STRINGSTRING
LOC100694194 LOC100694194 I3IW02_ORENI I3IW02_ORENI PLCB1 PLCB1 LOC100691708 LOC100691708 LOC100689896 LOC100689896 I3IZ02_ORENI I3IZ02_ORENI tyk2 tyk2 bcl2l1 bcl2l1 LOC100694803 LOC100694803 tab3 tab3 LOC102077017 LOC102077017 LOC100693633 LOC100693633 LOC100534578 LOC100534578 LOC100700785 LOC100700785 traf2 traf2 LOC100694769 LOC100694769 I3J6Y0_ORENI I3J6Y0_ORENI LOC100708116 LOC100708116 I3JNN1_ORENI I3JNN1_ORENI ENSONIP00000005160 ENSONIP00000005160 LOC100692065 LOC100692065 trip6 trip6 LOC100705310 LOC100705310 myd88 myd88 ENSONIP00000008001 ENSONIP00000008001 LOC100707250 LOC100707250 rbck1 rbck1 mapk10 mapk10 LOC100709643 LOC100709643 LOC109203135 LOC109203135 LOC100691290 LOC100691290 LOC100708879 LOC100708879 txn2 txn2 LOC100707066 LOC100707066 LOC109194206 LOC109194206 DNM1L DNM1L Trpm2 Trpm2 LOC100693447 LOC100693447 sharpin sharpin LOC100692869 LOC100692869 ripk1 ripk1 LOC100700904 LOC100700904 I3JW29_ORENI I3JW29_ORENI erbin erbin LOC100693282 LOC100693282 LOC100704182 LOC100704182 LOC102078975 LOC102078975 PLCB2 PLCB2 stat1 stat1 mavs mavs LOC100690837 LOC100690837 plcb3 plcb3 LOC100708611 LOC100708611 LOC100700076 LOC100700076 LOC100702139 LOC100702139 LOC100697176 LOC100697176 ENSONIP00000020769 ENSONIP00000020769 Atg16l1 Atg16l1 I3KLB2_ORENI I3KLB2_ORENI ENSONIP00000022595 ENSONIP00000022595 LOC100698148 LOC100698148 sugt1 sugt1 panx1 panx1 LOC100710477 LOC100710477 prkcd prkcd ikbke ikbke nfkbia nfkbia LOC100700876 LOC100700876 LOC100702235 LOC100702235 LOC100702954 LOC100702954 LOC100700270 LOC100700270 I3KYD0_ORENI I3KYD0_ORENI LOC100707786 LOC100707786 brcc3 brcc3 LOC100705884 LOC100705884 ENSONIP00000028492 ENSONIP00000028492 rela rela Mfn2 Mfn2 LOC100704346 LOC100704346 antxr2 antxr2 vdac1 vdac1 ENSONIP00000029967 ENSONIP00000029967 LOC100697001 LOC100697001 ENSONIP00000030978 ENSONIP00000030978 LOC100701183 LOC100701183 ENSONIP00000032073 ENSONIP00000032073 Hsp90ab1 Hsp90ab1 jak1 jak1 casr casr tbk1 tbk1 ENSONIP00000038260 ENSONIP00000038260 LOC102081105 LOC102081105 LOC100697746 LOC100697746 txnip txnip sting1 sting1 LOC100692694 LOC100692694 LOC100700854 LOC100700854 LOC100706560 LOC100706560 I3KJ10_ORENI I3KJ10_ORENI LOC100707445 LOC100707445 I3KF49_ORENI I3KF49_ORENI LOC100705711 LOC100705711 LOC100689869 LOC100689869 ENSONIP00000047097 ENSONIP00000047097 nampt nampt nek7 nek7 nod1 nod1 ENSONIP00000049596 ENSONIP00000049596 atg5 atg5 nod2 nod2 Itpr3 Itpr3 ikbkb ikbkb ENSONIP00000052170 ENSONIP00000052170 LOC100701534 LOC100701534 LOC100710605 LOC100710605 LOC100698785 LOC100698785 traf6 traf6 ripk2 ripk2 LOC100692416 LOC100692416 LOC102078419 LOC102078419 traf3 traf3 mfn1 mfn1 ikbkg ikbkg irf7 irf7 VDAC2 VDAC2 LOC100692379 LOC100692379 LOC100709564 LOC100709564 LOC102083274 LOC102083274 I3JGQ5_ORENI I3JGQ5_ORENI LOC102082520 LOC102082520 irak4 irak4 GABARAPL2 GABARAPL2 LOC100701239 LOC100701239 p2rx7 p2rx7 mcu mcu ENSONIP00000066252 ENSONIP00000066252 LOC100707845 LOC100707845 LOC100702632 LOC100702632 ENSONIP00000067646 ENSONIP00000067646 gabarap gabarap LOC106098416 LOC106098416 ENSONIP00000068794 ENSONIP00000068794 vdac2 vdac2 tab2 tab2 LOC100701982 LOC100701982 tnfaip3 tnfaip3 irf9 irf9 Fadd Fadd ENSONIP00000073042 ENSONIP00000073042 LOC100695783 LOC100695783 card16 card16 LOC100705328 LOC100705328 Atg12 Atg12 LOC100697722 LOC100697722 pkn2 pkn2 I3KGP2_ORENI I3KGP2_ORENI dhx33 dhx33 mapk1 mapk1 LOC109201465 LOC109201465 LOC100704829 LOC100704829 I3KSK9_ORENI I3KSK9_ORENI tab1 tab1 pkn1 pkn1 Nlrx1 Nlrx1 LOC100704139 LOC100704139
