STRINGSTRING
ube2j1 ube2j1 LOC100698375 LOC100698375 ube4b ube4b anapc4 anapc4 LOC100702935 LOC100702935 ube2z ube2z LOC100701023 LOC100701023 cul2 cul2 UBE3A UBE3A LOC100709870 LOC100709870 LOC100702014 LOC100702014 herc2 herc2 trip12 trip12 rnf7 rnf7 ube3c ube3c Prkn Prkn Birc6 Birc6 rbx1 rbx1 LOC100705137 LOC100705137 ube2k ube2k cdc27 cdc27 LOC100697163 LOC100697163 ube2m ube2m STUB1 STUB1 Anapc2 Anapc2 LOC100692645 LOC100692645 I3JU14_ORENI I3JU14_ORENI cdc20 cdc20 CUL3 CUL3 FZR1 FZR1 fbxw8 fbxw8 anapc5 anapc5 skp2 skp2 LOC100699525 LOC100699525 elob elob ube2h ube2h anapc10 anapc10 huwe1 huwe1 MID1 MID1 uba52 uba52 Ube2s Ube2s ube2l3 ube2l3 Ube2w Ube2w fbxo4 fbxo4 pias1 pias1 Ddb2 Ddb2 I3KEF4_ORENI I3KEF4_ORENI LOC100694898 LOC100694898 LOC100704232 LOC100704232 Rchy1 Rchy1 anapc7 anapc7 ENSONIP00000020099 ENSONIP00000020099 rps27a rps27a brca1 brca1 ubr5 ubr5 skp1 skp1 LOC100701610 LOC100701610 herc3 herc3 keap1 keap1 UBE2O UBE2O ube2j2 ube2j2 LOC100698470 LOC100698470 ube2r2 ube2r2 NHLRC1 NHLRC1 socs1 socs1 Trim32 Trim32 socs3 socs3 LOC100708998 LOC100708998 LOC100697459 LOC100697459 LOC100712348 LOC100712348 LOC100703753 LOC100703753 Cul4b Cul4b LOC100707935 LOC100707935 ube2g2 ube2g2 LOC100708886 LOC100708886 LOC100705406 LOC100705406 Herc1 Herc1 fbxw7 fbxw7 ube4a ube4a ube2g1 ube2g1 Trim37 Trim37 LOC100699888 LOC100699888 ercc8 ercc8 LOC100710656 LOC100710656 LOC100694779 LOC100694779 cul1 cul1 fancl fancl LOC109194151 LOC109194151 anapc13 anapc13 uba1 uba1 ube2f ube2f ube2b ube2b LOC100695807 LOC100695807 anapc11 anapc11 UBA6 UBA6 eloc eloc LOC100695995 LOC100695995 LOC100703032 LOC100703032 LOC100694718 LOC100694718 vhl vhl traf6 traf6 LOC100711003 LOC100711003 ENSONIP00000057827 ENSONIP00000057827 LOC100699741 LOC100699741 LOC100692078 LOC100692078 pias4 pias4 LOC100691078 LOC100691078 UBA3 UBA3 LOC100695653 LOC100695653 det1 det1 ube2i ube2i siah1 siah1 Ube2c Ube2c LOC100692112 LOC100692112 LOC100696261 LOC100696261 ube2ql1 ube2ql1 uba2 uba2 SMURF2 SMURF2 cdc26 cdc26 ddb1 ddb1 LOC100694127 LOC100694127 nedd4l nedd4l sae1 sae1 cdc16 cdc16 LOC100704195 LOC100704195 LOC100705328 LOC100705328 Mdm2 Mdm2 ube2a ube2a LOC100711508 LOC100711508 ube3b ube3b cul4a cul4a syvn1 syvn1 CUL5 CUL5 LOC100707169 LOC100707169 cop1 cop1 rhobtb2 rhobtb2 LOC100695155 LOC100695155
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ube2j1Ubiquitin-conjugating enzyme E2, J1. (317 aa)
LOC100698375UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
ube4bUbiquitination factor E4B, UFD2 homolog (S. cerevisiae). (1381 aa)
anapc4Anaphase promoting complex subunit 4. (808 aa)
LOC100702935Suppressor of cytokine signaling 1b. (234 aa)
ube2zUbiquitin-conjugating enzyme E2Z. (403 aa)
LOC100701023WW domain containing E3 ubiquitin protein ligase 1. (961 aa)
cul2Cullin 2; Belongs to the cullin family. (769 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (896 aa)
LOC100709870Ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
LOC100702014Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1014 aa)
herc2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4816 aa)
trip12Thyroid hormone receptor interactor 12. (2065 aa)
rnf7Ring finger protein 7. (114 aa)
ube3cUbiquitin protein ligase E3C. (1092 aa)
PrknE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (441 aa)
Birc6Baculoviral IAP repeat containing 6. (4824 aa)
rbx1Ring-box 1, E3 ubiquitin protein ligase. (107 aa)
LOC100705137Ubiquitin-conjugating enzyme E2E 2; Belongs to the ubiquitin-conjugating enzyme family. (201 aa)
