 aa)
LOC100691937Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (461 aa)
I3J7L1_ORENIEukaryotic translation initiation factor 4, gamma 2b. (898 aa)
eif2s3Eukaryotic translation initiation factor 2, subunit 3 gamma. (476 aa)
eif2b5Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (709 aa)
LOC100694149Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (462 aa)
LOC100695556Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (215 aa)
rbm8aRNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (175 aa)
Sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (326 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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