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100694194Receptor-interacting serine-threonine kinase 3. (506 aa)
I3IW02_ORENIG protein-coupled receptor, class C, group 6, member A. (865 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1239 aa)
LOC100691708Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (305 aa)
LOC1006898961-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
I3IZ02_ORENIArrestin_C domain-containing protein. (415 aa)
tyk2Tyrosine-protein kinase. (1174 aa)
bcl2l1BCL2 like 1. (232 aa)
LOC100694803Ras homolog family member Cb. (193 aa)
tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (624 aa)
LOC102077017Uncharacterized protein. (220 aa)
LOC100693633PYD and CARD domain containing. (201 aa)
LOC100534578Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC100700785Proline-serine-threonine phosphatase interacting protein 1b. (420 aa)
traf2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (524 aa)
LOC100694769ANTXR cell adhesion molecule 1b. (617 aa)
I3J6Y0_ORENIUncharacterized protein; Belongs to the peptidase C14A family. (383 aa)
LOC100708116Uncharacterized protein; Belongs to the peptidase C14A family. (399 aa)
I3JNN1_ORENIUncharacterized protein; Belongs to the peptidase C14A family. (276 aa)
ENSONIP00000005160NACHT, LRR and PYD domains-containing protein 1a. (747 aa)
LOC100692065Uncharacterized protein. (304 aa)
trip6Uncharacterized protein. (573 aa)
LOC100705310Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (186 aa)
myd88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
ENSONIP00000008001E3 ubiquitin-protein ligase RNF31 isoform X1. (1087 aa)
LOC100707250Uncharacterized protein. (1108 aa)
rbck1RanBP-type and C3HC4-type zinc finger containing 1. (519 aa)
mapk10Mitogen-activated protein kinase. (525 aa)
LOC100709643Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (429 aa)
LOC109203135Uncharacterized protein. (189 aa)
LOC100691290Uncharacterized protein. (189 aa)
LOC100708879Protein kinase N1b. (956 aa)
txn2Thioredoxin 2. (172 aa)
LOC100707066Interleukin-1. (244 aa)
LOC109194206Caspase 10, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (470 aa)
DNM1LDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
Trpm2Transient receptor potential cation channel, subfamily M, member 2. (1441 aa)
LOC100693447Mitogen-activated protein kinase. (364 aa)
sharpinRanBP2-type domain-containing protein. (436 aa)
LOC100692869Component of inhibitor of nuclear factor kappa B kinase complex. (757 aa)
ripk1Receptor (TNFRSF)-interacting serine-threonine kinase 1, like. (678 aa)
LOC100700904Mitogen-activated protein kinase. (365 aa)
I3JW29_ORENITNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa)
erbinErbb2 interacting protein. (1413 aa)
LOC100693282Interleukin-1. (255 aa)
LOC100704182ANTXR cell adhesion molecule 1a. (609 aa)
LOC102078975Caspase recruitment domain family, member 9. (531 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1267 aa)
stat1Signal transducer and activator of transcription. (781 aa)
mavsCARD_2 domain-containing protein. (552 aa)
LOC100690837Thioredoxin; Belongs to the thioredoxin family. (107 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1261 aa)
LOC100708611Sharpin and rbck1 related. (708 aa)
LOC100700076Proline-serine-threonine phosphatase interacting protein 1a. (409 aa)
LOC100702139Uncharacterized protein; Belongs to the peptidase C14A family. (485 aa)