ube2kUbiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
cdc27Cell division cycle 27. (803 aa)
LOC100697163E3 ubiquitin-protein ligase. (888 aa)
ube2mUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (185 aa)
STUB1STIP1 homology and U-box containing protein 1. (290 aa)
Anapc2Anaphase promoting complex subunit 2; Belongs to the cullin family. (797 aa)
LOC100692645Uncharacterized protein. (863 aa)
I3JU14_ORENIElongin B. (114 aa)
cdc20Cell division cycle 20 homolog. (544 aa)
CUL3Cullin 3; Belongs to the cullin family. (766 aa)
FZR1Fizzy/cell division cycle 20 related 1a. (496 aa)
fbxw8F-box and WD repeat domain containing 8. (658 aa)
anapc5Anaphase promoting complex subunit 5. (771 aa)
skp2S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (419 aa)
LOC100699525Cbl proto-oncogene C, E3 ubiquitin protein ligase. (600 aa)
elobUbiquitin-like domain-containing protein. (122 aa)
ube2hUbiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
anapc10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (186 aa)
huwe1HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1. (4575 aa)
MID1Uncharacterized protein. (689 aa)
uba52Ubiquitin A-52 residue ribosomal protein fusion product 1. (128 aa)
Ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (267 aa)
ube2l3Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (155 aa)
Ube2wUBIQUITIN_CONJUGAT_2 domain-containing protein. (215 aa)
fbxo4F-box protein 4. (396 aa)
pias1Protein inhibitor of activated STAT, 1b. (657 aa)
Ddb2Damage-specific DNA binding protein 2. (443 aa)
I3KEF4_ORENIUncharacterized protein. (590 aa)
LOC100694898Si:rp71-68n21.9. (696 aa)
LOC100704232Uncharacterized protein. (230 aa)
Rchy1Ring finger and CHY zinc finger domain containing 1. (262 aa)
anapc7Anaphase promoting complex subunit 7. (580 aa)
ENSONIP00000020099Ubiquitin-conjugating enzyme E2 G1 isoform X2. (94 aa)
rps27aRibosomal protein S27a. (156 aa)
brca1Uncharacterized protein. (1392 aa)
ubr5Ubiquitin protein ligase E3 component n-recognin 5. (2785 aa)
skp1S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa)
LOC100701610Baculoviral IAP repeat containing 7. (415 aa)
herc3HECT and RLD domain containing E3 ubiquitin protein ligase 3. (1048 aa)
keap1Kelch-like ECH-associated protein 1b. (602 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1389 aa)
ube2j2Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast). (261 aa)
LOC100698470Zgc:175088. (176 aa)
ube2r2Ubiquitin-conjugating enzyme E2R 2; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (412 aa)
socs1Uncharacterized protein. (215 aa)
Trim32Tripartite motif containing 32. (681 aa)
socs3Suppressor of cytokine signaling 3. (205 aa)
LOC100708998UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC100697459Ubiquitin-conjugating enzyme E2 E2. (206 aa)
LOC100712348Ubiquitin-conjugating enzyme E2Nb; Belongs to the ubiquitin-conjugating enzyme family. (254 aa)
LOC100703753CULLIN_2 domain-containing protein; Belongs to the cullin family. (836 aa)
Cul4bCullin-4B. (869 aa)
LOC100707935Rho related BTB domain containing 4. (745 aa)
ube2g2Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (246 aa)
LOC100708886Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
LOC100705406UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (194 aa)
Herc1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4909 aa)
fbxw7F-box and WD repeat domain containing 7. (776 aa)
ube4aUbiquitination factor E4A (UFD2 homolog, yeast). (1077 aa)
ube2g1Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
Trim37Tripartite motif containing 37. (830 aa)
LOC100699888STIP1 homology and U-Box containing protein 1. (284 aa)
ercc8Excision repair cross-complementation group 8. (401 aa)
LOC100710656Kelch-like ECH-associated protein 1a. (613 aa)
LOC100694779UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
cul1Cullin 1b; Belongs to the cullin family. (1038 aa)
fanclFA complementation group L. (365 aa)
LOC109194151CULLIN_2 domain-containing protein; Belongs to the cullin family. (767 aa)
anapc13Anaphase promoting complex subunit 13. (74 aa)
uba1Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1088 aa)
ube2fUbiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family. (340 aa)
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC100695807UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
anapc11APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
UBA6Ubiquitin like modifier activating enzyme 6. (1049 aa)
elocElongin C paralog a; Belongs to the SKP1 family. (112 aa)
LOC100695995Ubiquitin-conjugating enzyme E2Q family member 2. (377 aa)
LOC100703032Protein inhibitor of activated STAT, 2. (509 aa)
LOC100694718E3 ubiquitin-protein ligase. (877 aa)
vhlVon Hippel-Lindau tumor suppressor. (166 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
LOC100711003Cell division cycle 34 homolog (S. cerevisiae) a; Belongs to the ubiquitin-conjugating enzyme family. (242 aa)
ENSONIP00000057827Cell division cycle protein 20 homolog B isoform X1. (315 aa)
LOC100699741UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (138 aa)
LOC100692078Kelch-like family member 13. (679 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
LOC100691078E3 ubiquitin-protein ligase. (844 aa)
UBA3Ubiquitin like modifier activating enzyme 3. (462 aa)
LOC100695653Ubiquitin-conjugating enzyme E2D 4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (164 aa)
det1DET1 partner of COP1 E3 ubiquitin ligase. (575 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
siah1E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
Ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
LOC100692112Protein inhibitor of activated STAT, 1a. (722 aa)
LOC100696261Ubiquitin protein ligase E3A. (874 aa)
ube2ql1Ubiquitin-conjugating enzyme E2Q family-like 1. (291 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (657 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
cdc26Cell division cycle 26 homolog. (97 aa)
ddb1Damage-specific DNA binding protein 1. (1140 aa)
LOC100694127WD_REPEATS_REGION domain-containing protein. (489 aa)
nedd4lNEDD4 like E3 ubiquitin protein ligase. (1289 aa)
sae1SUMO1 activating enzyme subunit 1. (381 aa)
cdc16Cell division cycle 16 homolog (S. cerevisiae). (621 aa)
LOC100704195Uncharacterized protein. (718 aa)
LOC100705328Baculoviral IAP repeat containing 2. (642 aa)
Mdm2MDM2 proto-oncogene; Belongs to the MDM2/MDM4 family. (96 aa)
ube2aUbiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC100711508Midline 1. (689 aa)
ube3bUbiquitin protein ligase E3B. (1068 aa)
cul4aCullin 4A; Belongs to the cullin family. (819 aa)
syvn1Synovial apoptosis inhibitor 1, synoviolin. (642 aa)
CUL5Cullin 5; Belongs to the cullin family. (797 aa)
LOC100707169Ubiquitin-like modifier activating enzyme 3. (455 aa)
cop1COP1 E3 ubiquitin ligase. (717 aa)
rhobtb2Rho related BTB domain containing 2a. (721 aa)
LOC100695155Ubiquitin-conjugating enzyme E2 D2 isoform X1. (181 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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