LOC100697176TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (587 aa)
ENSONIP00000020769NACHT, LRR and PYD domains-containing protein 1b allele 3-like isoform X1. (427 aa)
Atg16l1ATG16 autophagy related 16-like 1 (S. cerevisiae). (612 aa)
I3KLB2_ORENIUncharacterized protein. (200 aa)
ENSONIP00000022595NACHT, LRR and PYD domains-containing protein 3. (935 aa)
LOC100698148Protein kinase domain-containing protein. (777 aa)
sugt1SGT1 homolog, MIS12 kinetochore complex assembly cochaperone. (323 aa)
panx1Pannexin; Structural component of the gap junctions and the hemichannels; Belongs to the pannexin family. (384 aa)
LOC100710477Ras homolog gene family, member Ab. (193 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
ikbkeInhibitor of nuclear factor kappa B kinase subunit epsilon. (721 aa)
nfkbiaNuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (318 aa)
LOC100700876Anthrax toxin receptor; Belongs to the ATR family. (565 aa)
LOC100702235Mitogen-activated protein kinase. (487 aa)
LOC100702954Interferon regulatory factor 3. (466 aa)
LOC100700270BH4_2 domain-containing protein. (197 aa)
I3KYD0_ORENIJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
LOC100707786JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
brcc3BRCA1/BRCA2-containing complex, subunit 3. (260 aa)
LOC100705884BZIP domain-containing protein; Belongs to the bZIP family. (307 aa)
ENSONIP00000028492NACHT, LRR and PYD domains-containing protein 1b allele 2-like. (314 aa)
relaV-rel avian reticuloendotheliosis viral oncogene homolog A. (616 aa)
Mfn2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (796 aa)
LOC100704346TRAF family member-associated NF-kappa-B activator isoform X2. (355 aa)
antxr2Anthrax toxin receptor; Belongs to the ATR family. (504 aa)
vdac1Voltage-dependent anion channel 1. (318 aa)
ENSONIP00000029967NACHT, LRR and PYD domains-containing protein 1. (758 aa)
LOC100697001Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
ENSONIP00000030978Caspase recruitment domain-containing protein 8. (414 aa)
LOC100701183Mitogen-activated protein kinase. (367 aa)
ENSONIP00000032073Interferon a3-like. (210 aa)
Hsp90ab1Heat shock protein 90, alpha (cytosolic), class B member 1. (752 aa)
jak1Tyrosine-protein kinase. (1183 aa)
casrCalcium-sensing receptor. (940 aa)
tbk1TANK-binding kinase 1. (746 aa)
ENSONIP00000038260Permeability factor 2. (86 aa)
LOC102081105TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (169 aa)
LOC100697746TNF_2 domain-containing protein. (239 aa)
txnipThioredoxin-interacting protein. (396 aa)
sting1Stimulator of interferon genes protein. (403 aa)
LOC100692694Inositol 1,4,5-trisphosphate receptor, type 1b. (2781 aa)
LOC100700854NACHT, LRR and PYD domains-containing protein 3-like. (1279 aa)
LOC100706560Mitogen-activated protein kinase. (363 aa)
I3KJ10_ORENIDynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
LOC100707445Uncharacterized protein. (193 aa)
I3KF49_ORENICaspase 20, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (467 aa)
LOC100705711Cytochrome b-245, beta polypeptide (chronic granulomatous disease). (565 aa)
LOC100689869Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 2; Belongs to the 14-3-3 family. (271 aa)
ENSONIP00000047097Uncharacterized protein LOC109196975. (181 aa)
namptNicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family. (509 aa)
nek7NIMA-related kinase 7. (332 aa)
nod1Nucleotide-binding oligomerization domain containing 1. (953 aa)
ENSONIP00000049596NACHT, LRR and PYD domains-containing protein 1b allele 2 isoform X1. (91 aa)
atg5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
nod2Nucleotide-binding oligomerization domain containing 2. (1004 aa)
Itpr3Inositol 1,4,5-trisphosphate receptor, type 3. (2638 aa)
ikbkbInhibitor of nuclear factor kappa B kinase subunit beta. (757 aa)
ENSONIP00000052170Cathepsin B. (356 aa)
LOC100701534Signal transducer and activator of transcription. (802 aa)
LOC100710605Zgc:56235. (313 aa)
LOC100698785Uncharacterized protein. (193 aa)
traf6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
ripk2Receptor-interacting serine-threonine kinase 2. (570 aa)
LOC100692416Mitogen-activated protein kinase. (376 aa)
LOC102078419NACHT domain-containing protein. (1689 aa)
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (594 aa)
mfn1Mitofusin 1b; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (784 aa)
ikbkgInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (621 aa)
irf7Interferon regulatory factor 7. (461 aa)
VDAC2Voltage dependent anion channel 2. (303 aa)
LOC100692379Mitogen-activated protein kinase. (448 aa)
LOC100709564Signal transducer and activator of transcription 1-alpha/beta. (756 aa)
LOC102083274Interferon alpha. (206 aa)
I3JGQ5_ORENIUncharacterized protein. (1603 aa)
LOC102082520Uncharacterized protein. (435 aa)
irak4Interleukin-1 receptor-associated kinase 4. (463 aa)
GABARAPL2GABA type A receptor associated protein like 2. (126 aa)
LOC100701239TRIF-NTD domain-containing protein. (550 aa)
p2rx7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (594 aa)
mcuMitochondrial calcium uniporter. (376 aa)
ENSONIP00000066252G-protein coupled receptor family C group 6 member A-like. (593 aa)
LOC100707845Cathepsin Ba; Belongs to the peptidase C1 family. (334 aa)
LOC100702632Mitogen-activated protein kinase. (366 aa)
ENSONIP00000067646Permeability factor 2 isoform X2. (103 aa)
gabarapGamma-aminobutyric acid receptor-associated protein. (152 aa)
LOC106098416Interleukin-8-like. (123 aa)
ENSONIP00000068794Cathepsin B. (354 aa)
vdac2Voltage-dependent anion channel 2. (317 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (738 aa)
LOC100701982Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (770 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (861 aa)
irf9Interferon regulatory factor 9. (461 aa)
FaddUncharacterized protein. (209 aa)
ENSONIP00000073042Interferon a3-like. (149 aa)
LOC100695783Uncharacterized protein. (1136 aa)
card16Uncharacterized protein. (96 aa)
LOC100705328Baculoviral IAP repeat containing 2. (642 aa)
Atg12Ubiquitin-like protein ATG12. (225 aa)
LOC100697722Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (398 aa)
pkn2Protein kinase N2. (1030 aa)
I3KGP2_ORENIAIG1-type G domain-containing protein. (1494 aa)
dhx33DEAH (Asp-Glu-Ala-His) box polypeptide 33. (681 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC109201465NACHT, LRR and PYD domains-containing protein 12-like isoform X1. (1579 aa)
LOC10070482914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (270 aa)
I3KSK9_ORENIInositol 1,4,5-trisphosphate receptor, type 1a. (2718 aa)
tab1TGF-beta activated kinase 1/MAP3K7 binding protein 1. (510 aa)
pkn1Protein kinase N1a. (953 aa)
Nlrx1NLR family member X1. (985 aa)
LOC100704139Mitogen-activated protein kinase. (481 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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